STRINGSTRING
CAPN2 CAPN2 AFAP1 AFAP1 FAT1 FAT1 IGF2R IGF2R ARPC1B ARPC1B IRF2 IRF2 RND3 RND3 CTTN CTTN LOC100587124 LOC100587124 LOC101179385 LOC101179385 PRUNE1 PRUNE1 NEXN NEXN ARHGAP26 ARHGAP26 HCK HCK SLC9A1 SLC9A1 LOC100592336 LOC100592336 G1RDL6_NOMLE G1RDL6_NOMLE ARHGAP24 ARHGAP24 JAK2 JAK2 ITGA3 ITGA3 CD151 CD151 ASAP3 ASAP3 PEAK1 PEAK1 HSPG2 HSPG2 SCARB2 SCARB2 EPHA2 EPHA2 PTPRA PTPRA MCAM MCAM FAM107A FAM107A FLNB FLNB TNS1 TNS1 RDX RDX CASS4 CASS4 YES1 YES1 CORO1C CORO1C LPP LPP YWHAB YWHAB CORO1B CORO1B TGM2 TGM2 ITGA4 ITGA4 MAPRE2 MAPRE2 LIMD1 LIMD1 ARL2 ARL2 KRAS KRAS RRAS RRAS MRC2 MRC2 TNS3 TNS3 ACTN2 ACTN2 CD9 CD9 ZYX ZYX MAP2K2 MAP2K2 RALA RALA NUMB NUMB PEAK3 PEAK3 VASP VASP ATP6V0A2 ATP6V0A2 MAPK3 MAPK3 TNS4 TNS4 PLAUR PLAUR NECTIN2 NECTIN2 FBLN7 FBLN7 CNN2 CNN2 GRB7 GRB7 STARD8 STARD8 FLT1 FLT1 MSN MSN NPM1 NPM1 RPLP0 RPLP0 GNB2 GNB2 TRIP6 TRIP6 TLN2 TLN2 ICAM1 ICAM1 FES FES ITGA8 ITGA8 FLNC FLNC CNN1 CNN1 CALR CALR CORO2B CORO2B CSPG4 CSPG4 ADGRE5 ADGRE5 YWHAQ YWHAQ L1CAM L1CAM FLNA FLNA SYNE2 SYNE2 ARF1 ARF1 PAK4 PAK4 DDR2 DDR2 MMP14 MMP14 PRAG1 PRAG1 EFS EFS JAK1 JAK1 AKAP12 AKAP12 LMLN LMLN SORBS3 SORBS3 RAC1 RAC1 LMO7 LMO7 PTK2B PTK2B DAB2 DAB2 AVIL AVIL PARVA PARVA RRAS2 RRAS2 TNS2 TNS2 LIMA1 LIMA1 SENP1 SENP1 TWF1 TWF1 PTPRC PTPRC CSRP1 CSRP1 ERAS ERAS LOC100588496 LOC100588496 CDH13 CDH13 ARL14EP ARL14EP ENSNLEP00000024646 ENSNLEP00000024646 NRP1 NRP1 SVIL SVIL PARVB PARVB ENG ENG ENSNLEP00000025403 ENSNLEP00000025403 CSRP2 CSRP2 LOC100599403 LOC100599403 ZFYVE21 ZFYVE21 ENSNLEP00000026050 ENSNLEP00000026050 ANXA5 ANXA5 ARL14EPL ARL14EPL MAPK1 MAPK1 ENSNLEP00000027420 ENSNLEP00000027420 ENSNLEP00000027802 ENSNLEP00000027802 ENSNLEP00000027935 ENSNLEP00000027935 ARHGEF2 ARHGEF2 DNM2 DNM2 EVL EVL ALCAM ALCAM ENSNLEP00000029090 ENSNLEP00000029090 ENSNLEP00000029280 ENSNLEP00000029280 FHL1 FHL1 PDLIM7 PDLIM7 ADAM9 ADAM9 NHS NHS LIMS1 LIMS1 ENSNLEP00000031566 ENSNLEP00000031566 PVR PVR LCP1 LCP1 ENSNLEP00000032480 ENSNLEP00000032480 UBOX5 UBOX5 ENSNLEP00000032709 ENSNLEP00000032709 ENSNLEP00000032809 ENSNLEP00000032809 ARHGAP22 ARHGAP22 PPP1R12A PPP1R12A FLRT2 FLRT2 TLN1 TLN1 LAYN LAYN LIMS2 LIMS2 PTK2 PTK2 SORBS1 SORBS1 REXO2 REXO2 DLC1 DLC1 SNAP23 SNAP23 LMLN2 LMLN2 FERMT2 FERMT2 ENSNLEP00000036047 ENSNLEP00000036047 MAP2K1 MAP2K1 RHOG RHOG ENSNLEP00000036074 ENSNLEP00000036074 ITGA6 ITGA6 ENSNLEP00000036988 ENSNLEP00000036988 ANXA6 ANXA6 ACTN3 ACTN3 LRP1 LRP1 ENSNLEP00000038443 ENSNLEP00000038443 MPRIP MPRIP LOC100584516 LOC100584516 ENSNLEP00000038791 ENSNLEP00000038791 ENSNLEP00000038911 ENSNLEP00000038911 ENSNLEP00000039230 ENSNLEP00000039230 THSD1 THSD1 MAP4K4 MAP4K4 NEDD9 NEDD9 ARHGEF7 ARHGEF7 ENSNLEP00000039968 ENSNLEP00000039968 GIT2 GIT2 GSN GSN LOC100593010 LOC100593010 FHL2 FHL2 ENSNLEP00000041044 ENSNLEP00000041044 RHOB RHOB EFNB2 EFNB2 BCAR1 BCAR1 GIT1 GIT1 PIP5K1A PIP5K1A ENSNLEP00000041829 ENSNLEP00000041829 BCAR3 BCAR3 ENSNLEP00000041962 ENSNLEP00000041962 RSU1 RSU1 RAC2 RAC2 CNN3 CNN3 ENSNLEP00000042609 ENSNLEP00000042609 ENSNLEP00000042936 ENSNLEP00000042936 YWHAE YWHAE ENSNLEP00000043511 ENSNLEP00000043511 FZD2 FZD2 LOC100583245 LOC100583245 FOCAD FOCAD PIP5K1C PIP5K1C PPFIBP1 PPFIBP1 EZR EZR MARCKS MARCKS PFN1-2 PFN1-2 SYNPO2 SYNPO2 LOC100593698 LOC100593698 PXN PXN ENSNLEP00000048155 ENSNLEP00000048155 SRC SRC ENAH ENAH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAPN2Calpain 2; Belongs to the peptidase C2 family. (660 aa)
