STRINGSTRING
LOC100588715 LOC100588715 G1R458_NOMLE G1R458_NOMLE CYP19A1 CYP19A1 HSD3B1 HSD3B1 TSPO2 TSPO2 ENSNLEP00000034358 ENSNLEP00000034358 HSD11B1 HSD11B1 POMC POMC HSD17B2 HSD17B2 FADS6 FADS6 HSDL1 HSDL1 FDXR FDXR DHRS7C DHRS7C RIMBP2 RIMBP2 ENSNLEP00000035773 ENSNLEP00000035773 STARD3NL STARD3NL ENSNLEP00000038807 ENSNLEP00000038807 LOC100606563 LOC100606563 HSD11B2 HSD11B2 CYP11B2 CYP11B2 ENSNLEP00000043248 ENSNLEP00000043248 LOC105740713 LOC105740713 TSPOAP1 TSPOAP1 ENSNLEP00000047861 ENSNLEP00000047861 ENSNLEP00000048186 ENSNLEP00000048186 FDX1 FDX1 SRD5A3 SRD5A3 HSD17B12 HSD17B12 ENSNLEP00000030218 ENSNLEP00000030218 STARD3 STARD3 HSD17B11 HSD17B11 LHB LHB HSD17B3 HSD17B3 HSD3B2 HSD3B2 ENSNLEP00000026488 ENSNLEP00000026488 ENSNLEP00000026090 ENSNLEP00000026090 STARD4-2 STARD4-2 LOC100596087 LOC100596087 ENSNLEP00000024712 ENSNLEP00000024712 SERPINA6 SERPINA6 TSPO TSPO SRD5A2 SRD5A2 CYP17A1 CYP17A1 AKR1B1 AKR1B1 STAR STAR FDX2 FDX2 STARD6 STARD6 HSD17B1 HSD17B1 STARD4 STARD4 SRD5A1 SRD5A1 AKR1E2 AKR1E2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100588715Uncharacterized protein. (1638 aa)
G1R458_NOMLEUncharacterized protein; Belongs to the cytochrome P450 family. (135 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
HSD3B1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (373 aa)
TSPO2Translocator protein 2. (170 aa)
ENSNLEP00000034358Uncharacterized protein. (268 aa)
HSD11B1Hydroxysteroid 11-beta dehydrogenase 1. (291 aa)
POMCProopiomelanocortin. (243 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
FADS6Uncharacterized protein. (291 aa)
HSDL1Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
FDXRNADPH:adrenodoxin oxidoreductase, mitochondrial. (532 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
RIMBP2RIMS binding protein 2. (901 aa)
ENSNLEP00000035773Aldo_ket_red domain-containing protein. (273 aa)
STARD3NLSTARD3 N-terminal like. (234 aa)
ENSNLEP00000038807Uncharacterized protein. (1552 aa)
LOC1006065633Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (346 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (445 aa)
CYP11B2Cytochrome P450 family 11 subfamily B member 2; Belongs to the cytochrome P450 family. (566 aa)
ENSNLEP00000043248Uncharacterized protein. (285 aa)
LOC1057407132Fe-2S ferredoxin-type domain-containing protein. (172 aa)
TSPOAP1Uncharacterized protein. (757 aa)
ENSNLEP00000047861annotation not available (282 aa)
ENSNLEP00000048186Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (466 aa)
FDX1Ferredoxin 1. (184 aa)
SRD5A3Steroid 5 alpha-reductase 3. (318 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa)
ENSNLEP00000030218Uncharacterized protein. (112 aa)
STARD3Uncharacterized protein. (399 aa)
HSD17B11Hydroxysteroid 17-beta dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
LHBCys_knot domain-containing protein. (116 aa)
HSD17B3Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
HSD3B2Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family. (372 aa)
ENSNLEP00000026488Aldo_ket_red domain-containing protein. (282 aa)
ENSNLEP000000260903-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (258 aa)
STARD4-2Uncharacterized protein. (51 aa)
LOC1005960873Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (386 aa)
ENSNLEP000000247123Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (371 aa)
SERPINA6Serpin family A member 6; Belongs to the serpin family. (405 aa)
TSPOTranslocator protein. (169 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
FDX22Fe-2S ferredoxin-type domain-containing protein. (186 aa)
STARD6StAR related lipid transfer domain containing 6. (220 aa)
HSD17B1Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (328 aa)
STARD4START domain-containing protein. (199 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
AKR1E2Aldo-keto reductase family 1 member E2. (320 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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