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| | HIC1 | Uncharacterized protein. (620 aa) |
| | PML | Uncharacterized protein. (873 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (426 aa) |
| | EPHA2 | EPH receptor A2. (976 aa) |
| | BOK | BCL2 family apoptosis regulator BOK. (211 aa) |
| | G1R9J5_NOMLE | SAM domain-containing protein. (574 aa) |
| | RHOT2 | Miro domain-containing protein. (187 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1273 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | HIP1 | Huntingtin interacting protein 1. (1023 aa) |
| | PDK2 | Protein-serine/threonine kinase. (415 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | UBE4B | Ubiquitination factor E4B. (1209 aa) |
| | LOC100592336 | PH_3 domain-containing protein. (247 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (385 aa) |
| | BCL2L1 | BCL2 like 1. (217 aa) |
| | IFI6 | Interferon alpha inducible protein 6. (138 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (424 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (350 aa) |
| | DIDO1 | Death inducer-obliterator 1. (2204 aa) |
| | E2F1 | E2F transcription factor 1. (391 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | CTTN | SH3 domain-containing protein. (549 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha. (439 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (583 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | RNF41 | Ring finger protein 41. (317 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | DAP | Uncharacterized protein. (102 aa) |
| | ZNF622 | Zinc finger protein 622. (477 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (914 aa) |
| | SIRT1 | Sirtuin 1. (734 aa) |
| | DAP3 | Death associated protein 3. (386 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa) |
| | ABL1 | Tyrosine-protein kinase. (1006 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (135 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (988 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | IFI16 | Interferon gamma inducible protein 16. (723 aa) |
| | BRSK2 | BR serine/threonine kinase 2. (739 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit. (3853 aa) |
| | CASP8AP2 | Caspase 8 associated protein 2. (1971 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1343 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (744 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (381 aa) |
| | ENSNLEP00000047501 | IF rod domain-containing protein; Belongs to the intermediate filament family. (376 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1347 aa) |
| | DEDD | Death effector domain containing. (347 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) |
| | PDX1 | Pancreatic and duodenal homeobox 1. (283 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (386 aa) |
| | PCGF2 | RING-type domain-containing protein. (274 aa) |
| | GSKIP | GSK3B interacting protein. (144 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (676 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (759 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1594 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3419 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (423 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (100 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (247 aa) |
| | CD5 | Uncharacterized protein. (592 aa) |
| | MKNK2 | Uncharacterized protein. (272 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | CHEK2 | Checkpoint kinase 2. (487 aa) |
| | SORT1 | Sortilin. (694 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (397 aa) |
| | DAPK3 | Death associated protein kinase 3. (407 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | CHAC1 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (264 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa) |
| | CD27 | CD27 molecule. (259 aa) |
| | MELK | Non-specific serine/threonine protein kinase. (651 aa) |
| | FASTK | Fas activated serine/threonine kinase. (549 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (203 aa) |
| | LGALS12 | Galectin. (337 aa) |
| | PDE3A | Phosphodiesterase. (1141 aa) |
| | BAX | Uncharacterized protein. (194 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | MLH1 | MutL homolog 1. (756 aa) |
| | PAWR | Pro-apoptotic WT1 regulator. (340 aa) |
| | DAPK1 | Death associated protein kinase 1. (1430 aa) |
| | ITPRIPL2 | ITPRIP like 2. (535 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | ELL3 | Elongation factor for RNA polymerase II 3. (397 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | PDK1 | Protein-serine/threonine kinase. (456 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1823 aa) |
| | ENSNLEP00000047002 | Uncharacterized protein. (108 aa) |
| | RHOT1 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (691 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | BAG6 | BCL2 associated athanogene 6. (1119 aa) |