AFAP1Actin filament associated protein 1. (804 aa)
FAT1FAT atypical cadherin 1. (4561 aa)
IGF2RInsulin like growth factor 2 receptor. (2458 aa)
ARPC1BWD_REPEATS_REGION domain-containing protein. (598 aa)
IRF2Interferon regulatory factor. (349 aa)
RND3Rho family GTPase 3. (244 aa)
CTTNSH3 domain-containing protein. (549 aa)
LOC100587124Protein S100; Belongs to the S-100 family. (101 aa)
LOC101179385Protein S100; Belongs to the S-100 family. (101 aa)
PRUNE1Prune exopolyphosphatase 1. (453 aa)
NEXNNexilin F-actin binding protein. (675 aa)
ARHGAP26Uncharacterized protein. (417 aa)
HCKTyrosine-protein kinase. (525 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
G1RDL6_NOMLEUncharacterized protein. (279 aa)
ARHGAP24Rho GTPase activating protein 24. (748 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1050 aa)
CD151Tetraspanin. (249 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (903 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1747 aa)
HSPG2Heparan sulfate proteoglycan 2. (4123 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (443 aa)
EPHA2EPH receptor A2. (976 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
MCAMMelanoma cell adhesion molecule. (625 aa)
FAM107AFamily with sequence similarity 107 member A. (175 aa)
FLNBFilamin B. (2585 aa)
TNS1Tensin 1. (1696 aa)
RDXRadixin. (604 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
YES1Tyrosine-protein kinase. (519 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (444 aa)
LPPLIM domain containing preferred translocation partner in lipoma. (612 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (481 aa)
TGM2Transglutaminase 2. (668 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (327 aa)
LIMD1LIM domains containing 1. (676 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (183 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
RRASRAS related. (217 aa)
MRC2Mannose receptor C type 2. (1328 aa)
TNS3Tensin 3. (1402 aa)
ACTN2Actinin alpha 2. (854 aa)
CD9Tetraspanin. (228 aa)
ZYXLIM zinc-binding domain-containing protein. (312 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (383 aa)
RALARAS like proto-oncogene A. (206 aa)
NUMBNUMB endocytic adaptor protein. (650 aa)
PEAK3PEAK family member 3. (465 aa)
VASPVasodilator stimulated phosphoprotein. (341 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
TNS4Tensin 4. (703 aa)
PLAURPlasminogen activator, urokinase receptor. (335 aa)
NECTIN2Uncharacterized protein. (356 aa)
FBLN7Fibulin 7. (439 aa)
CNN2Uncharacterized protein. (221 aa)
GRB7Growth factor receptor bound protein 7. (476 aa)
STARD8StAR related lipid transfer domain containing 8. (1108 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
MSNMoesin. (566 aa)
NPM1Nucleophosmin 1. (294 aa)
RPLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
GNB2G protein subunit beta 2. (325 aa)
TRIP6Thyroid hormone receptor interactor 6. (447 aa)
TLN2Uncharacterized protein. (2289 aa)
ICAM1Intercellular adhesion molecule 1. (531 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (828 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1048 aa)
