87 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ENSNLEP00000029417	Uncharacterized protein. (200 aa)
	POLR2H	RNA polymerase II subunit H. (174 aa)
	ENSNLEP00000028102	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (638 aa)
	CCDC71L	Uncharacterized protein. (293 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
	ENSNLEP00000039422	Ubiquitin-like domain-containing protein. (136 aa)
	POLR2K	Uncharacterized protein. (77 aa)
	ENSNLEP00000039357	Ku domain-containing protein. (451 aa)
	ENSNLEP00000039234	Uncharacterized protein. (193 aa)
	ENSNLEP00000042001	TFIIS-type domain-containing protein. (91 aa)
	ENSNLEP00000042015	Uncharacterized protein. (723 aa)
	POLR3B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa)
	ENSNLEP00000038869	Ubiquitin-like domain-containing protein. (156 aa)
	ENSNLEP00000038579	Ubiquitin-like domain-containing protein. (104 aa)
	NKIRAS1	NFKB inhibitor interacting Ras like 1. (192 aa)
	ENSNLEP00000037583	Ubiquitin-like domain-containing protein. (79 aa)
	ENSNLEP00000037137	SAP domain-containing protein. (225 aa)
	ENSNLEP00000036685	Ku domain-containing protein. (329 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	DDX41	DEAD-box helicase 41. (585 aa)
	EP300	E1A binding protein p300. (2306 aa)
	TRIM32	Tripartite motif containing 32. (653 aa)
	POLR2F	Uncharacterized protein. (177 aa)
	ENSNLEP00000047217	Uncharacterized protein. (67 aa)
	LRRFIP1	Uncharacterized protein. (677 aa)
	LRRFIP2	LRR binding FLII interacting protein 2. (721 aa)
	RPS27A-2	Ubiquitin-like domain-containing protein. (156 aa)
	G1SA94_NOMLE	Uncharacterized protein. (55 aa)
	DHX9	DExH-box helicase 9. (1275 aa)
	STAT6	Signal transducer and activator of transcription. (842 aa)
	TRIM21	Tripartite motif containing 21. (475 aa)
	TBK1	TANK binding kinase 1. (729 aa)
	DHX57	DExH-box helicase 57. (1387 aa)
	XRCC6	X-ray repair cross complementing 6. (535 aa)
	POLR3H	RNA polymerase III subunit H. (204 aa)
	G1S012_NOMLE	Uncharacterized protein. (348 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (161 aa)
	RIPK3	Receptor interacting serine/threonine kinase 3. (506 aa)
	POLR3G	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
	LOC100580673	Ku domain-containing protein. (534 aa)
	TRIM56	Tripartite motif containing 56. (755 aa)
	NKIRAS2	NFKB inhibitor interacting Ras like 2. (231 aa)
	POLR1C	RNA polymerase I and III subunit C. (348 aa)
	NFKBIA	NFKB inhibitor alpha. (305 aa)
	DHX36	DEAH-box helicase 36. (1007 aa)
	DHX29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1369 aa)
	CRCP	CGRP receptor component. (148 aa)
	POLR2E	RNA polymerase II subunit E. (211 aa)
	MFSD1	Major facilitator superfamily domain containing 1. (513 aa)
	IRF3	IRF tryptophan pentad repeat domain-containing protein. (301 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
	POLR3C	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	POLR3GL	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (218 aa)
	KXD1	KxDL motif containing 1. (195 aa)
	ZBP1	Z-DNA binding protein 1. (429 aa)
	XRCC5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
	NFKB2	Nuclear factor kappa B subunit 2. (900 aa)
	TRIM58	Tripartite motif containing 58. (486 aa)
	POLR3K	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
	IRF7	Interferon regulatory factor 7. (524 aa)
	POLR2L	RNA polymerase II subunit L. (67 aa)
	G1RD82_NOMLE	Uncharacterized protein. (342 aa)
	YTHDC1	YTH domain containing 1. (725 aa)
	G1RWX7_NOMLE	ANK_REP_REGION domain-containing protein. (182 aa)
	IKBKG	NEMO domain-containing protein. (173 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (969 aa)
	TICAM1	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa)
