STRINGSTRING
SDC4 SDC4 PLCG1 PLCG1 ITGA4 ITGA4 PIK3R2 PIK3R2 PIK3CA PIK3CA FNDC3B FNDC3B KRAS KRAS CD2 CD2 LRRIQ4 LRRIQ4 PTPN6 PTPN6 TREM1 TREM1 CSMD3 CSMD3 PIK3CB PIK3CB SLC16A1 SLC16A1 PPIA PPIA CD47 CD47 OLR1 OLR1 G1QRJ3_NOMLE G1QRJ3_NOMLE GRB14 GRB14 LCK LCK ITGB2 ITGB2 JAM2 JAM2 PROS1 PROS1 CXADR CXADR G1QLU1_NOMLE G1QLU1_NOMLE PTPN11 PTPN11 PPIL2 PPIL2 VPREB3 VPREB3 MIF MIF APOB APOB BSG BSG GRB7 GRB7 SDC3 SDC3 LYN LYN LOC100601497 LOC100601497 MERTK MERTK LOC100601152 LOC100601152 ESAM ESAM SRC SRC SLC7A10 SLC7A10 LOC100606651 LOC100606651 ENSNLEP00000047255 ENSNLEP00000047255 SLC3A2 SLC3A2 ENSNLEP00000046990 ENSNLEP00000046990 ENSNLEP00000046669 ENSNLEP00000046669 ENSNLEP00000046563 ENSNLEP00000046563 ENSNLEP00000046123 ENSNLEP00000046123 SLC7A5 SLC7A5 ENSNLEP00000044579 ENSNLEP00000044579 ENSNLEP00000044243 ENSNLEP00000044243 ENSNLEP00000044081 ENSNLEP00000044081 ENSNLEP00000043688 ENSNLEP00000043688 PF4 PF4 ENSNLEP00000042785 ENSNLEP00000042785 LOC100595271 LOC100595271 SPN SPN FYN FYN ANGPT1 ANGPT1 GRB2 GRB2 ENSNLEP00000040637 ENSNLEP00000040637 CD58 CD58 NRAS NRAS BCL3 BCL3 IGLV9-49 IGLV9-49 ENSNLEP00000039370 ENSNLEP00000039370 ENSNLEP00000039267 ENSNLEP00000039267 FNDC3A FNDC3A ATP1B3 ATP1B3 TSPAN7 TSPAN7 ENSNLEP00000038427 ENSNLEP00000038427 CSDE1 CSDE1 FCAMR FCAMR SELE SELE CSMD1 CSMD1 ENSNLEP00000037562 ENSNLEP00000037562 SELL SELL ENSNLEP00000037391 ENSNLEP00000037391 ITGA6 ITGA6 ENSNLEP00000036209 ENSNLEP00000036209 ITGAV ITGAV ENSNLEP00000035730 ENSNLEP00000035730 LOC100597420 LOC100597420 LOC100605369 LOC100605369 ENSNLEP00000034215 ENSNLEP00000034215 ENSNLEP00000033384 ENSNLEP00000033384 ENSNLEP00000032876 ENSNLEP00000032876 THBD THBD ENSNLEP00000032399 ENSNLEP00000032399 ITGB3 ITGB3 ENSNLEP00000032147 ENSNLEP00000032147 ENSNLEP00000032114 ENSNLEP00000032114 PROC PROC PIK3R1 PIK3R1 JAM3 JAM3 GPC1 GPC1 ITGB1 ITGB1 LOC100581919 LOC100581919 TNFRSF10D TNFRSF10D EPCAM EPCAM SDC2 SDC2 CEACAM6 CEACAM6 IGLV3-1 IGLV3-1 CSMD2 CSMD2 GYPA GYPA CD177 CD177 ENSNLEP00000027584 ENSNLEP00000027584 FCER1G FCER1G CD99L2 CD99L2 ENSNLEP00000025216 ENSNLEP00000025216 SDC1 SDC1 SLC7A6 SLC7A6 ENSNLEP00000024736 ENSNLEP00000024736 CD48 CD48 DOK2 DOK2 F11R F11R LENG9 LENG9 ERAS ERAS G1SAA2_NOMLE G1SAA2_NOMLE TACSTD2 TACSTD2 CD44 CD44 ITGA5 ITGA5 SOS1 SOS1 G1S356_NOMLE G1S356_NOMLE ITGAX ITGAX TEK TEK ITGAM ITGAM TNFRSF10A TNFRSF10A G1S167_NOMLE G1S167_NOMLE ITGAL ITGAL COL1A2 COL1A2 G1RZR5_NOMLE G1RZR5_NOMLE G1RZR1_NOMLE G1RZR1_NOMLE VPREB1 VPREB1 PECAM1 PECAM1 SLC16A8 SLC16A8 PICK1 PICK1 SELP SELP SLC7A8 SLC7A8 ATP1B1 ATP1B1 ANGPT2 ANGPT2 SLC7A7 SLC7A7 F2 F2 SLC16A3 SLC16A3 SLC7A11 SLC7A11 CD244 CD244 TGFB1 TGFB1 CD84 CD84 L1CAM L1CAM G1RT88_NOMLE G1RT88_NOMLE CEACAM5 CEACAM5 TIE1 TIE1 SLAMF8 SLAMF8 SHC1 SHC1 MAG MAG CEACAM8 CEACAM8 CEACAM1 CEACAM1 GP6 GP6 GAS6 GAS6 CD74 CD74 PROCR PROCR ATP1B2 ATP1B2 ANGPTL7 ANGPTL7 ANGPT4 ANGPT4 SIRPD SIRPD SIRPG SIRPG SIRPA SIRPA COL1A1 COL1A1 ITGA3 ITGA3 HRAS HRAS INPP5D INPP5D GLG1 GLG1 PF4V1 PF4V1 JCHAIN JCHAIN SLC7A9 SLC7A9 VSIG2 VSIG2 JAML JAML FN1 FN1 MMP1 MMP1 CEACAM16 CEACAM16 YES1 YES1 SELPLG SELPLG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
PIK3R2Uncharacterized protein. (727 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CD2CD2 molecule. (351 aa)
LRRIQ4Leucine rich repeats and IQ motif containing 4. (560 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (627 aa)
TREM1Triggering receptor expressed on myeloid cells 1. (234 aa)
