STRINGSTRING
CXCL13 CXCL13 S100A8 S100A8 IL6 IL6 ENSNLEP00000046458 ENSNLEP00000046458 BCR BCR ITGA9 ITGA9 ENSNLEP00000046123 ENSNLEP00000046123 CXCL8 CXCL8 PIP5K1C PIP5K1C IL1B IL1B CCR7 CCR7 ENSNLEP00000044243 ENSNLEP00000044243 LOC100591994 LOC100591994 LOC100602058 LOC100602058 PF4 PF4 EMP2 EMP2 LOC100607085 LOC100607085 EDN3 EDN3 ENSNLEP00000041273 ENSNLEP00000041273 ENSNLEP00000040637 ENSNLEP00000040637 NF1 NF1 IL17RC IL17RC CCL22 CCL22 B4GALT1 B4GALT1 ENSNLEP00000038427 ENSNLEP00000038427 LOC100595480 LOC100595480 EPX EPX IL6R IL6R CCL20 CCL20 RABGEF1 RABGEF1 NUP85 NUP85 NCKAP1L NCKAP1L SELENOK SELENOK ENSNLEP00000032876 ENSNLEP00000032876 PRTN3 PRTN3 PIK3R1 PIK3R1 JAM3 JAM3 CTSG CTSG CCL25 CCL25 PDE4B PDE4B CD177 CD177 UMOD UMOD VAV1 VAV1 FCER1G FCER1G LOC100607679 LOC100607679 TNFSF11 TNFSF11 ENSNLEP00000024537 ENSNLEP00000024537 PREX1 PREX1 SRP54 SRP54 PIKFYVE PIKFYVE HRH1 HRH1 C5AR1 C5AR1 IRAK4 IRAK4 CHGA CHGA NINJ1 NINJ1 EDNRB EDNRB WDR1 WDR1 DPEP1 DPEP1 PLA2G1B PLA2G1B PDGFB PDGFB GBF1 GBF1 PECAM1 PECAM1 UMODL1 UMODL1 CCL4 CCL4 LOC100602388 LOC100602388 CCL18 CCL18 CCL23 CCL23 CCL15 CCL15 CCL14 CCL14 CCL16 CCL16 CCL5 CCL5 TGFB2 TGFB2 LGALS3 LGALS3 GP2 GP2 PPIB PPIB EDN2 EDN2 CSF3R CSF3R STAT5B STAT5B ITGA1 ITGA1 CXCL17 CXCL17 SFTPD SFTPD TRIM55 TRIM55 S100A12 S100A12 S100A9 S100A9 MCOLN2 MCOLN2 SCG2 SCG2 PIK3CD PIK3CD SIRPA SIRPA PIK3CG PIK3CG TNFRSF11A TNFRSF11A CCL26 CCL26 CCL24 CCL24 KIT KIT CXCL10 CXCL10 CXCL9 CXCL9 CXCL11 CXCL11 CXCL2 CXCL2 CXCL3 CXCL3 CXCL5 CXCL5 PPBP PPBP PF4V1 PF4V1 CXCL6 CXCL6 IL17RA IL17RA SLC37A4 SLC37A4 JAML JAML LOC100580192 LOC100580192 LBP LBP LOC100580385 LOC100580385 KITLG KITLG TREM1 TREM1 CCL21 CCL21 JAGN1 JAGN1 MSMP MSMP PTPRO PTPRO PPIA PPIA IL17A IL17A CSF1 CSF1 G1QRB3_NOMLE G1QRB3_NOMLE CCL17 CCL17 CX3CL1 CX3CL1 ITGB2 ITGB2 CXADR CXADR TAFA4 TAFA4 CCL1 CCL1 CCL13 CCL13 CCL8 CCL8 CCL11 CCL11 G1QLB3_NOMLE G1QLB3_NOMLE VAV3 VAV3 ANXA1 ANXA1 CALCA CALCA G1QJP9_NOMLE G1QJP9_NOMLE BSG BSG FLT1 FLT1 ROR2 ROR2 SYK SYK ARHGEF5 ARHGEF5 ENSNLEP00000047342 ENSNLEP00000047342
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CXCL13C-X-C motif chemokine ligand 13. (109 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
IL6Uncharacterized protein. (258 aa)
ENSNLEP00000046458Uncharacterized protein. (125 aa)
BCRBCR activator of RhoGEF and GTPase. (1271 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
ENSNLEP00000046123Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
PIP5K1CPIPK domain-containing protein. (759 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
ENSNLEP00000044243IGv domain-containing protein. (199 aa)
LOC100591994C-C motif chemokine. (203 aa)
LOC100602058C-C motif chemokine. (92 aa)
PF4C-X-C motif chemokine. (106 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
LOC100607085SCY domain-containing protein. (114 aa)
EDN3Uncharacterized protein. (211 aa)
ENSNLEP00000041273Uncharacterized protein. (190 aa)
ENSNLEP00000040637Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
NF1Neurofibromin 1. (2839 aa)
IL17RCIL17_R_N domain-containing protein. (549 aa)
CCL22C-C motif chemokine. (93 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (361 aa)
ENSNLEP00000038427Uncharacterized protein. (305 aa)
LOC100595480SCY domain-containing protein. (103 aa)
EPXEosinophil peroxidase. (639 aa)
IL6RInterleukin 6 receptor. (420 aa)
CCL20C-C motif chemokine. (96 aa)
RABGEF1RAB guanine nucleotide exchange factor 1. (497 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (659 aa)
NCKAP1LNCK associated protein 1 like. (1109 aa)
SELENOKSelenoprotein K. (93 aa)
ENSNLEP00000032876Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa)
PRTN3Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (160 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
JAM3Junctional adhesion molecule 3. (275 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
CCL25SCY domain-containing protein. (131 aa)
PDE4BPhosphodiesterase. (736 aa)
CD177Uncharacterized protein. (140 aa)
