106 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AR	Uncharacterized protein. (392 aa)
	G1QJ30_NOMLE	Uncharacterized protein. (363 aa)
	VTI1B	Vesicle transport through interaction with t-SNAREs 1B. (232 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
	CLN3	Battenin. (384 aa)
	ZDHHC2	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (367 aa)
	ABI3	ABI family member 3. (332 aa)
	NUMB	NUMB endocytic adaptor protein. (650 aa)
	MRAP	Melanocortin 2 receptor accessory protein. (172 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
	CNST	Consortin, connexin sorting protein. (725 aa)
	RAMP3	Receptor activity modifying protein 3. (148 aa)
	PLS1	Plastin 1. (629 aa)
	STAC	SH3 and cysteine rich domain. (402 aa)
	TREM2	Ig-like domain-containing protein. (222 aa)
	ANXA13	Annexin. (357 aa)
	VPS4A	Uncharacterized protein; Belongs to the AAA ATPase family. (506 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa)
	APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (674 aa)
	EPHA2	EPH receptor A2. (976 aa)
	ARHGEF16	Uncharacterized protein. (509 aa)
	LRRC15	Leucine rich repeat containing 15. (587 aa)
	LYPD1	LY6/PLAUR domain containing 1. (141 aa)
	TMBIM1	Uncharacterized protein; Belongs to the BI1 family. (137 aa)
	VIL1	Villin 1. (827 aa)
	R3HDM1	R3H domain containing 1. (1100 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1050 aa)
	LOC100592336	PH_3 domain-containing protein. (247 aa)
	BCL2L1	BCL2 like 1. (217 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	STX8	Syntaxin 8. (236 aa)
	GBP1	Guanylate binding protein 1. (590 aa)
	NKD2	EF-hand domain-containing protein. (388 aa)
	ZDHHC7	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (345 aa)
	CNPY4	Canopy FGF signaling regulator 4. (245 aa)
	CLIP3	CAP-Gly domain containing linker protein 3. (504 aa)
	EPHA3	EPH receptor A3. (983 aa)
	CIB1	Uncharacterized protein. (187 aa)
	MRAP2	Melanocortin 2 receptor accessory protein 2. (205 aa)
	LGALS3	Galectin. (250 aa)
	ZDHHC5	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (715 aa)
	PTPN9	Protein tyrosine phosphatase non-receptor type 9. (502 aa)
	GOPC	PDZ domain-containing protein. (462 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	STX7	Syntaxin 7; Belongs to the syntaxin family. (261 aa)
	CSK	Tyrosine-protein kinase. (274 aa)
	MMP14	Matrix metallopeptidase 14. (586 aa)
	EPM2A	EPM2A glucan phosphatase, laforin. (331 aa)
	HECTD1	HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
	STX4	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	WNK3	WNK lysine deficient protein kinase 3. (1800 aa)
	DAB2	DAB adaptor protein 2. (749 aa)
	AGR2	Anterior gradient 2, protein disulphide isomerase family member. (189 aa)
	PKDCC	Protein kinase domain containing, cytoplasmic. (493 aa)
	PRKCE	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
	STAC3	SH3 and cysteine rich domain 3. (364 aa)
	G1S7S9_NOMLE	PDZ domain-containing protein. (332 aa)
	CSRP3	Cysteine and glycine rich protein 3. (194 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
	KIF5B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
	NHLRC1	NHL repeat containing E3 ubiquitin protein ligase 1. (395 aa)
	AKAP5	A-kinase anchoring protein 5. (427 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
	GPER1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	PRNP	Major prion protein; Belongs to the prion family. (253 aa)
	RHOQ	Uncharacterized protein. (190 aa)
	DPP10	Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (800 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	ENSNLEP00000026357	Uncharacterized protein. (197 aa)
	ENSNLEP00000027513	Uncharacterized protein. (154 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa)
	STX3	Syntaxin 3; Belongs to the syntaxin family. (251 aa)
	PID1	Uncharacterized protein. (97 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	ARHGAP44	Rho GTPase activating protein 44. (792 aa)
