STRINGSTRING
FGF11 FGF11 DRD4 DRD4 FGF14 FGF14 CHRNA7 CHRNA7 PDZD3 PDZD3 SCN4B SCN4B FXYD6 FXYD6 GRM2 GRM2 KCNS1 KCNS1 NEDD4 NEDD4 CABP2 CABP2 CABP4 CABP4 CACNG6 CACNG6 CACNG8 CACNG8 CACNG7 CACNG7 KCNMB2 KCNMB2 G1QZ78_NOMLE G1QZ78_NOMLE NRXN2 NRXN2 ABCC9 ABCC9 YWHAH YWHAH RRAD RRAD CRISP3 CRISP3 CRISP1 CRISP1 CAV3 CAV3 ITPR1 ITPR1 AMIGO1 AMIGO1 STX8 STX8 SLC30A1 SLC30A1 KCNS3 KCNS3 VTI1B VTI1B FKBP1B FKBP1B NOS1 NOS1 CACNG1 CACNG1 PRKCZ PRKCZ KCNIP3 KCNIP3 SNTA1 SNTA1 LRRC38 LRRC38 REM1 REM1 ENSNLEP00000048122 ENSNLEP00000048122 WNK2 WNK2 CABP5 CABP5 SUMO1 SUMO1 RACK1 RACK1 KCNAB3 KCNAB3 GPLD1 GPLD1 WNK1 WNK1 ENSNLEP00000045038 ENSNLEP00000045038 LOC100583245 LOC100583245 COMMD1 COMMD1 PRKCB PRKCB KCNIP2 KCNIP2 SCN2B SCN2B YWHAE YWHAE FGF13 FGF13 LOC100590514 LOC100590514 PTPN3 PTPN3 VAMP8 VAMP8 CRISP2 CRISP2 STIM2 STIM2 CAMK2D CAMK2D FXYD2 FXYD2 SCN3B SCN3B NRXN1 NRXN1 ARPP19 ARPP19 KCNE2 KCNE2 KCNAB1 KCNAB1 KCNIP1 KCNIP1 CACNG4 CACNG4 ENSNLEP00000035652 ENSNLEP00000035652 DPP6 DPP6 KCNE3 KCNE3 STX1A STX1A LOC101179053 LOC101179053 KCNMB3 KCNMB3 VAMP5 VAMP5 CAV1 CAV1 RANGRF RANGRF ENSNLEP00000031915 ENSNLEP00000031915 MUSTN1 MUSTN1 ENSA ENSA KCNAB2 KCNAB2 AMIGO2 AMIGO2 ENSNLEP00000031077 ENSNLEP00000031077 FGF12 FGF12 LOC100582441 LOC100582441 ENSNLEP00000029822 ENSNLEP00000029822 CALM1 CALM1 STOML1 STOML1 STIM1 STIM1 DLG1 DLG1 CABP1 CABP1 PRSS41 PRSS41 AKT1 AKT1 KCNE4 KCNE4 HPCAL4 HPCAL4 FXYD4 FXYD4 ENSNLEP00000026357 ENSNLEP00000026357 SGK2 SGK2 ENSNLEP00000025820 ENSNLEP00000025820 DPP10 DPP10 STIMATE STIMATE KCNMB4 KCNMB4 AMIGO3 AMIGO3 ATP2B4 ATP2B4 CACNB3 CACNB3 TRPV1 TRPV1 NRXN3 NRXN3 AMBP AMBP KCNIP4 KCNIP4 PKP2 PKP2 MCUB MCUB TSPAN13 TSPAN13 WNK3 WNK3 PRSS8 PRSS8 AKAP9 AKAP9 GRM3 GRM3 REM2 REM2 SGK1 SGK1 LRRC52 LRRC52 PCSK9 PCSK9 G1RWW4_NOMLE G1RWW4_NOMLE STX7 STX7 TMPRSS3 TMPRSS3 PACSIN3 PACSIN3 KCNK2 KCNK2 FLNA FLNA SCLT1 SCLT1 PDZD4 PDZD4 RASA1 RASA1 POTEA POTEA LRRC55 LRRC55 PRKG1 PRKG1 CNTD1 CNTD1 WNK4 WNK4 CFTR CFTR FXYD5 FXYD5 FXYD1 FXYD1 FXYD3 FXYD3 G1RJA2_NOMLE G1RJA2_NOMLE TNNI3 TNNI3 SLC9A3R1 SLC9A3R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (386 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
CHRNA7Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (358 aa)
PDZD3PDZ domain containing 3. (549 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
GRM2Glutamate metabotropic receptor 2. (873 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (529 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
CABP2Uncharacterized protein. (226 aa)
CABP4Calcium binding protein 4. (275 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (254 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (424 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (271 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
G1QZ78_NOMLEUncharacterized protein. (162 aa)
NRXN2Neurexin 2. (1626 aa)
ABCC9ATP binding cassette subfamily C member 9. (1567 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (278 aa)
CRISP1Cysteine rich secretory protein 1; Belongs to the CRISP family. (249 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
STX8Syntaxin 8. (236 aa)
SLC30A1Solute carrier family 30 member 1. (507 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1425 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
PRKCZProtein kinase C zeta. (507 aa)
KCNIP3Uncharacterized protein. (231 aa)
SNTA1Syntrophin alpha 1. (501 aa)
LRRC38Leucine rich repeat containing 38. (294 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
ENSNLEP00000048122Uncharacterized protein. (73 aa)
WNK2WNK lysine deficient protein kinase 2. (1977 aa)
CABP5Calcium binding protein 5. (173 aa)
SUMO1Small ubiquitin-related modifier. (88 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (320 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (404 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
WNK1WNK lysine deficient protein kinase 1. (2833 aa)
ENSNLEP00000045038t-SNARE coiled-coil homology domain-containing protein. (226 aa)
LOC10058324514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa)
COMMD1Copper metabolism domain containing 1. (190 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
