STRINGSTRING
ERAS ERAS EGF EGF SOS1 SOS1 NRG2 NRG2 HBEGF HBEGF HRAS HRAS ERBB2 ERBB2 BTC BTC EREG EREG CSDE1 CSDE1 NRAS NRAS ERBB4 ERBB4 GRB2 GRB2 NRG3 NRG3 NRG1 NRG1 NRG4 NRG4 KRAS KRAS EGFR EGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERASES cell expressed Ras. (233 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
NRG2Uncharacterized protein. (597 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ERBB2Receptor protein-tyrosine kinase. (1247 aa)
BTCBetacellulin. (178 aa)
EREGEpiregulin. (169 aa)
CSDE1Cold shock domain containing E1. (844 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
NRG3Neuregulin 3. (720 aa)
NRG1Neuregulin 1. (713 aa)
NRG4Neuregulin 4. (117 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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