STRINGSTRING
MAPK12 MAPK12 NOD2 NOD2 RIPK2 RIPK2 MAP2K6 MAP2K6 CASP2 CASP2 IRAK2 IRAK2 NAIP NAIP UBE2N UBE2N BIRC3 BIRC3 CASP4 CASP4 CASP9 CASP9 CARD9 CARD9 MAPK13 MAPK13 BIRC7 BIRC7 IKBKB IKBKB MAP3K7 MAP3K7 IKBKG IKBKG TNFAIP3 TNFAIP3 NOD1 NOD1 TAB1 TAB1 TAB2 TAB2 TRAF6 TRAF6 RPS27A-2 RPS27A-2 MAPK14 MAPK14 MAP3K20 MAP3K20 MAPK11 MAPK11 CHUK CHUK ENSNLEP00000027432 ENSNLEP00000027432 CYLD CYLD ENSNLEP00000034619 ENSNLEP00000034619 AAMP AAMP ENSNLEP00000037583 ENSNLEP00000037583 BIRC2 BIRC2 ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038869 ENSNLEP00000038869 ENSNLEP00000039390 ENSNLEP00000039390 CASP8 CASP8 ENSNLEP00000041707 ENSNLEP00000041707 ENSNLEP00000042204 ENSNLEP00000042204 RPS27A RPS27A CASP1 CASP1 ITCH ITCH TAB3 TAB3 ENSNLEP00000049227 ENSNLEP00000049227
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK12Mitogen-activated protein kinase. (368 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (568 aa)
NAIPNLR family apoptosis inhibitory protein. (1257 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
BIRC3Baculoviral IAP repeat containing 3. (603 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (377 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (426 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
IKBKGNEMO domain-containing protein. (173 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
MAPK11Mitogen-activated protein kinase. (350 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
ENSNLEP00000027432TNF receptor-associated factor. (488 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
AAMPAngio associated migratory cell protein. (434 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
BIRC2Baculoviral IAP repeat containing 2. (615 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
ENSNLEP00000039390Protein kinase domain-containing protein. (673 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
ENSNLEP00000041707UBIQUITIN_CONJUGAT_2 domain-containing protein. (77 aa)
ENSNLEP00000042204UBIQUITIN_CONJUGAT_2 domain-containing protein. (131 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
ITCHE3 ubiquitin-protein ligase. (905 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
ENSNLEP00000049227Uncharacterized protein. (122 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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