STRINGSTRING
NCOR1 NCOR1 PSEN2 PSEN2 GABRQ GABRQ ENSNLEP00000034619 ENSNLEP00000034619 ENSNLEP00000032543 ENSNLEP00000032543 PIK3R1 PIK3R1 YAP1 YAP1 DLG4 DLG4 PSEN1 PSEN1 ADAP1 ADAP1 WWP1 WWP1 M3ZBW0_NOMLE M3ZBW0_NOMLE G1QGY8_NOMLE G1QGY8_NOMLE RPS27A-2 RPS27A-2 ERAS ERAS GABRB1 GABRB1 EGF EGF SOS1 SOS1 SPARC SPARC ESR1 ESR1 EGFR EGFR APOE APOE GABRB2 GABRB2 KRAS KRAS FNDC3B FNDC3B PIK3CA PIK3CA ADAP2 ADAP2 NEDD4 NEDD4 PGR PGR ERBB4 ERBB4 CSN2 CSN2 EREG EREG BTC BTC HRAS HRAS NRG2 NRG2 HBEGF HBEGF APH1A APH1A GABRG3 GABRG3 SHC1 SHC1 APH1B APH1B WWOX WWOX TAB2 TAB2 ADAM17 ADAM17 NCSTN NCSTN SRC SRC GABRB3 GABRB3 ERBB3 ERBB3 STMN1 STMN1 NRG3 NRG3 LOC100583249 LOC100583249 ENSNLEP00000046563 ENSNLEP00000046563 NRG1 NRG1 GFAP GFAP ITCH ITCH RPS27A RPS27A NRG4 NRG4 GRB2 GRB2 NRAS NRAS GABRG2 GABRG2 ENSNLEP00000039370 ENSNLEP00000039370 CXCL12 CXCL12 FNDC3A FNDC3A ENSNLEP00000038869 ENSNLEP00000038869 ENSNLEP00000038579 ENSNLEP00000038579 CSDE1 CSDE1 GABRA1 GABRA1 ENSNLEP00000037583 ENSNLEP00000037583 PSENEN PSENEN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCOR1Nuclear receptor corepressor 1. (2442 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (631 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
ENSNLEP00000032543Uncharacterized protein. (168 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
YAP1Uncharacterized protein. (418 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (746 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ADAP1ArfGAP with dual PH domains 1. (357 aa)
WWP1E3 ubiquitin-protein ligase. (922 aa)
M3ZBW0_NOMLESH2 domain-containing protein. (230 aa)
G1QGY8_NOMLEUncharacterized protein. (134 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
ERASES cell expressed Ras. (233 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
APOEApolipoprotein E. (305 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
ADAP2ArfGAP with dual PH domains 2. (377 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
PGRUncharacterized protein. (339 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (226 aa)
EREGEpiregulin. (169 aa)
BTCBetacellulin. (178 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
NRG2Uncharacterized protein. (597 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
SHC1SHC adaptor protein 1. (542 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
WWOXWW domain containing oxidoreductase. (413 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
NCSTNNicastrin. (702 aa)
SRCTyrosine-protein kinase. (537 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1343 aa)
STMN1Stathmin; Belongs to the stathmin family. (172 aa)
NRG3Neuregulin 3. (720 aa)
LOC100583249E3 ubiquitin-protein ligase. (807 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
NRG1Neuregulin 1. (713 aa)
GFAPIF rod domain-containing protein; Belongs to the intermediate filament family. (517 aa)
ITCHE3 ubiquitin-protein ligase. (905 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
NRG4Neuregulin 4. (117 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
CSDE1Cold shock domain containing E1. (844 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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