STRINGSTRING
SYTL2 SYTL2 RPH3A RPH3A RASAL1 RASAL1 PLCH2 PLCH2 PRKCA PRKCA ITSN2 ITSN2 PLCL2 PLCL2 SYTL5 SYTL5 UNC13D UNC13D WWP1 WWP1 ESYT2 ESYT2 CPNE3 CPNE3 OTOF OTOF CPNE2 CPNE2 PLCB2 PLCB2 CPNE4 CPNE4 PLCH1 PLCH1 RIMS2 RIMS2 LOC100591987 LOC100591987 PLA2G4E PLA2G4E PLA2G4D PLA2G4D CPNE9 CPNE9 PLA2G4F PLA2G4F ESYT3 ESYT3 PIK3C2G PIK3C2G PLCZ1 PLCZ1 PLCB3 PLCB3 SYT1 SYT1 PLCD3 PLCD3 PLCD1 PLCD1 FER1L6 FER1L6 WWP2 WWP2 SYT3 SYT3 PRKCG PRKCG SYT12 SYT12 RIMS4 RIMS4 HECW2 HECW2 PRKCD PRKCD C2CD2L C2CD2L SYTL4 SYTL4 RASA3 RASA3 DOC2A DOC2A RASA4B RASA4B BAIAP3 BAIAP3 SYTL1 SYTL1 SYDE2 SYDE2 PKN2 PKN2 C2CD4D C2CD4D RAB11FIP5 RAB11FIP5 PLCG2 PLCG2 WWC2 WWC2 SYT4 SYT4 CPNE5 CPNE5 SYTL3 SYTL3 CADPS CADPS PRKCQ PRKCQ CEP120 CEP120 CADPS2 CADPS2 C2CD4A C2CD4A RIMS3 RIMS3 RAB11FIP1 RAB11FIP1 SYT11 SYT11 MCTP2 MCTP2 PLCE1 PLCE1 TOLLIP TOLLIP CC2D1A CC2D1A SYT8 SYT8 RASA1 RASA1 SYT16 SYT16 PLCB1 PLCB1 PIK3C2B PIK3C2B PLCB4 PLCB4 RPGRIP1 RPGRIP1 CCDC33 CCDC33 CAPN6 CAPN6 SMURF2 SMURF2 CPNE6 CPNE6 CPNE7 CPNE7 CC2D2A CC2D2A SYT10 SYT10 RGS3 RGS3 PRKCE PRKCE C2CD3 C2CD3 TC2N TC2N SYT9 SYT9 ESYT1 ESYT1 PIK3C2A PIK3C2A SYT13 SYT13 CC2D1B CC2D1B PLA2G4A PLA2G4A WWC3 WWC3 RASA2 RASA2 WWC1 WWC1 SYNGAP1 SYNGAP1 INPP4B INPP4B PKN1 PKN1 RAB11FIP2 RAB11FIP2 ENSNLEP00000026359 ENSNLEP00000026359 LOC100581641 LOC100581641 ABR ABR RASAL2 RASAL2 C2CD5 C2CD5 PLCL1 PLCL1 PRKCH PRKCH UVRAG UVRAG HECW1 HECW1 SYT6 SYT6 CAPN5 CAPN5 MCTP1 MCTP1 DYSF DYSF MYOF MYOF FER1L4 FER1L4 ENSNLEP00000037075 ENSNLEP00000037075 RPGRIP1L RPGRIP1L INPP4A INPP4A UNC13C UNC13C SYT7 SYT7 SYT15 SYT15 UNC13B UNC13B RIMS1 RIMS1 ENSNLEP00000042279 ENSNLEP00000042279 C2CD2 C2CD2 SYT5 SYT5 PLCD4 PLCD4 PRKCB PRKCB SYT14 SYT14 LOC100582927 LOC100582927 DAB2IP DAB2IP ITCH ITCH SYT17 SYT17 UNC13A UNC13A LOC100596652 LOC100596652 FER1L5 FER1L5 BCR BCR LOC100583249 LOC100583249 SYT2 SYT2 CPNE8 CPNE8 SMURF1 SMURF1 ENSNLEP00000048238 ENSNLEP00000048238 ITSN1 ITSN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYTL2Uncharacterized protein. (2220 aa)
RPH3ARabphilin 3A. (693 aa)
RASAL1RAS protein activator like 1. (776 aa)
PLCH2Phosphoinositide phospholipase C. (1360 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
ITSN2Intersectin 2. (1643 aa)
PLCL2Phosphoinositide phospholipase C. (1120 aa)
SYTL5Synaptotagmin like 5. (752 aa)
UNC13DUnc-13 homolog D. (1082 aa)
WWP1E3 ubiquitin-protein ligase. (922 aa)
ESYT2Extended synaptotagmin 2. (828 aa)
CPNE3Copine 3. (537 aa)
OTOFOtoferlin. (1968 aa)
CPNE2Copine 2. (540 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1083 aa)
CPNE4Copine 4. (575 aa)
PLCH1Phosphoinositide phospholipase C. (1693 aa)
RIMS2Uncharacterized protein. (1367 aa)
LOC100591987Phospholipase A2. (760 aa)
PLA2G4EPhospholipase A2. (867 aa)
PLA2G4DPhospholipase A2. (818 aa)
CPNE9Copine family member 9. (547 aa)
PLA2G4FPhospholipase A2. (850 aa)
ESYT3Extended synaptotagmin 3. (878 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1486 aa)
PLCZ1Phosphoinositide phospholipase C. (608 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
SYT1Synaptotagmin 1. (422 aa)
PLCD3Phosphoinositide phospholipase C. (770 aa)
PLCD1Phosphoinositide phospholipase C. (779 aa)
FER1L6Fer-1 like family member 6. (1857 aa)
WWP2E3 ubiquitin-protein ligase. (821 aa)
SYT3Synaptotagmin 3. (584 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
SYT12Synaptotagmin 12. (421 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (216 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
C2CD2LC2CD2 like. (716 aa)
SYTL4Synaptotagmin like 4. (672 aa)
RASA3RAS p21 protein activator 3. (816 aa)
DOC2ADouble C2 domain alpha. (355 aa)
RASA4BRas-GAP domain-containing protein. (727 aa)
BAIAP3BAI1 associated protein 3. (1094 aa)
SYTL1Synaptotagmin like 1. (561 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1194 aa)
PKN2Uncharacterized protein. (984 aa)
C2CD4DC2 calcium dependent domain containing 4D. (353 aa)
RAB11FIP5RAB11 family interacting protein 5. (645 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