	PRKDC	Protein kinase, DNA-activated, catalytic subunit. (3853 aa)
	G1RS08_NOMLE	Uncharacterized protein. (164 aa)
	AIM2	Absent in melanoma 2. (344 aa)
	IFI16	Interferon gamma inducible protein 16. (723 aa)
	DTX4	Deltex E3 ubiquitin ligase 4. (619 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
	POLR3E	RNA polymerase III subunit E. (679 aa)
	YTHDC2	YTH domain containing 2. (1430 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (671 aa)
	NLRP4	NLR family pyrin domain containing 4. (998 aa)
	POLR3A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1276 aa)
	POLR3F	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
	CREBBP	CREB binding protein. (2442 aa)
	NLRC3	NLR family CARD domain containing 3. (1102 aa)
	ENSNLEP00000034619	Ubiquitin-like domain-containing protein. (77 aa)
	ENSNLEP00000031956	Uncharacterized protein. (104 aa)
	DHX30	DExH-box helicase 30. (1124 aa)
	MRE11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIM2	DDX41	ENSNLEP00000015970	ENSNLEP00000036309	Absent in melanoma 2.	DEAD-box helicase 41.	0.510
AIM2	G1RD82_NOMLE	ENSNLEP00000015970	ENSNLEP00000011181	Absent in melanoma 2.	Uncharacterized protein.	0.521
AIM2	IFI16	ENSNLEP00000015970	ENSNLEP00000015957	Absent in melanoma 2.	Interferon gamma inducible protein 16.	0.973
AIM2	IRF3	ENSNLEP00000015970	ENSNLEP00000006381	Absent in melanoma 2.	IRF tryptophan pentad repeat domain-containing protein.	0.485
AIM2	IRF7	ENSNLEP00000015970	ENSNLEP00000010299	Absent in melanoma 2.	Interferon regulatory factor 7.	0.428
AIM2	MYD88	ENSNLEP00000015970	ENSNLEP00000006463	Absent in melanoma 2.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.469
AIM2	NLRP4	ENSNLEP00000015970	ENSNLEP00000013011	Absent in melanoma 2.	NLR family pyrin domain containing 4.	0.745
AIM2	TBK1	ENSNLEP00000015970	ENSNLEP00000020707	Absent in melanoma 2.	TANK binding kinase 1.	0.469
AIM2	TLR3	ENSNLEP00000015970	ENSNLEP00000013896	Absent in melanoma 2.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.517
AIM2	ZBP1	ENSNLEP00000015970	ENSNLEP00000008611	Absent in melanoma 2.	Z-DNA binding protein 1.	0.498
CHUK	CREBBP	ENSNLEP00000025468	ENSNLEP00000011912	Component of inhibitor of nuclear factor kappa B kinase complex.	CREB binding protein.	0.737
CHUK	CTNNB1	ENSNLEP00000025468	ENSNLEP00000006991	Component of inhibitor of nuclear factor kappa B kinase complex.	Catenin beta 1.	0.556
CHUK	ENSNLEP00000034619	ENSNLEP00000025468	ENSNLEP00000034619	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-like domain-containing protein.	0.618
CHUK	ENSNLEP00000037583	ENSNLEP00000025468	ENSNLEP00000037583	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-like domain-containing protein.	0.623
CHUK	ENSNLEP00000038579	ENSNLEP00000025468	ENSNLEP00000038579	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-like domain-containing protein.	0.623
CHUK	ENSNLEP00000038869	ENSNLEP00000025468	ENSNLEP00000038869	Component of inhibitor of nuclear factor kappa B kinase complex.	Ubiquitin-like domain-containing protein.	0.527
CHUK	EP300	ENSNLEP00000025468	ENSNLEP00000035934	Component of inhibitor of nuclear factor kappa B kinase complex.	E1A binding protein p300.	0.591
CHUK	G1RD82_NOMLE	ENSNLEP00000025468	ENSNLEP00000011181	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.782
CHUK	G1RWX7_NOMLE	ENSNLEP00000025468	ENSNLEP00000017754	Component of inhibitor of nuclear factor kappa B kinase complex.	ANK_REP_REGION domain-containing protein.	0.949
CHUK	IKBKB	ENSNLEP00000025468	ENSNLEP00000015614	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.999

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