STRINGSTRING
SOX12 SOX12 SOX15 SOX15 XPO1 XPO1 CREBBP CREBBP PSMD4 PSMD4 PSMB4 PSMB4 HMGXB3 HMGXB3 SOX18 SOX18 TERT TERT PYGO2 PYGO2 APC APC RSPO1 RSPO1 PSMB5 PSMB5 ENSNLEP00000040983 ENSNLEP00000040983 ENSNLEP00000040898 ENSNLEP00000040898 LOC100583243 LOC100583243 ENSNLEP00000040208 ENSNLEP00000040208 H2BC5 H2BC5 H2BC7 H2BC7 ENSNLEP00000041226 ENSNLEP00000041226 RNF146 RNF146 RSPO3 RSPO3 WNT9A WNT9A LOC100599068 LOC100599068 PPP2CA PPP2CA PSMD1 PSMD1 ENSNLEP00000041604 ENSNLEP00000041604 BCL9 BCL9 LOC100587665 LOC100587665 AKT2 AKT2 LOC100591180 LOC100591180 CSNK1G3 CSNK1G3 DVL1 DVL1 ENSNLEP00000042742 ENSNLEP00000042742 H2AZ1 H2AZ1 ENSNLEP00000043021 ENSNLEP00000043021 H2AC6 H2AC6 H2BC3 H2BC3 ENSNLEP00000043421 ENSNLEP00000043421 DVL2 DVL2 PSMD2 PSMD2 PSMB2 PSMB2 ENSNLEP00000044037 ENSNLEP00000044037 FZD2 FZD2 RPS27A RPS27A PSME4 PSME4 ENSNLEP00000044711 ENSNLEP00000044711 ENSNLEP00000044724 ENSNLEP00000044724 USP34 USP34 CSNK1A1 CSNK1A1 ENSNLEP00000044921 ENSNLEP00000044921 ENSNLEP00000044923 ENSNLEP00000044923 ENSNLEP00000045034 ENSNLEP00000045034 PSMD6 PSMD6 ENSNLEP00000045113 ENSNLEP00000045113 H2BC13 H2BC13 LGR5 LGR5 ENSNLEP00000046239 ENSNLEP00000046239 PSMB7 PSMB7 RUNX3 RUNX3 ENSNLEP00000046925 ENSNLEP00000046925 PSMD13 PSMD13 ENSNLEP00000047148 ENSNLEP00000047148 CUL3 CUL3 FZD5 FZD5 TCF7 TCF7 BIRC8 BIRC8 ENSNLEP00000047555 ENSNLEP00000047555 ENSNLEP00000047693 ENSNLEP00000047693 LOC100593825 LOC100593825 ENSNLEP00000048056 ENSNLEP00000048056 DACT3 DACT3 ENSNLEP00000048393 ENSNLEP00000048393 AXIN1 AXIN1 RSPO2 RSPO2 ENSNLEP00000049149 ENSNLEP00000049149 ENSNLEP00000049245 ENSNLEP00000049245 ENSNLEP00000049320 ENSNLEP00000049320 DKK2 DKK2 H3C13 H3C13 PSME3 PSME3 ENSNLEP00000039561 ENSNLEP00000039561 ENSNLEP00000039422 ENSNLEP00000039422 TNKS TNKS ENSNLEP00000039192 ENSNLEP00000039192 ENSNLEP00000039191 ENSNLEP00000039191 ENSNLEP00000039177 ENSNLEP00000039177 ENSNLEP00000039157 ENSNLEP00000039157 ENSNLEP00000039110 ENSNLEP00000039110 ENSNLEP00000038869 ENSNLEP00000038869 H2AX H2AX ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038401 ENSNLEP00000038401 ENSNLEP00000038319 ENSNLEP00000038319 ENSNLEP00000037880 ENSNLEP00000037880 ENSNLEP00000037583 ENSNLEP00000037583 ENSNLEP00000037453 ENSNLEP00000037453 TLE4 TLE4 H2BC11 H2BC11 KAT5 KAT5 PSMB6 PSMB6 WNT8A WNT8A PPP2CB PPP2CB DKK1 DKK1 SFRP1 SFRP1 PPP2R1A PPP2R1A PSMF1 PSMF1 PSME2 PSME2 RBX1 RBX1 EP300 EP300 ENSNLEP00000035926 ENSNLEP00000035926 PPP2R5A PPP2R5A FZD4 FZD4 H2BC14 H2BC14 CTBP1 CTBP1 LEF1 LEF1 ENSNLEP00000034625 ENSNLEP00000034625 ENSNLEP00000034619 ENSNLEP00000034619 LOC105740194 LOC105740194 RNF43 RNF43 TRRAP TRRAP LOC100595614 LOC100595614 PSMB3 PSMB3 SOX17 SOX17 PSMD9 PSMD9 TCF7L1 TCF7L1 PSMD3 PSMD3 APC2 APC2 SOX4 SOX4 BHMG1 BHMG1 TLE6 TLE6 ZNRF3 ZNRF3 KREMEN1 KREMEN1 PSMC6 PSMC6 BTBD18 BTBD18 DKK4 DKK4 HDAC1 HDAC1 WIF1 WIF1 H2BU1 H2BU1 H2BC15 H2BC15 PSMA2 PSMA2 TLE1 TLE1 CSNK2A2 CSNK2A2 LRP6 LRP6 RYK RYK FZD6 FZD6 H2AZ2 H2AZ2 SOX30 SOX30 PSMC5 PSMC5 G1QWQ9_NOMLE G1QWQ9_NOMLE PPP2R5D PPP2R5D WNT3 WNT3 PSMB10 PSMB10 SOX5 SOX5 MEN1 MEN1 PPP2R5B PPP2R5B MYC MYC SOST SOST CTNNB1 CTNNB1 TLE7 TLE7 SFRP2 SFRP2 PSMD11 PSMD11 KXD1 KXD1 CSNK2B CSNK2B USP8 USP8 LEO1 LEO1 LRP5 LRP5 PSMA8 PSMA8 PYGO1 PYGO1 PSMB8 PSMB8 PSMB9 PSMB9 LRTM1 LRTM1 WNT5A WNT5A BCL9L BCL9L ZBTB44 ZBTB44 PIP5K1B PIP5K1B ENSNLEP00000034023 ENSNLEP00000034023 LOC100593400 LOC100593400 ENSNLEP00000033669 ENSNLEP00000033669 PSMB1 PSMB1 PSMA3 PSMA3 CSNK1G2 CSNK1G2 CXXC4 CXXC4 DACT1 DACT1 PSMD7 PSMD7 H2BW1 H2BW1 HECW1 HECW1 H2AC7 H2AC7 SMARCA4 SMARCA4 PSME1 PSME1 PPP2R1B PPP2R1B CAV1 CAV1 PSMD14 PSMD14 ENSNLEP00000031906 