STRINGSTRING
PTEN PTEN ENSNLEP00000049245 ENSNLEP00000049245 ENSNLEP00000049227 ENSNLEP00000049227 ENSNLEP00000048970 ENSNLEP00000048970 ENSNLEP00000048582 ENSNLEP00000048582 ENSNLEP00000048393 ENSNLEP00000048393 LOC100606243 LOC100606243 PSMD13 PSMD13 PSMB7 PSMB7 ENSNLEP00000046239 ENSNLEP00000046239 ENSNLEP00000045105 ENSNLEP00000045105 PSMD6 PSMD6 PSME4 PSME4 RPS27A RPS27A HLA-DQB1 HLA-DQB1 PSMB2 PSMB2 HLA-DQB2 HLA-DQB2 PSMD2 PSMD2 ENSNLEP00000042742 ENSNLEP00000042742 ENSNLEP00000042252 ENSNLEP00000042252 ENSNLEP00000042204 ENSNLEP00000042204 CD3E CD3E ENSNLEP00000041707 ENSNLEP00000041707 PSMD1 PSMD1 ENSNLEP00000041365 ENSNLEP00000041365 ENSNLEP00000041226 ENSNLEP00000041226 PSMB5 PSMB5 BCL10 BCL10 LOC100593010 LOC100593010 ENSNLEP00000040208 ENSNLEP00000040208 PSME3 PSME3 ENSNLEP00000039422 ENSNLEP00000039422 ENSNLEP00000039192 ENSNLEP00000039192 ENSNLEP00000039157 ENSNLEP00000039157 ENSNLEP00000038869 ENSNLEP00000038869 ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038401 ENSNLEP00000038401 ENSNLEP00000037880 ENSNLEP00000037880 ENSNLEP00000037583 ENSNLEP00000037583 PSMB6 PSMB6 PSMF1 PSMF1 RELA RELA PSME2 PSME2 ENSNLEP00000034619 ENSNLEP00000034619 PSMB1 PSMB1 PSMD7 PSMD7 ENSNLEP00000032399 ENSNLEP00000032399 PSME1 PSME1 PSMD14 PSMD14 PIK3R1 PIK3R1 ENSNLEP00000031906 ENSNLEP00000031906 PSMD10 PSMD10 ENSNLEP00000029825 ENSNLEP00000029825 ENSNLEP00000029811 ENSNLEP00000029811 FBXW11 FBXW11 ENSNLEP00000029611 ENSNLEP00000029611 PSMA4 PSMA4 HLA-DPA1 HLA-DPA1 PSMA6 PSMA6 PSMA5 PSMA5 PSMD12 PSMD12 ENSNLEP00000027432 ENSNLEP00000027432 CCDC71L CCDC71L ENSNLEP00000026115 ENSNLEP00000026115 CHUK CHUK MAP3K20 MAP3K20 PSMA1 PSMA1 RPS27A-2 RPS27A-2 TRAF6 TRAF6 PSMD5 PSMD5 PSMC1 PSMC1 PSMD8 PSMD8 PSMA7 PSMA7 TAB2 TAB2 BTRC BTRC CD247 CD247 PSMC3 PSMC3 IKBKG IKBKG PSMC4 PSMC4 MAP3K7 MAP3K7 NFKB1 NFKB1 PSMA3 PSMA3 IKBKB IKBKB PSMC6 PSMC6 PRKCQ PRKCQ CARD11 CARD11 PSMB4 PSMB4 PSMD4 PSMD4 LOC100592336 LOC100592336 PSMC2 PSMC2 MALT1 MALT1 INPP5D INPP5D SKP1 SKP1 CD3G CD3G CD3D CD3D HLA-DPB1 HLA-DPB1 PSMB9 PSMB9 PSMB8 PSMB8 HLA-DQA2 HLA-DQA2 HLA-DRA HLA-DRA PSMA8 PSMA8 KXD1 KXD1 PSMD11 PSMD11 PIK3R2 PIK3R2 PIK3CA PIK3CA UBE2N UBE2N PSMB10 PSMB10 CD4 CD4 PIK3CB PIK3CB PSMC5 PSMC5 TRAT1 TRAT1 NFKBIA NFKBIA CUL1 CUL1 PSMA2 PSMA2 G1QQJ2_NOMLE G1QQJ2_NOMLE LCK LCK RIPK2 RIPK2 PSMD3 PSMD3 PSMD9 PSMD9 PSMB3 PSMB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ENSNLEP00000049245AAA domain-containing protein. (394 aa)
ENSNLEP00000049227Uncharacterized protein. (122 aa)
ENSNLEP00000048970Ig-like domain-containing protein. (142 aa)
ENSNLEP00000048582DUF1968 domain-containing protein. (204 aa)
ENSNLEP00000048393VWFA domain-containing protein. (326 aa)
LOC100606243UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (188 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (397 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSNLEP00000046239Prot_ATP_ID_OB domain-containing protein. (183 aa)
ENSNLEP00000045105Ig-like domain-containing protein. (175 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSME4Proteasome activator subunit 4. (1821 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
PSMB2Proteasome subunit beta. (201 aa)
HLA-DQB2Major histocompatibility complex, class II, DQ beta 2. (264 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSNLEP00000042742Proteasome subunit alpha type. (233 aa)
ENSNLEP00000042252Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
