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THAP7 THAP7 ITPR3 ITPR3 PPP2CA PPP2CA GNAI3 GNAI3 CAMKK2 CAMKK2 PRKAR1A PRKAR1A CAMK2A CAMK2A GNAL GNAL ENSNLEP00000043756 ENSNLEP00000043756 OPRM1 OPRM1 CAMKK1 CAMKK1 PDE4C PDE4C PDE1C PDE1C ENSNLEP00000046477 ENSNLEP00000046477 ADCY1 ADCY1 GNA15 GNA15 ENSNLEP00000047903 ENSNLEP00000047903 ADCY5 ADCY5 THAP6 THAP6 CAMK2D CAMK2D GNG7 GNG7 GNG12 GNG12 ADCY8 ADCY8 PRKACG PRKACG ENSNLEP00000036861 ENSNLEP00000036861 PPP2R1A PPP2R1A PDE1A PDE1A PDE4A PDE4A ITPR2 ITPR2 ADCY9 ADCY9 PRKAR2B PRKAR2B PPP2R1B PPP2R1B LOC100592070 LOC100592070 PPP3CA PPP3CA PRKAR2A PRKAR2A GNB5 GNB5 GNG2 GNG2 ADCY6 ADCY6 DCLK1 DCLK1 GNB3 GNB3 PRKACB PRKACB ENSNLEP00000028868 ENSNLEP00000028868 LOC100586578 LOC100586578 PDE4D PDE4D PDE4B PDE4B MAPK1 MAPK1 PPP3CB PPP3CB PPP3R1 PPP3R1 GNG4 GNG4 GNG13 GNG13 PRKACA PRKACA LRBA LRBA PLA2G4A PLA2G4A PDE1B PDE1B CAMK2G CAMK2G PPP3CC PPP3CC ADCY4 ADCY4 GNG11 GNG11 GNGT1 GNGT1 G1RZK2_NOMLE G1RZK2_NOMLE GNAT3 GNAT3 PLCB4 PLCB4 PLCB1 PLCB1 PPP2CB PPP2CB GNB2 GNB2 ADCY2 ADCY2 CAMK4 CAMK4 CNBD2 CNBD2 GNG5 GNG5 GNAI1 GNAI1 PDYN PDYN PRKX PRKX PRKAR1B PRKAR1B PRKCD PRKCD CREB1 CREB1 GNAI2 GNAI2 PPP1CA PPP1CA GRK2 GRK2 PRKCG PRKCG GNB4 GNB4 PLCB3 PLCB3 PPP2R5D PPP2R5D G1QVV4_NOMLE G1QVV4_NOMLE CDK5 CDK5 GNG3 GNG3 CAMK2B CAMK2B ITPR1 ITPR1 AHCYL1 AHCYL1 GNGT2 GNGT2 GNAQ GNAQ GNA14 GNA14 PLCB2 PLCB2 GNG8 GNG8 GNA11 GNA11 KPNA2 KPNA2 NBEA NBEA POMC POMC ADCY3 ADCY3 PTRHD1 PTRHD1 PPP1R1B PPP1R1B ADCY7 ADCY7 PRKCA PRKCA GNB1 GNB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THAP7THAP domain containing 7. (304 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2755 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (591 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
GNALG protein subunit alpha L. (452 aa)
ENSNLEP00000043756Importin subunit alpha; Functions in nuclear protein import. (474 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (505 aa)
PDE4CPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (624 aa)
PDE1CPhosphodiesterase. (766 aa)
ENSNLEP00000046477Uncharacterized protein. (273 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
GNA15G protein subunit alpha 15. (322 aa)
ENSNLEP00000047903Uncharacterized protein. (340 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
THAP6THAP domain containing 6. (222 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
PRKACGUncharacterized protein. (290 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (588 aa)
PDE1APhosphodiesterase. (544 aa)
PDE4APhosphodiesterase. (869 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1310 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (343 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (666 aa)
LOC100592070Uncharacterized protein; Belongs to the protein kinase superfamily. (347 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
GNB5G protein subunit beta 5. (357 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
GNB3G protein subunit beta 3. (335 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSNLEP00000028868G protein gamma domain-containing protein. (64 aa)
LOC100586578Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PDE4DPhosphodiesterase. (748 aa)
PDE4BPhosphodiesterase. (736 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
PPP3CBSerine/threonine-protein phosphatase. (408 aa)
PPP3R1Uncharacterized protein. (189 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (116 aa)
GNG13G protein subunit gamma 13. (67 aa)
PRKACAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
LRBALPS responsive beige-like anchor protein. (2816 aa)
PLA2G4APhospholipase A2. (749 aa)
PDE1BPhosphodiesterase. (536 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (524 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1026 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
G1RZK2_NOMLECyclic nucleotide-binding domain-containing protein. (82 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
GNB2G protein subunit beta 2. (325 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (511 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAI1G protein subunit alpha i1. (353 aa)
PDYNProdynorphin. (254 aa)
PRKXProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (318 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (320 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (589 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNB4G protein subunit beta 4. (340 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (607 aa)
G1QVV4_NOMLEGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (292 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (607 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (529 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
GNAQG protein subunit alpha q. (358 aa)
GNA14G protein subunit alpha 14. (355 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1083 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNA11Uncharacterized protein. (217 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (499 aa)
NBEANeurobeachin. (2946 aa)
POMCProopiomelanocortin. (243 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (983 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
GNB1G protein subunit beta 1. (340 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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