ENSNLEP00000031906 HIST2H2BE HIST2H2BE TLE3 TLE3 PSMD10 PSMD10 ENSNLEP00000030887 ENSNLEP00000030887 LOC100592963 LOC100592963 ENSNLEP00000030555 ENSNLEP00000030555 ENSNLEP00000030482 ENSNLEP00000030482 ENSNLEP00000029825 ENSNLEP00000029825 LOC100593203 LOC100593203 ENSNLEP00000029616 ENSNLEP00000029616 ENSNLEP00000029611 ENSNLEP00000029611 H3-4 H3-4 LRP5L LRP5L ENSNLEP00000029165 ENSNLEP00000029165 PSMA4 PSMA4 YWHAZ YWHAZ ENSNLEP00000028499 ENSNLEP00000028499 PSMA6 PSMA6 PSMA5 PSMA5 ENSNLEP00000028201 ENSNLEP00000028201 AKT1 AKT1 PSMD12 PSMD12 AMER1 AMER1 LOC100600196 LOC100600196 ASH2L ASH2L SOX9 SOX9 LOC100591996 LOC100591996 HIST1H2BO HIST1H2BO ENSNLEP00000026915 ENSNLEP00000026915 ENSNLEP00000026679 ENSNLEP00000026679 ENSNLEP00000026622 ENSNLEP00000026622 WNT3A WNT3A GSK3B GSK3B ENSNLEP00000026115 ENSNLEP00000026115 HIST1H2BK HIST1H2BK PPP2R5C PPP2R5C ENSNLEP00000025948 ENSNLEP00000025948 SOX1 SOX1 LOC100597637 LOC100597637 ENSNLEP00000024590 ENSNLEP00000024590 PSMA1 PSMA1 DVL3 DVL3 TNKS2 TNKS2 FRAT2 FRAT2 SOX14 SOX14 SOX2 SOX2 RPS27A-2 RPS27A-2 SOX3 SOX3 H2BC1 H2BC1 CSNK1A1L CSNK1A1L LOC100596300 LOC100596300 H2AC20 H2AC20 KLHL12 KLHL12 LGR6 LGR6 CDC73 CDC73 WNT1 WNT1 LGR4 LGR4 SOX6 SOX6 G1S5F9_NOMLE G1S5F9_NOMLE G1S5F4_NOMLE G1S5F4_NOMLE PSMD5 PSMD5 PSMC1 PSMC1 PSMD8 PSMD8 TCF7L2 TCF7L2 PSMA7 PSMA7 CBY1 CBY1 LOC100607246 LOC100607246 XIAP XIAP SMURF2 SMURF2 BTRC BTRC AXIN2 AXIN2 WNT8B WNT8B PSMC3 PSMC3 SLC39A13 SLC39A13 CHD8 CHD8 RBBP5 RBBP5 G1RVW8_NOMLE G1RVW8_NOMLE RUVBL1 RUVBL1 PSMC4 PSMC4 SOX13 SOX13 HMGXB4 HMGXB4 SOX8 SOX8 PSMC2 PSMC2 CTNNBIP1 CTNNBIP1 RSPO4 RSPO4 CSNK2A1 CSNK2A1 KREMEN2 KREMEN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX12Transcription factor SOX. (314 aa)
SOX15SRY-box transcription factor 15. (233 aa)
XPO1Exportin 1. (1091 aa)
CREBBPCREB binding protein. (2442 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
HMGXB3HMG-box containing 3. (1292 aa)
SOX18SRY-box transcription factor 18. (362 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (983 aa)
PYGO2Pygopus family PHD finger 2. (357 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
RSPO1R-spondin 1. (237 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSNLEP00000040983annotation not available (103 aa)
ENSNLEP00000040898Uncharacterized protein. (411 aa)
LOC100583243Histone H3; Belongs to the histone H3 family. (136 aa)
ENSNLEP00000040208AAA domain-containing protein. (406 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC7H2B clustered histone 7. (126 aa)
ENSNLEP00000041226ATPase_AAA_core domain-containing protein. (461 aa)
RNF146Ring finger protein 146. (359 aa)
RSPO3R-spondin 3. (292 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
LOC100599068Histone H3; Belongs to the histone H3 family. (136 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
ENSNLEP00000041604annotation not available (126 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
LOC100587665Histone H2B; Belongs to the histone H2B family. (126 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
LOC100591180Histone domain-containing protein. (136 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (455 aa)
DVL1Dishevelled segment polarity protein 1. (667 aa)
ENSNLEP00000042742Proteasome subunit alpha type. (233 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSNLEP00000043021annotation not available (136 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSNLEP00000043421Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (393 aa)
DVL2Dishevelled segment polarity protein 2. (713 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB2Proteasome subunit beta. (201 aa)