WWC2WW and C2 domain containing 2. (1155 aa)
SYT4Synaptotagmin 4. (425 aa)
CPNE5Copine 5. (579 aa)
SYTL3Synaptotagmin like 3. (609 aa)
CADPSUncharacterized protein. (1183 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
CEP120Centrosomal protein 120. (987 aa)
CADPS2Calcium dependent secretion activator 2. (1297 aa)
C2CD4AC2 calcium dependent domain containing 4A. (347 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
RAB11FIP1RAB11 family interacting protein 1. (1221 aa)
SYT11Synaptotagmin 11. (431 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (889 aa)
PLCE1Phosphoinositide phospholipase C. (2303 aa)
TOLLIPToll interacting protein. (274 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (902 aa)
SYT8Synaptotagmin 8. (400 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
SYT16Synaptotagmin 16. (645 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1565 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
RPGRIP1RPGR interacting protein 1. (1282 aa)
CCDC33Coiled-coil domain containing 33. (718 aa)
CAPN6Calpain 6; Belongs to the peptidase C2 family. (641 aa)
SMURF2E3 ubiquitin-protein ligase. (745 aa)
CPNE6Copine 6. (607 aa)
CPNE7Copine 7. (560 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1620 aa)
SYT10Synaptotagmin 10. (523 aa)
RGS3Regulator of G protein signaling 3. (1186 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2317 aa)
TC2NTandem C2 domains, nuclear. (490 aa)
SYT9Synaptotagmin 9. (472 aa)
ESYT1Extended synaptotagmin 1. (1073 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
SYT13Synaptotagmin 13. (426 aa)
CC2D1BCoiled-coil and C2 domain containing 1B. (772 aa)
PLA2G4APhospholipase A2. (749 aa)
WWC3WWC family member 3. (1231 aa)
RASA2RAS p21 protein activator 2. (849 aa)
WWC1WW and C2 domain containing 1. (1040 aa)
SYNGAP1Ras-GAP domain-containing protein. (1226 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (938 aa)
PKN1Protein kinase domain-containing protein. (839 aa)
RAB11FIP2RAB11 family interacting protein 2. (532 aa)
ENSNLEP00000026359C2 domain-containing protein. (356 aa)
LOC100581641Uncharacterized protein. (352 aa)
ABRABR activator of RhoGEF and GTPase. (847 aa)
RASAL2RAS protein activator like 2. (1280 aa)
C2CD5C2 calcium dependent domain containing 5. (1042 aa)
PLCL1Phosphoinositide phospholipase C. (1095 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
UVRAGUV radiation resistance associated. (699 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1613 aa)
SYT6Uncharacterized protein. (480 aa)
CAPN5Calpain 5; Belongs to the peptidase C2 family. (679 aa)
MCTP1Uncharacterized protein. (808 aa)
DYSFDysferlin. (2085 aa)
MYOFMyoferlin. (2061 aa)
FER1L4Uncharacterized protein. (1900 aa)
ENSNLEP00000037075Uncharacterized protein. (572 aa)
RPGRIP1LRPGRIP1 like. (1269 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (972 aa)
UNC13CC2 domain-containing protein. (135 aa)
SYT7Uncharacterized protein. (592 aa)
SYT15Uncharacterized protein. (474 aa)
UNC13BUncharacterized protein. (4218 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1637 aa)
ENSNLEP00000042279Uncharacterized protein. (587 aa)
C2CD2C2 calcium dependent domain containing 2. (697 aa)
SYT5C2 domain-containing protein. (235 aa)
PLCD4Phosphoinositide phospholipase C. (743 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
SYT14C2 domain-containing protein. (864 aa)
LOC100582927Protein kinase domain-containing protein. (934 aa)
DAB2IPDAB2 interacting protein. (1159 aa)
ITCHE3 ubiquitin-protein ligase. (905 aa)
SYT17Synaptotagmin 17. (474 aa)
UNC13AUnc-13 homolog A. (1460 aa)
LOC100596652Uncharacterized protein. (295 aa)
FER1L5Fer-1 like family member 5. (2018 aa)
BCRBCR activator of RhoGEF and GTPase. (1271 aa)
LOC100583249E3 ubiquitin-protein ligase. (807 aa)
SYT2Synaptotagmin 2. (419 aa)
CPNE8Copine 8. (564 aa)
SMURF1E3 ubiquitin-protein ligase. (749 aa)
ENSNLEP00000048238Uncharacterized protein. (499 aa)
ITSN1Intersectin 1. (1675 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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