STRINGSTRING
IVNS1ABP IVNS1ABP ENSNLEP00000034296 ENSNLEP00000034296 ENSNLEP00000032876 ENSNLEP00000032876 ENSNLEP00000032223 ENSNLEP00000032223 KDM1A KDM1A URI1 URI1 ENSNLEP00000031386 ENSNLEP00000031386 ENSNLEP00000031088 ENSNLEP00000031088 YBX3 YBX3 ENSNLEP00000029188 ENSNLEP00000029188 PPIF PPIF ENSNLEP00000028374 ENSNLEP00000028374 DDX3X DDX3X ARHGEF2 ARHGEF2 AKT1 AKT1 ENSNLEP00000027342 ENSNLEP00000027342 ENSNLEP00000026972 ENSNLEP00000026972 LOC100587940 LOC100587940 DDIAS DDIAS USP47 USP47 PINK1 PINK1 FAM167A FAM167A ZNF385A ZNF385A G1SB25_NOMLE G1SB25_NOMLE PTGS2 PTGS2 MAPK8IP1 MAPK8IP1 LRRK2 LRRK2 CD44 CD44 CLU CLU BAG5 BAG5 CCAR2 CCAR2 TRIAP1 TRIAP1 CREB3L1 CREB3L1 SNAI2 SNAI2 HELLS HELLS CDKN2D CDKN2D RTKN2 RTKN2 SIRT1 SIRT1 EPO EPO MUC1 MUC1 WFS1 WFS1 PRKN PRKN SOD2 SOD2 ACKR3 ACKR3 CD74 CD74 MCL1 MCL1 TRAP1 TRAP1 BCL2L1 BCL2L1 TPT1 TPT1 MAPK7 MAPK7 NME5 NME5 SNAI1 SNAI1 MMP9 MMP9 OPA1 OPA1 BCL2L10 BCL2L10 NDUFA13 NDUFA13 TMEM161A TMEM161A PARL PARL SFRP2 SFRP2 ATAD5 ATAD5 SYVN1 SYVN1 ELL3 ELL3 BCL2L12 BCL2L12 PIK3CB PIK3CB CREB3 CREB3 PPIA PPIA HDAC1 HDAC1 GRINA GRINA PLAUR PLAUR MARCHF7 MARCHF7 BDKRB2 BDKRB2 PDX1 PDX1 NOC2L NOC2L TXNDC12 TXNDC12 HIF1A HIF1A SRC SRC ENSNLEP00000046123 ENSNLEP00000046123 PTTG1IP PTTG1IP ENSNLEP00000044100 ENSNLEP00000044100 SELENOS SELENOS ARMC10 ARMC10 ENSNLEP00000043421 ENSNLEP00000043421 PARK7 PARK7 NDUFS3 NDUFS3 XBP1 XBP1 NFE2L2 NFE2L2 LOC100595123 LOC100595123 ENSNLEP00000040637 ENSNLEP00000040637 NONO NONO CLUL1 CLUL1 HTRA2 HTRA2 VDAC2 VDAC2 ENSNLEP00000039074 ENSNLEP00000039074 HYOU1 HYOU1 CXCL12 CXCL12 ENSNLEP00000038644 ENSNLEP00000038644 ENSNLEP00000037210 ENSNLEP00000037210 BID BID RRM2B RRM2B BCL2 BCL2 TRIM32 TRIM32
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IVNS1ABPInfluenza virus NS1A binding protein. (642 aa)
ENSNLEP00000034296DJ-1_PfpI domain-containing protein. (133 aa)
ENSNLEP00000032876Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa)
ENSNLEP00000032223TCTP domain-containing protein; Belongs to the TCTP family. (191 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (759 aa)
URI1URI1 prefoldin like chaperone. (501 aa)
ENSNLEP00000031386TCTP domain-containing protein; Belongs to the TCTP family. (195 aa)
ENSNLEP00000031088Protein kinase domain-containing protein. (557 aa)
YBX3Y-box binding protein 3. (344 aa)
ENSNLEP00000029188Uncharacterized protein. (60 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa)
ENSNLEP00000028374PHD domain-containing protein. (263 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (704 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
ENSNLEP00000027342Uncharacterized protein. (468 aa)
ENSNLEP00000026972RRM domain-containing protein. (153 aa)
LOC100587940Uncharacterized protein. (704 aa)
DDIASDNA damage induced apoptosis suppressor. (998 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
PINK1Protein kinase domain-containing protein. (563 aa)
FAM167AFamily with sequence similarity 167 member A. (214 aa)
ZNF385AZinc finger protein 385A. (372 aa)
G1SB25_NOMLETCTP domain-containing protein; Belongs to the TCTP family. (152 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (665 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
CD44CD44 molecule (Indian blood group). (742 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (448 aa)
BAG5BCL2 associated athanogene 5. (482 aa)
CCAR2Cell cycle and apoptosis regulator 2. (923 aa)
TRIAP1TP53 regulated inhibitor of apoptosis 1. (76 aa)
CREB3L1BZIP domain-containing protein. (467 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
HELLSHelicase, lymphoid specific. (883 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
RTKN2Rhotekin 2. (609 aa)
SIRT1Sirtuin 1. (734 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
MUC1Mucin 1, cell surface associated. (483 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (437 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
CD74CD74 molecule. (296 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (350 aa)
TRAP1TNF receptor associated protein 1. (704 aa)
BCL2L1BCL2 like 1. (217 aa)
TPT1Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (198 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
NME5NME/NM23 family member 5; Belongs to the NDK family. (212 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
MMP9Matrix metallopeptidase 9. (692 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (957 aa)
BCL2L10BCL2 like 10. (231 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
TMEM161AUncharacterized protein. (455 aa)
PARLPresenilin associated rhomboid like. (379 aa)
SFRP2Secreted frizzled related protein 2. (280 aa)
ATAD5ATPase family AAA domain containing 5. (1823 aa)
SYVN1Synoviolin 1. (617 aa)
ELL3Elongation factor for RNA polymerase II 3. (397 aa)
BCL2L12BCL2 like 12. (324 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
GRINAUncharacterized protein; Belongs to the BI1 family. (116 aa)
PLAURPlasminogen activator, urokinase receptor. (335 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (703 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (386 aa)
PDX1Pancreatic and duodenal homeobox 1. (283 aa)
NOC2LUncharacterized protein. (707 aa)
TXNDC12Thioredoxin domain containing 12. (172 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
SRCTyrosine-protein kinase. (537 aa)
ENSNLEP00000046123Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa)
PTTG1IPPTTG1 interacting protein. (162 aa)
ENSNLEP00000044100Inhibitor of growth protein. (229 aa)
SELENOSUncharacterized protein. (218 aa)
ARMC10Armadillo repeat containing 10. (347 aa)
ENSNLEP00000043421Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (393 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa)
XBP1BZIP domain-containing protein. (376 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (607 aa)
LOC100595123Uncharacterized protein. (262 aa)
ENSNLEP00000040637Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
NONONon-POU domain containing octamer binding. (463 aa)
CLUL1Clusterin; Belongs to the clusterin family. (518 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
VDAC2Voltage dependent anion channel 2. (297 aa)
ENSNLEP00000039074Uncharacterized protein. (150 aa)
HYOU1Hypoxia up-regulated 1. (956 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
ENSNLEP00000038644SH3 domain-containing protein. (713 aa)
ENSNLEP00000037210PHD domain-containing protein. (253 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (214 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (355 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TRIM32Tripartite motif containing 32. (653 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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