ENSNLEP00000044037Histone H2A; Belongs to the histone H2A family. (115 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
PSME4Proteasome activator subunit 4. (1821 aa)
ENSNLEP00000044711annotation not available (136 aa)
ENSNLEP00000044724Histone H2A; Belongs to the histone H2A family. (109 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3536 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
ENSNLEP00000044921annotation not available (103 aa)
ENSNLEP00000044923Uncharacterized protein. (553 aa)
ENSNLEP00000045034annotation not available (103 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSNLEP00000045113BTB domain-containing protein. (502 aa)
H2BC13Histone H2B; Belongs to the histone H2B family. (126 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
ENSNLEP00000046239Prot_ATP_ID_OB domain-containing protein. (183 aa)
PSMB7Proteasome subunit beta. (277 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (396 aa)
ENSNLEP00000046925annotation not available (103 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (397 aa)
ENSNLEP00000047148annotation not available (136 aa)
CUL3Cullin 3; Belongs to the cullin family. (744 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
TCF7HMG box domain-containing protein. (486 aa)
BIRC8Uncharacterized protein. (221 aa)
ENSNLEP00000047555Protein kinase domain-containing protein. (341 aa)
ENSNLEP00000047693annotation not available (136 aa)
LOC100593825Histone H3; Belongs to the histone H3 family. (136 aa)
ENSNLEP00000048056Uncharacterized protein. (115 aa)
DACT3Uncharacterized protein. (181 aa)
ENSNLEP00000048393VWFA domain-containing protein. (326 aa)
AXIN1Axin 1. (837 aa)
RSPO2R-spondin 2. (250 aa)
ENSNLEP00000049149annotation not available (103 aa)
ENSNLEP00000049245AAA domain-containing protein. (394 aa)
ENSNLEP00000049320annotation not available (130 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
H3C13Histone H3; Belongs to the histone H3 family. (136 aa)
PSME3Proteasome activator subunit 3. (239 aa)
ENSNLEP0000003956114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
TNKSPoly [ADP-ribose] polymerase. (1312 aa)
ENSNLEP00000039192Uncharacterized protein. (179 aa)
ENSNLEP00000039191annotation not available (136 aa)
ENSNLEP0000003917714_3_3 domain-containing protein; Belongs to the 14-3-3 family. (207 aa)
ENSNLEP00000039157CSN8_PSD8_EIF3K domain-containing protein. (225 aa)
ENSNLEP00000039110annotation not available (103 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (142 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038401ANK_REP_REGION domain-containing protein. (141 aa)
ENSNLEP00000038319annotation not available (126 aa)
ENSNLEP00000037880Uncharacterized protein. (341 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
ENSNLEP00000037453annotation not available (103 aa)
TLE4TLE family member 4, transcriptional corepressor. (790 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (535 aa)
PSMB6Proteasome subunit beta. (244 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
DKK1Dickkopf-like protein 1. (266 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (588 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSME2Proteasome activator subunit 2. (256 aa)
RBX1Ring-box 1. (108 aa)
EP300E1A binding protein p300. (2306 aa)
ENSNLEP00000035926Histone H2A; Belongs to the histone H2A family. (118 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (439 aa)
LEF1Lymphoid enhancer binding factor 1. (386 aa)
ENSNLEP00000034625annotation not available (103 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
LOC105740194Histone H2B; Belongs to the histone H2B family. (128 aa)
