node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADIPOQ | IL10 | ENSNLEP00000008120 | ENSNLEP00000033936 | Adiponectin, C1Q and collagen domain containing. | Interleukin 10. | 0.633 |
ADIPOQ | PPARG | ENSNLEP00000008120 | ENSNLEP00000037002 | Adiponectin, C1Q and collagen domain containing. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.797 |
CDKN1B | PTEN | ENSNLEP00000024488 | ENSNLEP00000014741 | Uncharacterized protein. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.630 |
CNN1 | MYOCD | ENSNLEP00000015309 | ENSNLEP00000046846 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | Myocardin. | 0.633 |
CNN1 | TPM1 | ENSNLEP00000015309 | ENSNLEP00000033303 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | Uncharacterized protein; Belongs to the tropomyosin family. | 0.494 |
GNA12 | GNA13 | ENSNLEP00000027704 | ENSNLEP00000018099 | G protein subunit alpha 12. | G protein subunit alpha 13. | 0.989 |
GNA13 | GNA12 | ENSNLEP00000018099 | ENSNLEP00000027704 | G protein subunit alpha 13. | G protein subunit alpha 12. | 0.989 |
IL10 | ADIPOQ | ENSNLEP00000033936 | ENSNLEP00000008120 | Interleukin 10. | Adiponectin, C1Q and collagen domain containing. | 0.633 |
IL10 | PPARG | ENSNLEP00000033936 | ENSNLEP00000037002 | Interleukin 10. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.557 |
IL10 | PTEN | ENSNLEP00000033936 | ENSNLEP00000014741 | Interleukin 10. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.518 |
IL10 | TGFB3 | ENSNLEP00000033936 | ENSNLEP00000020116 | Interleukin 10. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.454 |
MEF2C | MYOCD | ENSNLEP00000034337 | ENSNLEP00000046846 | Myocyte enhancer factor 2C. | Myocardin. | 0.602 |
MYOCD | CNN1 | ENSNLEP00000046846 | ENSNLEP00000015309 | Myocardin. | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | 0.633 |
MYOCD | MEF2C | ENSNLEP00000046846 | ENSNLEP00000034337 | Myocardin. | Myocyte enhancer factor 2C. | 0.602 |
MYOCD | PTEN | ENSNLEP00000046846 | ENSNLEP00000014741 | Myocardin. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.479 |
PDCD4 | PTEN | ENSNLEP00000018912 | ENSNLEP00000014741 | Programmed cell death 4. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.584 |
PDCD4 | TPM1 | ENSNLEP00000018912 | ENSNLEP00000033303 | Programmed cell death 4. | Uncharacterized protein; Belongs to the tropomyosin family. | 0.502 |
PPARG | ADIPOQ | ENSNLEP00000037002 | ENSNLEP00000008120 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Adiponectin, C1Q and collagen domain containing. | 0.797 |
PPARG | IL10 | ENSNLEP00000037002 | ENSNLEP00000033936 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Interleukin 10. | 0.557 |
PPARG | PTEN | ENSNLEP00000037002 | ENSNLEP00000014741 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.640 |