STRINGSTRING
CCDC142 CCDC142 ANO6 ANO6 TEK TEK PDCD4 PDCD4 FASLG FASLG TNFAIP3 TNFAIP3 PAK4 PAK4 GATA2 GATA2 IL4 IL4 ABL1 ABL1 ICAM1 ICAM1 GATA3 GATA3 RAMP2 RAMP2 SEMA5A SEMA5A TERT TERT GAS6 GAS6 SCG2 SCG2 LOC100592336 LOC100592336 ECSCR ECSCR MAPK7 MAPK7 SERPINE1 SERPINE1 PLCG1 PLCG1 ITGA4 ITGA4 FGA FGA FGB FGB CD160 CD160 FGF21 FGF21 CDH5 CDH5 BRAF BRAF ANGPTL4 ANGPTL4 G1QLB3_NOMLE G1QLB3_NOMLE RGCC RGCC TNIP2 TNIP2 TNF TNF AKR1C3 AKR1C3 CD40LG CD40LG KDR KDR THBS1 THBS1 XBP1 XBP1 NFE2L2 NFE2L2 FGG FGG ANGPT1 ANGPT1 LOC100593010 LOC100593010 NDNF NDNF IL10 IL10 CD40 CD40 KRIT1 KRIT1 GPER1 GPER1 PRKCI PRKCI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCDC142Coiled-coil domain containing 142. (749 aa)
ANO6Anoctamin. (931 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
PDCD4Programmed cell death 4. (470 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
PAK4Non-specific serine/threonine protein kinase. (595 aa)
GATA2GATA binding protein 2. (480 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (135 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
ICAM1Intercellular adhesion molecule 1. (531 aa)
GATA3GATA binding protein 3. (444 aa)
RAMP2Receptor activity modifying protein 2. (180 aa)
SEMA5ASemaphorin 5A. (1074 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (983 aa)
GAS6Growth arrest specific 6. (679 aa)
SCG2Secretogranin II. (542 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
ECSCRUncharacterized protein. (106 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
FGAFibrinogen alpha chain. (863 aa)
FGBFibrinogen beta chain. (491 aa)
CD160CD160 molecule. (181 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (687 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
ANGPTL4Angiopoietin like 4. (379 aa)
G1QLB3_NOMLEC-C motif chemokine. (138 aa)
RGCCRegulator of cell cycle. (137 aa)
TNIP2CCHC NOA-type domain-containing protein. (322 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (323 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
THBS1Thrombospondin 1. (1173 aa)
XBP1BZIP domain-containing protein. (376 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (607 aa)
FGGFibrinogen gamma chain. (463 aa)
ANGPT1Angiopoietin 1. (498 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
IL10Interleukin 10. (178 aa)
CD40TNFR-Cys domain-containing protein. (219 aa)
KRIT1Uncharacterized protein. (736 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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