RNF43RING-type domain-containing protein. (783 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3797 aa)
LOC100595614Histone H2A; Belongs to the histone H2A family. (130 aa)
PSMB3Proteasome subunit beta. (205 aa)
SOX17SRY-box transcription factor 17. (410 aa)
PSMD9PDZ domain-containing protein. (222 aa)
TCF7L1Transcription factor 7 like 1. (517 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (528 aa)
APC2APC regulator of WNT signaling pathway 2. (1906 aa)
SOX4Transcription factor SOX. (459 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (638 aa)
TLE6TLE family member 6, subcortical maternal complex member. (553 aa)
ZNRF3Zinc and ring finger 3. (823 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (492 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
BTBD18BTB domain containing 18. (713 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
WIF1WNT inhibitory factor 1. (379 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
TLE1TLE family member 1, transcriptional corepressor. (765 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (320 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
RYKReceptor like tyrosine kinase. (525 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
SOX30SRY-box transcription factor 30. (753 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
G1QWQ9_NOMLEHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (607 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
PSMB10Proteasome subunit beta. (272 aa)
SOX5SRY-box transcription factor 5. (753 aa)
MEN1Menin 1. (614 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (424 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
SOSTSclerostin. (213 aa)
CTNNB1Catenin beta 1. (781 aa)
TLE7TLE family member 7. (441 aa)
SFRP2Secreted frizzled related protein 2. (280 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
KXD1KxDL motif containing 1. (195 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (227 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1117 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (585 aa)
LRP5LDL receptor related protein 5. (1510 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (345 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
BCL9LBCL9 like. (1338 aa)
ZBTB44Zinc finger and BTB domain containing 44. (570 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (572 aa)
ENSNLEP00000034023Histone H3; Belongs to the histone H3 family. (129 aa)
LOC100593400Histone H3; Belongs to the histone H3 family. (136 aa)
ENSNLEP00000033669annotation not available (103 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CSNK1G2Protein kinase domain-containing protein. (379 aa)
CXXC4CXXC finger protein 4. (371 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
H2BW1H2B histone family member W, testis specific; Belongs to the histone H2B family. (176 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1613 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1615 aa)
PSME1Proteasome activator subunit 1. (250 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (666 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
ENSNLEP00000031906Uncharacterized protein. (406 aa)
HIST2H2BEHistone H2B; Belongs to the histone H2B family. (126 aa)
TLE3TLE family member 3, transcriptional corepressor. (782 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSNLEP00000030887HMG box domain-containing protein. (318 aa)
LOC100592963annotation not available (136 aa)
ENSNLEP00000030555Protein kinase domain-containing protein. (200 aa)
ENSNLEP00000030482annotation not available (103 aa)