	GRIPAP1	GRIP1 associated protein 1. (823 aa)
	ATP2C1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (973 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
	ARF6	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	RANGRF	RAN guanine nucleotide release factor. (186 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (299 aa)
	ENSNLEP00000032399	Uncharacterized protein. (628 aa)
	ENSNLEP00000033007	Uncharacterized protein; Belongs to the actin family. (312 aa)
	SORBS1	Uncharacterized protein. (1293 aa)
	ENSNLEP00000035481	Uncharacterized protein. (73 aa)
	EGFR	Receptor protein-tyrosine kinase. (1206 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
	RHOG	Ras homolog family member G. (191 aa)
	ENSNLEP00000036861	Uncharacterized protein. (119 aa)
	PPP1R9B	Protein phosphatase 1 regulatory subunit 9B. (813 aa)
	ACTB	Uncharacterized protein. (363 aa)
	LRP1	LDL receptor related protein 1. (4219 aa)
	NRXN1	Neurexin 1. (1547 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2289 aa)
	R3HDM2	R3H domain containing 2. (1033 aa)
	LOC100593010	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
	PICALM	Phosphatidylinositol binding clathrin assembly protein. (669 aa)
	VAMP8	V-SNARE coiled-coil homology domain-containing protein. (116 aa)
	EPHB2	EPH receptor B2. (1015 aa)
	ENSNLEP00000045038	t-SNARE coiled-coil homology domain-containing protein. (226 aa)
	EZR	Ezrin. (586 aa)
	RACK1	WD_REPEATS_REGION domain-containing protein. (320 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	TMEM59	Transmembrane protein 59. (311 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	AKT1	ENSNLEP00000038010	ENSNLEP00000028045	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.636
ACTB	AR	ENSNLEP00000038010	ENSNLEP00000000665	Uncharacterized protein.	Uncharacterized protein.	0.496
ACTB	BCL2L1	ENSNLEP00000038010	ENSNLEP00000011718	Uncharacterized protein.	BCL2 like 1.	0.486
ACTB	CLTC	ENSNLEP00000038010	ENSNLEP00000001008	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.455
ACTB	EGFR	ENSNLEP00000038010	ENSNLEP00000035792	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.517
ACTB	EZR	ENSNLEP00000038010	ENSNLEP00000045659	Uncharacterized protein.	Ezrin.	0.521
ACTB	ITGB1	ENSNLEP00000038010	ENSNLEP00000030750	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.612
ACTB	TGFB1	ENSNLEP00000038010	ENSNLEP00000016659	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.485
ACTB	TNF	ENSNLEP00000038010	ENSNLEP00000047690	Uncharacterized protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.551
AKAP5	DLG1	ENSNLEP00000022983	ENSNLEP00000028840	A-kinase anchoring protein 5.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.764
AKT1	ACTB	ENSNLEP00000028045	ENSNLEP00000038010	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.636
AKT1	APPL1	ENSNLEP00000028045	ENSNLEP00000008854	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.931
AKT1	AR	ENSNLEP00000028045	ENSNLEP00000000665	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.745
AKT1	ARF6	ENSNLEP00000028045	ENSNLEP00000032176	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.562
AKT1	BCL2L1	ENSNLEP00000028045	ENSNLEP00000011718	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 like 1.	0.969
AKT1	CSK	ENSNLEP00000028045	ENSNLEP00000017774	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.474
AKT1	DAB2	ENSNLEP00000028045	ENSNLEP00000019957	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	DAB adaptor protein 2.	0.492
AKT1	EGFR	ENSNLEP00000028045	ENSNLEP00000035792	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.642
AKT1	ENSNLEP00000027513	ENSNLEP00000028045	ENSNLEP00000027513	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.562
AKT1	ENSNLEP00000032399	ENSNLEP00000028045	ENSNLEP00000032399	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.514

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