STRINGSTRING
MEMO1 MEMO1 EGF EGF PRKCE PRKCE ERAS ERAS RPS27A-2 RPS27A-2 AKT3 AKT3 HSP90AA1 HSP90AA1 AKT1 AKT1 PTK6 PTK6 PIK3R1 PIK3R1 ENSNLEP00000034619 ENSNLEP00000034619 ENSNLEP00000035121 ENSNLEP00000035121 EGFR EGFR ENSNLEP00000036737 ENSNLEP00000036737 ENSNLEP00000037583 ENSNLEP00000037583 CSDE1 CSDE1 ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038869 ENSNLEP00000038869 FNDC3A FNDC3A ENSNLEP00000039370 ENSNLEP00000039370 NRAS NRAS GRB2 GRB2 CUL5 CUL5 FYN FYN AKT2 AKT2 PTPN12 PTPN12 NRG4 NRG4 RPS27A RPS27A NRG1 NRG1 ENSNLEP00000046563 ENSNLEP00000046563 MATK MATK NRG3 NRG3 ERBB3 ERBB3 SRC SRC ERBB2 ERBB2 DIAPH1 DIAPH1 PRKCA PRKCA GRB7 GRB7 ERBIN ERBIN G1QVX5_NOMLE G1QVX5_NOMLE KRAS KRAS GAB1 GAB1 FNDC3B FNDC3B PIK3CA PIK3CA USP8 USP8 PLCG1 PLCG1 RHOA RHOA YES1 YES1 ERBB4 ERBB4 PRKCD PRKCD EREG EREG BTC BTC STUB1 STUB1 HRAS HRAS NRG2 NRG2 HBEGF HBEGF PTPN18 PTPN18 RNF41 RNF41 SHC1 SHC1 CDC37 CDC37 SOS1 SOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEMO1Uncharacterized protein. (297 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
ERASES cell expressed Ras. (233 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (853 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
PTK6Tyrosine-protein kinase. (451 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
ENSNLEP00000035121Uncharacterized protein. (272 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
FYNTyrosine-protein kinase. (537 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (755 aa)
NRG4Neuregulin 4. (117 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
NRG1Neuregulin 1. (713 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
MATKTyrosine-protein kinase. (549 aa)
NRG3Neuregulin 3. (720 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1343 aa)
SRCTyrosine-protein kinase. (537 aa)
ERBB2Receptor protein-tyrosine kinase. (1247 aa)
DIAPH1Diaphanous related formin 1. (1214 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
GRB7Growth factor receptor bound protein 7. (476 aa)
ERBINErbb2 interacting protein. (1418 aa)
G1QVX5_NOMLEUncharacterized protein. (361 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1117 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
RHOARas homolog family member A. (193 aa)
YES1Tyrosine-protein kinase. (519 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
EREGEpiregulin. (169 aa)
BTCBetacellulin. (178 aa)
STUB1Uncharacterized protein. (231 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
NRG2Uncharacterized protein. (597 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PTPN18Protein tyrosine phosphatase non-receptor type 18. (458 aa)
RNF41Ring finger protein 41. (317 aa)
SHC1SHC adaptor protein 1. (542 aa)
CDC37Cell division cycle 37. (355 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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