UMODUromodulin. (676 aa)
VAV1Uncharacterized protein. (739 aa)
FCER1GUncharacterized protein. (112 aa)
LOC100607679SCY domain-containing protein. (98 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
ENSNLEP00000024537A20-type domain-containing protein. (112 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1537 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (515 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
CHGAChromogranin A. (460 aa)
NINJ1Ninjurin 1. (152 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
WDR1WD repeat domain 1. (560 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (367 aa)
PLA2G1BPhospholipase A(2). (148 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (721 aa)
UMODL1Uromodulin like 1. (1446 aa)
CCL4C-C motif chemokine. (92 aa)
LOC100602388C-C motif chemokine. (92 aa)
CCL18C-C motif chemokine. (89 aa)
CCL23C-C motif chemokine. (137 aa)
CCL15C-C motif chemokine. (113 aa)
CCL14C-C motif chemokine. (109 aa)
CCL16SCY domain-containing protein. (75 aa)
CCL5C-C motif chemokine. (91 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LGALS3Galectin. (250 aa)
GP2Glycoprotein 2. (535 aa)
PPIBPeptidylprolyl isomerase B. (184 aa)
EDN2Endothelin 2. (177 aa)
CSF3RColony stimulating factor 3 receptor. (857 aa)
STAT5BSignal transducer and activator of transcription. (650 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
SFTPDSurfactant protein D. (375 aa)
TRIM55Tripartite motif containing 55. (547 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (91 aa)
S100A9Protein S100; Belongs to the S-100 family. (112 aa)
MCOLN2Mucolipin 2. (566 aa)
SCG2Secretogranin II. (542 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1077 aa)
SIRPAUncharacterized protein. (486 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
TNFRSF11ATNF receptor superfamily member 11a. (595 aa)
CCL26C-C motif chemokine. (94 aa)
CCL24C-C motif chemokine ligand 24. (118 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
CXCL10C-X-C motif chemokine. (98 aa)
CXCL9C-X-C motif chemokine. (125 aa)
CXCL11C-X-C motif chemokine. (94 aa)
CXCL2C-X-C motif chemokine. (106 aa)
CXCL3C-X-C motif chemokine. (107 aa)
CXCL5C-X-C motif chemokine. (114 aa)
PPBPC-X-C motif chemokine. (128 aa)
PF4V1C-X-C motif chemokine. (101 aa)
CXCL6C-X-C motif chemokine. (114 aa)
IL17RAInterleukin 17 receptor A. (817 aa)
SLC37A4Solute carrier family 37 member 4. (399 aa)
JAMLJunction adhesion molecule like. (394 aa)
LOC100580192G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (351 aa)
LBPLipopolysaccharide binding protein. (481 aa)
LOC100580385SCY domain-containing protein. (114 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
TREM1Triggering receptor expressed on myeloid cells 1. (234 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
JAGN1Jagunal homolog 1. (183 aa)
MSMPBeta-microseminoprotein. (139 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1183 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
IL17AInterleukin 17A. (155 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
G1QRB3_NOMLEC-C motif chemokine. (79 aa)
CCL17C-C motif chemokine. (94 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
ITGB2Integrin beta. (762 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
TAFA4TAFA chemokine like family member 4. (140 aa)
CCL1C-C motif chemokine. (96 aa)
CCL13C-C motif chemokine. (98 aa)
CCL8C-C motif chemokine. (99 aa)
CCL11C-C motif chemokine. (97 aa)
G1QLB3_NOMLEC-C motif chemokine. (138 aa)
VAV3Vav guanine nucleotide exchange factor 3. (799 aa)
ANXA1Annexin. (346 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
G1QJP9_NOMLEPeptidase S1 domain-containing protein. (178 aa)
BSGUncharacterized protein. (345 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (915 aa)
SYKTyrosine-protein kinase. (532 aa)
ARHGEF5DH domain-containing protein. (302 aa)
ENSNLEP00000047342C-X-C motif chemokine. (94 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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