28 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	RB1	RB transcriptional corepressor 1. (919 aa)
	EZR	Ezrin. (586 aa)
	ENSNLEP00000043017	HATPase_c domain-containing protein. (648 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	FKBP8	FKBP prolyl isomerase 8. (397 aa)
	ENSNLEP00000037566	TPR_REGION domain-containing protein. (217 aa)
	ENSNLEP00000037385	Uncharacterized protein. (437 aa)
	ENSNLEP00000035652	Uncharacterized protein; Belongs to the calmodulin family. (123 aa)
	GJA5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (150 aa)
	PPIL1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (665 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (853 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	HSPA2	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (601 aa)
	KCNA1	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
	RRM1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
	NUMA1	Uncharacterized protein. (947 aa)
	SMTNL1	Smoothelin like 1. (493 aa)
	KEAP1	BTB domain-containing protein. (395 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (923 aa)
	DFFB	CIDE-N domain-containing protein. (296 aa)
	FN1	Fibronectin 1. (2477 aa)
	NCOA3	Nuclear receptor coactivator. (1419 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2A2	AP2M1	ENSNLEP00000010742	ENSNLEP00000007470	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.994
AP2A2	CLTC	ENSNLEP00000010742	ENSNLEP00000001008	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.973
AP2M1	AP2A2	ENSNLEP00000007470	ENSNLEP00000010742	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.994
AP2M1	CLTC	ENSNLEP00000007470	ENSNLEP00000001008	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.889
CALM1	FKBP8	ENSNLEP00000029615	ENSNLEP00000038356	Calmodulin 1; Belongs to the calmodulin family.	FKBP prolyl isomerase 8.	0.734
CALM1	HSP90AA1	ENSNLEP00000029615	ENSNLEP00000025829	Calmodulin 1; Belongs to the calmodulin family.	Heat shock protein 90 alpha family class A member 1.	0.900
CLTC	AP2A2	ENSNLEP00000001008	ENSNLEP00000010742	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.973
CLTC	AP2M1	ENSNLEP00000001008	ENSNLEP00000007470	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.889
CLTC	EZR	ENSNLEP00000001008	ENSNLEP00000045659	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Ezrin.	0.411
CLTC	HSPA2	ENSNLEP00000001008	ENSNLEP00000022984	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.	0.466
CTNNB1	ENSNLEP00000043017	ENSNLEP00000006991	ENSNLEP00000043017	Catenin beta 1.	HATPase_c domain-containing protein.	0.437
CTNNB1	EZR	ENSNLEP00000006991	ENSNLEP00000045659	Catenin beta 1.	Ezrin.	0.599
CTNNB1	FYN	ENSNLEP00000006991	ENSNLEP00000041056	Catenin beta 1.	Tyrosine-protein kinase.	0.972
CTNNB1	GAPDH	ENSNLEP00000006991	ENSNLEP00000005031	Catenin beta 1.	Glyceraldehyde-3-phosphate dehydrogenase.	0.543
CTNNB1	HSP90AA1	ENSNLEP00000006991	ENSNLEP00000025829	Catenin beta 1.	Heat shock protein 90 alpha family class A member 1.	0.487
CTNNB1	HSP90AB1	ENSNLEP00000006991	ENSNLEP00000027651	Catenin beta 1.	Heat shock protein 90 alpha family class B member 1.	0.437
CTNNB1	RRM1	ENSNLEP00000006991	ENSNLEP00000021038	Catenin beta 1.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.485
CTNNB1	SMAD2	ENSNLEP00000006991	ENSNLEP00000023604	Catenin beta 1.	Mothers against decapentaplegic homolog.	0.938
ENSNLEP00000037385	ENSNLEP00000037566	ENSNLEP00000037385	ENSNLEP00000037566	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.563
ENSNLEP00000037385	FKBP8	ENSNLEP00000037385	ENSNLEP00000038356	Uncharacterized protein.	FKBP prolyl isomerase 8.	0.563

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