STRINGSTRING
FNDC3B FNDC3B YES1 YES1 CBL CBL SH2B2 SH2B2 KIT KIT SOS1 SOS1 SOCS1 SOCS1 SOCS6 SOCS6 ENSNLEP00000028656 ENSNLEP00000028656 FNDC3A FNDC3A GRB2 GRB2 FYN FYN SRC SRC PRKCA PRKCA SH2B3 SH2B3 LYN LYN LCK LCK PTPN6 PTPN6 KITLG KITLG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
YES1Tyrosine-protein kinase. (519 aa)
CBLCbl proto-oncogene. (905 aa)
SH2B2Uncharacterized protein. (579 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
SOCS1Suppressor of cytokine signaling 1. (208 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
ENSNLEP00000028656Uncharacterized protein. (436 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FYNTyrosine-protein kinase. (537 aa)
SRCTyrosine-protein kinase. (537 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
SH2B3SH2B adaptor protein 3. (567 aa)
LYNTyrosine-protein kinase. (512 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (627 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (26%) [HD]