FLNCFilamin C. (2560 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (304 aa)
CALRCalreticulin. (417 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (413 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2170 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (783 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (253 aa)
L1CAML1 cell adhesion molecule. (1174 aa)
FLNAFilamin A. (2626 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6793 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
PAK4Non-specific serine/threonine protein kinase. (595 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
MMP14Matrix metallopeptidase 14. (586 aa)
PRAG1PEAK1 related, kinase-activating pseudokinase 1. (1362 aa)
EFSEmbryonal Fyn-associated substrate. (561 aa)
JAK1Tyrosine-protein kinase. (1149 aa)
AKAP12A-kinase anchoring protein 12. (1779 aa)
LMLNLeishmanolysin-like peptidase. (648 aa)
SORBS3Sorbin and SH3 domain containing 3. (676 aa)
RAC1Rac family small GTPase 1. (187 aa)
LMO7LIM domain 7. (1667 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (871 aa)
DAB2DAB adaptor protein 2. (749 aa)
AVILAdvillin. (819 aa)
PARVAParvin alpha. (345 aa)
RRAS2RAS related 2. (204 aa)
TNS2Tensin 2. (1361 aa)
LIMA1LIM domain and actin binding 1. (760 aa)
SENP1SUMO specific peptidase 1. (645 aa)
TWF1Twinfilin actin binding protein 1. (384 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1304 aa)
CSRP1Cysteine and glycine rich protein 1. (193 aa)
ERASES cell expressed Ras. (233 aa)
LOC100588496FERM domain-containing protein. (263 aa)
CDH13Cadherin 13. (760 aa)
ARL14EPADP ribosylation factor like GTPase 14 effector protein. (260 aa)
ENSNLEP00000024646Uncharacterized protein. (137 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (901 aa)
SVILSupervillin. (1949 aa)
PARVBParvin beta. (396 aa)
ENGEndoglin. (658 aa)
ENSNLEP00000025403Uncharacterized protein. (265 aa)
CSRP2Uncharacterized protein. (243 aa)
LOC100599403PIPK domain-containing protein. (591 aa)
ZFYVE21Zinc finger FYVE-type containing 21. (247 aa)
ENSNLEP0000002605014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (241 aa)
ANXA5Annexin. (318 aa)
ARL14EPLADP ribosylation factor like GTPase 14 effector protein like. (152 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
ENSNLEP00000027420Uncharacterized protein. (264 aa)
ENSNLEP00000027802Uncharacterized protein. (223 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (770 aa)
EVLEnah/Vasp-like. (458 aa)
ALCAMActivated leukocyte cell adhesion molecule. (590 aa)
ENSNLEP00000029090Uncharacterized protein. (278 aa)
ENSNLEP0000002928014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (230 aa)
FHL1Four and a half LIM domains 1. (323 aa)
PDLIM7Uncharacterized protein. (368 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
NHSNHS actin remodeling regulator. (1630 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (397 aa)
ENSNLEP00000031566HP domain-containing protein. (71 aa)
PVRPVR cell adhesion molecule. (372 aa)
LCP1Lymphocyte cytosolic protein 1. (630 aa)
ENSNLEP0000003248060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (293 aa)
UBOX5RING-type domain-containing protein. (490 aa)
ENSNLEP00000032709Profilin; Belongs to the profilin family. (120 aa)
ENSNLEP00000032809Calponin-homology (CH) domain-containing protein. (332 aa)