| | ZNF385B | Zinc finger protein 385B. (471 aa) |
| | NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (144 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa) |
| | FNIP2 | Folliculin interacting protein 2. (1113 aa) |
| | BCL2L10 | BCL2 like 10. (231 aa) |
| | SST | Somatostatin. (116 aa) |
| | QRICH1 | Glutamine rich 1. (777 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (512 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (523 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) |
| | CASP5 | Caspase 5; Belongs to the peptidase C14A family. (448 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3055 aa) |
| | USP28 | Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1068 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | SPI1 | Spi-1 proto-oncogene. (271 aa) |
| | SSTR3 | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (418 aa) |
| | TM2D1 | TM2 domain containing 1. (207 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (977 aa) |
| | ATF4 | BZIP domain-containing protein. (351 aa) |
| | FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) |
| | CIDEB | Cell death inducing DFFA like effector b. (220 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (506 aa) |
| | ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1492 aa) |
| | G1S167_NOMLE | Uncharacterized protein. (410 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (471 aa) |
| | CD70 | Tumor necrosis factor ligand 8A; Belongs to the tumor necrosis factor family. (193 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | BNIP3L | BCL2 interacting protein 3 like. (219 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1071 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (992 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | SIVA1 | Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (232 aa) |
| | CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (448 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (293 aa) |
| | BAG3 | BCL2 associated athanogene 3. (574 aa) |
| | MOAP1 | Modulator of apoptosis 1. (351 aa) |
| | IFI27L2 | Interferon alpha inducible protein 27 like 2. (130 aa) |
| | WWOX | WW domain containing oxidoreductase. (413 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa) |
| | FLCN | Folliculin. (542 aa) |
| | TMEM109 | Transmembrane protein 109. (243 aa) |
| | UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1403 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | STK25 | Serine/threonine kinase 25. (416 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | MYBBP1A | MYB binding protein 1a. (1271 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (447 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa) |
| | KRT18 | Keratin 18; Belongs to the intermediate filament family. (430 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa) |
| | FAIM2 | Uncharacterized protein; Belongs to the BI1 family. (254 aa) |
| | COL2A1 | Collagen type II alpha 1 chain. (1487 aa) |
| | VDR | Vitamin D receptor. (427 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1304 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa) |
| | G1SB75_NOMLE | Uncharacterized protein. (81 aa) |
| | RTL10 | Retrotransposon Gag like 10. (350 aa) |
| | DEDD2 | Death effector domain containing 2. (326 aa) |
| | ITPRIP | Inositol 1,4,5-trisphosphate receptor interacting protein. (458 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa) |
| | ENSNLEP00000024590 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (479 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | DAPL1 | Uncharacterized protein. (134 aa) |
| | ENSNLEP00000048966 | IF rod domain-containing protein; Belongs to the intermediate filament family. (171 aa) |
| | TFPT | TCF3 fusion partner. (253 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (604 aa) |
| | G0S2 | G0/G1 switch 2. (103 aa) |
| | TOPORS | TOP1 binding arginine/serine rich protein. (1053 aa) |
| | FGFR3 | Receptor protein-tyrosine kinase. (583 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1136 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | ENSNLEP00000026081 | Protein kinase domain-containing protein. (407 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | STK3 | Serine/threonine kinase 3. (519 aa) |
| | TNFRSF25 | TNF receptor superfamily member 25. (426 aa) |
| | UMOD | Uromodulin. (676 aa) |
| | CD38 | CD38 molecule. (300 aa) |
| | HINT1 | HIT domain-containing protein. (126 aa) |
| | COA8 | Cytochrome c oxidase assembly factor 8. (206 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (704 aa) |
| | AEN | Apoptosis enhancing nuclease. (325 aa) |
| | DELE1 | DAP3 binding cell death enhancer 1. (536 aa) |
| | STK4 | Serine/threonine kinase 4. (490 aa) |
| | PERP | P53 apoptosis effector related to PMP22. (186 aa) |
| | ENSNLEP00000028972 | Uncharacterized protein. (122 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | SNW1 | SNW domain containing 1. (571 aa) |