ENSNLEP00000042204UBIQUITIN_CONJUGAT_2 domain-containing protein. (131 aa)
CD3ECD3e molecule. (198 aa)
ENSNLEP00000041707UBIQUITIN_CONJUGAT_2 domain-containing protein. (77 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
ENSNLEP00000041365Ig-like domain-containing protein. (298 aa)
ENSNLEP00000041226ATPase_AAA_core domain-containing protein. (461 aa)
PSMB5Proteasome subunit beta. (263 aa)
BCL10CARD domain-containing protein. (319 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
ENSNLEP00000040208AAA domain-containing protein. (406 aa)
PSME3Proteasome activator subunit 3. (239 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
ENSNLEP00000039192Uncharacterized protein. (179 aa)
ENSNLEP00000039157CSN8_PSD8_EIF3K domain-containing protein. (225 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038401ANK_REP_REGION domain-containing protein. (141 aa)
ENSNLEP00000037880Uncharacterized protein. (341 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
PSMB6Proteasome subunit beta. (244 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
PSME2Proteasome activator subunit 2. (256 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
ENSNLEP00000032399Uncharacterized protein. (628 aa)
PSME1Proteasome activator subunit 1. (250 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ENSNLEP00000031906Uncharacterized protein. (406 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSNLEP00000029825Uncharacterized protein. (351 aa)
ENSNLEP00000029811Uncharacterized protein; Belongs to the SKP1 family. (146 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
ENSNLEP00000029611Proteasome subunit beta. (202 aa)
PSMA4Proteasome subunit alpha type. (241 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
PSMA6Proteasome subunit alpha type. (206 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (488 aa)
ENSNLEP00000027432TNF receptor-associated factor. (488 aa)
CCDC71LUncharacterized protein. (293 aa)
ENSNLEP00000026115AAA domain-containing protein. (339 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
PSMA1Proteasome subunit alpha type. (268 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (509 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMA7Proteasome subunit alpha type. (265 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
CD247CD247 molecule. (163 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
IKBKGNEMO domain-containing protein. (173 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
MALT1MALT1 paracaspase. (824 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1209 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
CD3GCD3g molecule. (182 aa)
CD3DCD3d molecule. (153 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (276 aa)
HLA-DQA2Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
KXD1KxDL motif containing 1. (195 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PIK3R2Uncharacterized protein. (727 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PSMB10Proteasome subunit beta. (272 aa)
CD4CD4 molecule. (458 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (186 aa)
NFKBIANFKB inhibitor alpha. (305 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
G1QQJ2_NOMLEIg-like domain-containing protein. (128 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (528 aa)
PSMD9PDZ domain-containing protein. (222 aa)
PSMB3Proteasome subunit beta. (205 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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