STRINGSTRING
FRS2 FRS2 KIDINS220 KIDINS220 NKPD1 NKPD1 SHC3 SHC3 CSDE1 CSDE1 NRAS NRAS RIT2 RIT2 ENSNLEP00000039370 ENSNLEP00000039370 MAP2K1 MAP2K1 ENSNLEP00000036455 ENSNLEP00000036455 GRB2 GRB2 ENSNLEP00000042936 ENSNLEP00000042936 ENSNLEP00000046563 ENSNLEP00000046563 NTRK1 NTRK1 SRC SRC NGF NGF MAPK1 MAPK1 MAPK11 MAPK11 MAPK14 MAPK14 ERAS ERAS SOS1 SOS1 RALGDS RALGDS RAPGEF1 RAPGEF1 RIT1 RIT1 SHC1 SHC1 MAPK13 MAPK13 HRAS HRAS MAPKAPK3 MAPKAPK3 YWHAB YWHAB SHC4 SHC4 KRAS KRAS RAP1A RAP1A MAP2K2 MAP2K2 RALA RALA BRAF BRAF MAPK3 MAPK3 RALB RALB MAPKAPK2 MAPKAPK2 CRK CRK SHC2 SHC2 MAPK12 MAPK12 CRKL CRKL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
KIDINS220Kinase D interacting substrate 220. (1733 aa)
NKPD1NTPase KAP family P-loop domain containing 1. (608 aa)
SHC3SHC adaptor protein 3. (598 aa)
CSDE1Cold shock domain containing E1. (844 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RIT2Ras like without CAAX 2. (217 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSNLEP00000036455Uncharacterized protein. (127 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSNLEP00000042936Protein kinase domain-containing protein. (201 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
NTRK1Tyrosine-protein kinase receptor. (787 aa)
SRCTyrosine-protein kinase. (537 aa)
NGFNGF domain-containing protein; Belongs to the NGF-beta family. (123 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
MAPK11Mitogen-activated protein kinase. (350 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
ERASES cell expressed Ras. (233 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
RALGDSUncharacterized protein. (916 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1110 aa)
RIT1Ras like without CAAX 1. (236 aa)
SHC1SHC adaptor protein 1. (542 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
SHC4SHC adaptor protein 4. (604 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (383 aa)
RALARAS like proto-oncogene A. (206 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
RALBRAS like proto-oncogene B. (212 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa)
CRKUncharacterized protein. (252 aa)
SHC2Uncharacterized protein. (516 aa)
MAPK12Mitogen-activated protein kinase. (368 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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