| | ENSNLEP00000029160 | IF rod domain-containing protein; Belongs to the intermediate filament family. (143 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | DPF2 | Double PHD fingers 2. (405 aa) |
| | LOC100605818 | BZIP domain-containing protein. (347 aa) |
| | TNFRSF10D | Uncharacterized protein. (226 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (987 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1142 aa) |
| | EDA2R | Ectodysplasin A2 receptor. (318 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (382 aa) |
| | BNIP3 | Uncharacterized protein. (231 aa) |
| | ENSNLEP00000031524 | Uncharacterized protein. (55 aa) |
| | YAP1 | Uncharacterized protein. (418 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (716 aa) |
| | LOC101178681 | Uncharacterized protein. (661 aa) |
| | ARL6IP5 | PRA1 family protein. (188 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | ENSNLEP00000032543 | Uncharacterized protein. (168 aa) |
| | FHIT | Bis(5'-adenosyl)-triphosphatase. (150 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | SELENOK | Selenoprotein K. (93 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | CTNNA1 | Catenin alpha 1. (895 aa) |
| | ENSNLEP00000033584 | IF rod domain-containing protein; Belongs to the intermediate filament family. (413 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | PPP1R15A | Protein phosphatase 1 regulatory subunit 15A. (677 aa) |
| | GGCT | Uncharacterized protein. (188 aa) |
| | TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa) |
| | ENSNLEP00000035164 | Uncharacterized protein. (198 aa) |
| | ENSNLEP00000035372 | TGF_BETA_2 domain-containing protein. (392 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (182 aa) |
| | IL6R | Interleukin 6 receptor. (420 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1008 aa) |
| | EP300 | E1A binding protein p300. (2306 aa) |
| | STK24 | Serine/threonine kinase 24. (443 aa) |
| | IVNS1ABP | Influenza virus NS1A binding protein. (642 aa) |
| | ENSNLEP00000036398 | Uncharacterized protein. (163 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (699 aa) |
| | ZDHHC3 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (333 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | ENSNLEP00000036789 | SKIP_SNW domain-containing protein. (443 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (214 aa) |
| | ANXA6 | Annexin. (673 aa) |
| | BAD | Uncharacterized protein. (82 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1031 aa) |
| | DDX47 | DEAD-box helicase 47; Belongs to the DEAD box helicase family. (455 aa) |
| | PRODH | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (595 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (297 aa) |
| | HTRA2 | HtrA serine peptidase 2. (458 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) |
| | CRADD | CASP2 and RIPK1 domain containing adaptor with death domain. (199 aa) |
| | ENSNLEP00000040381 | Uncharacterized protein. (760 aa) |
| | BCL3 | BCL3 transcription coactivator. (453 aa) |
| | NF1 | Neurofibromin 1. (2839 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | LOC100593010 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (844 aa) |
| | BBC3 | BCL2 binding component 3. (237 aa) |
| | IL7 | Interleukin 7. (179 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PHLDA3 | Pleckstrin homology like domain family A member 3. (127 aa) |
| | TMEM117 | Transmembrane protein 117. (514 aa) |
| | CD3E | CD3e molecule. (198 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1884 aa) |
| | BEX3 | Brain expressed X-linked 3. (121 aa) |
| | PIDD1 | P53-induced death domain protein 1. (883 aa) |
| | ENSNLEP00000043034 | Uncharacterized protein. (52 aa) |
| | SCN2A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1939 aa) |
| | SHISA5 | Shisa family member 5. (245 aa) |
| | PPM1F | Protein phosphatase, Mg2+/Mn2+ dependent 1F. (454 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa) |
| | ENSNLEP00000044067 | Uncharacterized protein. (108 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | ENSNLEP00000044511 | POU domain protein. (242 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | SKIL | SKI like proto-oncogene. (683 aa) |
| | DAB2IP | DAB2 interacting protein. (1159 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (387 aa) |
| | MFF | Mitochondrial fission factor. (342 aa) |
| | BCL2A1 | Uncharacterized protein. (205 aa) |
| | IFI27L1 | Uncharacterized protein. (93 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | ENSNLEP00000046012 | IF rod domain-containing protein; Belongs to the intermediate filament family. (198 aa) |
| | NANOS3 | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (193 aa) |
| | MLLT11 | MLLT11 transcription factor 7 cofactor. (90 aa) |
| | ENSNLEP00000046451 | IF rod domain-containing protein; Belongs to the intermediate filament family. (417 aa) |