KCNIP2Uncharacterized protein. (286 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
LOC100590514Uncharacterized protein. (130 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (913 aa)
VAMP8V-SNARE coiled-coil homology domain-containing protein. (116 aa)
CRISP2Cysteine rich secretory protein 2; Belongs to the CRISP family. (277 aa)
STIM2Stromal interaction molecule 2. (841 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
NRXN1Neurexin 1. (1547 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (131 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (241 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
ENSNLEP00000035652Uncharacterized protein; Belongs to the calmodulin family. (123 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (862 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (101 aa)
STX1At-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (243 aa)
LOC101179053Small ubiquitin-related modifier. (94 aa)
KCNMB3Uncharacterized protein. (329 aa)
VAMP5Vesicle associated membrane protein 5. (116 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
ENSNLEP00000031915Ubiquitin-like domain-containing protein. (93 aa)
MUSTN1Uncharacterized protein. (87 aa)
ENSAUncharacterized protein. (187 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (409 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (522 aa)
ENSNLEP00000031077Neur_chan_LBD domain-containing protein. (158 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
LOC100582441Uncharacterized protein. (826 aa)
ENSNLEP00000029822FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (86 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
STOML1Stomatin like 1. (400 aa)
STIM1Stromal interaction molecule 1. (818 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa)
CABP1Uncharacterized protein. (304 aa)
PRSS41Serine protease 41; Belongs to the peptidase S1 family. (318 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (221 aa)
HPCAL4Uncharacterized protein. (85 aa)
FXYD4FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)
ENSNLEP00000026357Uncharacterized protein. (197 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
ENSNLEP00000025820Rad60-SLD domain-containing protein. (80 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (800 aa)
STIMATEUncharacterized protein. (308 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (504 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (444 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
NRXN3Uncharacterized protein. (1061 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (312 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (250 aa)
PKP2Uncharacterized protein. (841 aa)
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (336 aa)
TSPAN13Tetraspanin 13; Belongs to the tetraspanin (TM4SF) family. (204 aa)
WNK3WNK lysine deficient protein kinase 3. (1800 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (343 aa)
AKAP9A-kinase anchoring protein 9. (3896 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
REM2RRAD and GEM like GTPase 2. (340 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
LRRC52Leucine rich repeat containing 52. (313 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (693 aa)
G1RWW4_NOMLEUncharacterized protein. (241 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (436 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
FLNAFilamin A. (2626 aa)
SCLT1Sodium channel and clathrin linker 1. (688 aa)
PDZD4PDZ domain containing 4. (756 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
POTEAANK_REP_REGION domain-containing protein. (472 aa)
LRRC55Leucine rich repeat containing 55. (341 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
CNTD1Cyclin N-terminal domain containing 1. (330 aa)
WNK4WNK lysine deficient protein kinase 4. (1037 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa)
FXYD5FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (107 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (70 aa)
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (143 aa)
G1RJA2_NOMLEIGv domain-containing protein. (221 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
SLC9A3R1Uncharacterized protein. (276 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (32%) [HD]