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CREB1 | cAMP responsive element binding protein 1. (341 aa) | ||||
MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) | ||||
PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (950 aa) | ||||
ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa) | ||||
AP2M1 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa) | ||||
SHC4 | SHC adaptor protein 4. (604 aa) | ||||
FOSL1 | BZIP domain-containing protein. (271 aa) | ||||
PIK3R2 | Uncharacterized protein. (727 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) | ||||
DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) | ||||
TRIB1 | Tribbles pseudokinase 1. (321 aa) | ||||
AP2A1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (906 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (607 aa) | ||||
CHD4 | Uncharacterized protein. (1987 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) | ||||
SRF | Serum response factor. (508 aa) | ||||
RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) | ||||
CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa) | ||||
RAP1A | RAP1A, member of RAS oncogene family. (184 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
ELK1 | ETS transcription factor ELK1. (390 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (383 aa) | ||||
RALA | RAS like proto-oncogene A. (206 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (764 aa) | ||||
G1QNP0_NOMLE | Protein kinase domain-containing protein. (234 aa) | ||||
FOSB | FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (278 aa) | ||||
RALB | RAS like proto-oncogene B. (212 aa) | ||||
CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa) | ||||
MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa) | ||||
CRK | Uncharacterized protein. (252 aa) | ||||
SHC2 | Uncharacterized protein. (516 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (368 aa) | ||||
CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) | ||||
VRK3 | VRK serine/threonine kinase 3. (474 aa) | ||||
AP2B1 | AP complex subunit beta. (951 aa) | ||||
CREM | cAMP responsive element modulator. (344 aa) | ||||
DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (770 aa) | ||||
ENSNLEP00000029200 | C2H2-type domain-containing protein. (398 aa) | ||||
NGF | NGF domain-containing protein; Belongs to the NGF-beta family. (123 aa) | ||||
ENSNLEP00000030293 | Uncharacterized protein. (912 aa) | ||||
ENSNLEP00000031226 | AP complex subunit beta. (907 aa) | ||||
ADCYAP1R1 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (500 aa) | ||||
TCF12 | Transcription factor 12. (706 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (716 aa) | ||||
PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (666 aa) | ||||
ENSNLEP00000036737 | Uncharacterized protein. (160 aa) | ||||
ENSNLEP00000036861 | Uncharacterized protein. (119 aa) | ||||
ENSNLEP00000032399 | Uncharacterized protein. (628 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (327 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1242 aa) | ||||
SHC3 | SHC adaptor protein 3. (598 aa) | ||||
EP300 | E1A binding protein p300. (2306 aa) | ||||
CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
ENSNLEP00000036455 | Uncharacterized protein. (127 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (522 aa) | ||||
PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (588 aa) | ||||
MEF2D | MADS-box domain-containing protein. (139 aa) | ||||
KIDINS220 | Kinase D interacting substrate 220. (1733 aa) | ||||
NKPD1 | NTPase KAP family P-loop domain containing 1. (608 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
DNM1 | Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (827 aa) | ||||
RIT2 | Ras like without CAAX 2. (217 aa) | ||||
ENSNLEP00000039370 | SH2 domain-containing protein. (299 aa) | ||||
FNBP4 | Formin binding protein 4. (1022 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
PPP2CA | Serine/threonine-protein phosphatase. (309 aa) | ||||
ENSNLEP00000042687 | Uncharacterized protein. (245 aa) | ||||
ENSNLEP00000042936 | Protein kinase domain-containing protein. (201 aa) | ||||
ASCL2 | Achaete-scute family bHLH transcription factor 2. (193 aa) | ||||
DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) | ||||
EGR2 | Early growth response 2. (476 aa) | ||||
IRS2 | Insulin receptor substrate 2. (1344 aa) | ||||
ENSNLEP00000046563 | Uncharacterized protein. (498 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (787 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (352 aa) | ||||
SRC | Tyrosine-protein kinase. (537 aa) | ||||
DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa) | ||||
NAB1 | NGFI-A binding protein 1. (487 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (350 aa) | ||||
ID3 | Inhibitor of DNA binding 3, HLH protein. (119 aa) | ||||
ATF1 | Activating transcription factor 1. (270 aa) | ||||
TPH1 | Tryptophan hydroxylase 1. (444 aa) | ||||
NAB2 | NGFI-A binding protein 2. (525 aa) | ||||
PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (855 aa) | ||||
DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) | ||||
EGR3 | Early growth response 3. (387 aa) | ||||
ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) | ||||
DNM3 | Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa) | ||||
DNAL4 | Dynein light chain. (105 aa) | ||||
SGK1 | Non-specific serine/threonine protein kinase. (526 aa) | ||||
TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
ID2 | Inhibitor of DNA binding 2. (134 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (414 aa) | ||||
RALGDS | Uncharacterized protein. (916 aa) | ||||
LYL1 | LYL1 basic helix-loop-helix family member. (280 aa) | ||||
RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1110 aa) | ||||
RIT1 | Ras like without CAAX 1. (236 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (309 aa) | ||||
RPS6KA2 | Non-specific serine/threonine protein kinase. (692 aa) | ||||
SHC1 | SHC adaptor protein 1. (542 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa) | ||||
SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3. (355 aa) | ||||
RPS6KA3 | Ribosomal protein S6 kinase. (732 aa) | ||||
ID1 | Inhibitor of DNA binding 1, HLH protein. (155 aa) | ||||
RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) | ||||
MEF2A | Myocyte enhancer factor 2A. (509 aa) | ||||
AP2S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (321 aa) | ||||
CDK5R2 | Cyclin-dependent kinase 5 activator. (367 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
ASCL1 | Achaete-scute family bHLH transcription factor 1. (235 aa) | ||||
RPS6KA5 | Ribosomal protein S6 kinase. (797 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) | ||||
REST | RE1 silencing transcription factor. (1097 aa) | ||||
AP2A2 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (923 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) | ||||
RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1219 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) |