ENSNLEP00000029825Uncharacterized protein. (351 aa)
LOC100593203Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSNLEP00000029616RGS domain-containing protein. (169 aa)
ENSNLEP00000029611Proteasome subunit beta. (202 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LRP5LUncharacterized protein. (150 aa)
ENSNLEP00000029165Histone H2A; Belongs to the histone H2A family. (89 aa)
PSMA4Proteasome subunit alpha type. (241 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
ENSNLEP00000028499annotation not available (136 aa)
PSMA6Proteasome subunit alpha type. (206 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSNLEP00000028201annotation not available (136 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (488 aa)
AMER1Uncharacterized protein. (805 aa)
LOC100600196Histone domain-containing protein; Belongs to the histone H2B family. (125 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (628 aa)
SOX9SRY-box transcription factor 9. (510 aa)
LOC100591996Proteasome endopeptidase complex. (164 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSNLEP00000026915annotation not available (136 aa)
ENSNLEP00000026679annotation not available (136 aa)
ENSNLEP0000002662214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (230 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
ENSNLEP00000026115AAA domain-containing protein. (339 aa)
HIST1H2BKHistone H2B; Belongs to the histone H2B family. (126 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
ENSNLEP00000025948annotation not available (103 aa)
SOX1HMG box domain-containing protein. (251 aa)
LOC100597637Histone H3; Belongs to the histone H3 family. (136 aa)
ENSNLEP00000024590Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (479 aa)
PSMA1Proteasome subunit alpha type. (268 aa)
DVL3Dishevelled segment polarity protein 3. (673 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (232 aa)
SOX14SRY-box transcription factor 14. (240 aa)
SOX2SRY-box transcription factor 2. (319 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
SOX3SRY-box transcription factor 3. (446 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa)
LOC100596300Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
KLHL12Kelch like family member 12. (568 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (896 aa)
CDC73Cell division cycle 73. (531 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (929 aa)
SOX6SRY-box transcription factor 6. (829 aa)
G1S5F9_NOMLECalponin-homology (CH) domain-containing protein. (91 aa)
G1S5F4_NOMLEUncharacterized protein. (493 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (509 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
TCF7L2HMG box domain-containing protein. (534 aa)
PSMA7Proteasome subunit alpha type. (265 aa)
CBY1Chibby family member 1, beta catenin antagonist. (161 aa)
LOC100607246Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
SMURF2E3 ubiquitin-protein ligase. (745 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
AXIN2DIX domain-containing protein. (294 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
SLC39A13Solute carrier family 39 member 13. (332 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2579 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (548 aa)
G1RVW8_NOMLEUncharacterized protein. (281 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
SOX13SRY-box transcription factor 13. (622 aa)
HMGXB4HMG-box containing 4. (601 aa)
SOX8SRY-box transcription factor 8. (446 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
RSPO4R-spondin 4. (198 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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