ARHGAP22Rho GTPase activating protein 22. (715 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
TLN1Talin 1. (2542 aa)
LAYNLayilin. (382 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (365 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
SORBS1Uncharacterized protein. (1293 aa)
REXO2RNA exonuclease 2. (237 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
LMLN2Leishmanolysin-like peptidase. (787 aa)
FERMT2Fermitin family member 2. (693 aa)
ENSNLEP00000036047Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (308 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
RHOGRas homolog family member G. (191 aa)
ENSNLEP00000036074Uncharacterized protein. (393 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ENSNLEP00000036988Nucleoplasmin domain-containing protein. (224 aa)
ANXA6Annexin. (673 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (922 aa)
LRP1LDL receptor related protein 1. (4219 aa)
ENSNLEP00000038443Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (154 aa)
MPRIPMyosin phosphatase Rho interacting protein. (997 aa)
LOC100584516Uncharacterized protein. (306 aa)
ENSNLEP00000038791Uncharacterized protein. (63 aa)
ENSNLEP00000038911RL10P_insert domain-containing protein. (305 aa)
ENSNLEP00000039230RL10P_insert domain-containing protein. (265 aa)
THSD1Thrombospondin type 1 domain containing 1. (787 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1346 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (838 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (747 aa)
ENSNLEP00000039968Nucleoplasmin domain-containing protein. (274 aa)
GIT2GIT ArfGAP 2. (760 aa)
GSNGelsolin. (814 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
FHL2Uncharacterized protein. (361 aa)
ENSNLEP00000041044CRIB domain-containing protein. (338 aa)
RHOBRas homolog family member B. (196 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (299 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (827 aa)
GIT1GIT ArfGAP 1. (772 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
ENSNLEP00000041829PIPK domain-containing protein. (329 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (825 aa)
ENSNLEP00000041962Calponin-homology (CH) domain-containing protein. (275 aa)
RSU1Ras suppressor protein 1. (277 aa)
RAC2Rac family small GTPase 2. (192 aa)
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
ENSNLEP00000042936Protein kinase domain-containing protein. (201 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
ENSNLEP00000043511Uncharacterized protein. (163 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
LOC10058324514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa)
FOCADFocadhesin. (1776 aa)
PIP5K1CPIPK domain-containing protein. (759 aa)
PPFIBP1PPFIA binding protein 1. (1011 aa)
EZREzrin. (586 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (328 aa)
PFN1-2Profilin; Belongs to the profilin family. (128 aa)
SYNPO2Synaptopodin 2. (1261 aa)
LOC100593698Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (172 aa)
PXNUncharacterized protein. (1078 aa)
ENSNLEP00000048155Uncharacterized protein. (265 aa)
SRCTyrosine-protein kinase. (537 aa)
ENAHWH1 domain-containing protein. (805 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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