CSMD3CUB and Sushi multiple domains 3. (3707 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
SLC16A1Solute carrier family 16 member 1. (500 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
CD47CD47 molecule. (323 aa)
OLR1Oxidized low density lipoprotein receptor 1. (273 aa)
G1QRJ3_NOMLEUncharacterized protein. (103 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
ITGB2Integrin beta. (762 aa)
JAM2Junctional adhesion molecule 2. (312 aa)
PROS1Protein S. (676 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
G1QLU1_NOMLEUncharacterized protein. (426 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
PPIL2Peptidylprolyl isomerase like 2. (502 aa)
VPREB3V-set pre-B cell surrogate light chain 3. (123 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
APOBApolipoprotein B. (4559 aa)
BSGUncharacterized protein. (345 aa)
GRB7Growth factor receptor bound protein 7. (476 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (405 aa)
LYNTyrosine-protein kinase. (512 aa)
LOC100601497Uncharacterized protein. (253 aa)
MERTKMER proto-oncogene, tyrosine kinase. (991 aa)
LOC100601152Uncharacterized protein. (457 aa)
ESAMEndothelial cell adhesion molecule. (386 aa)
SRCTyrosine-protein kinase. (537 aa)
SLC7A10Solute carrier family 7 member 10. (516 aa)
LOC100606651Uncharacterized protein. (502 aa)
ENSNLEP00000047255Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa)
SLC3A2Solute carrier family 3 member 2. (624 aa)
ENSNLEP00000046990Ig-like domain-containing protein. (137 aa)
ENSNLEP00000046669Ig-like domain-containing protein. (169 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
ENSNLEP00000046123Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa)
SLC7A5Solute carrier family 7 member 5. (507 aa)
ENSNLEP00000044579Ig-like domain-containing protein. (148 aa)
ENSNLEP00000044243IGv domain-containing protein. (199 aa)
ENSNLEP00000044081Ig-like domain-containing protein. (147 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
PF4C-X-C motif chemokine. (106 aa)
ENSNLEP00000042785Ig-like domain-containing protein. (180 aa)
LOC100595271Uncharacterized protein. (253 aa)
SPNSialophorin. (400 aa)
FYNTyrosine-protein kinase. (537 aa)
ANGPT1Angiopoietin 1. (498 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSNLEP00000040637Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
CD58CD58 molecule. (250 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
BCL3BCL3 transcription coactivator. (453 aa)
IGLV9-49Immunoglobulin lambda variable 9-49. (122 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
ENSNLEP00000039267Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (234 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ATP1B3Uncharacterized protein. (89 aa)
TSPAN7Tetraspanin. (266 aa)
ENSNLEP00000038427Uncharacterized protein. (305 aa)
CSDE1Cold shock domain containing E1. (844 aa)
FCAMRFc fragment of IgA and IgM receptor. (577 aa)
SELESelectin E. (612 aa)
CSMD1CUB and Sushi multiple domains 1. (3565 aa)
ENSNLEP00000037562Uncharacterized protein. (419 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
ENSNLEP00000037391Uncharacterized protein. (52 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ENSNLEP00000036209Ig-like domain-containing protein. (151 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1008 aa)
ENSNLEP00000035730Ig-like domain-containing protein. (178 aa)
LOC100597420Uncharacterized protein. (438 aa)
LOC100605369Uncharacterized protein. (571 aa)
ENSNLEP00000034215Ig-like domain-containing protein. (168 aa)
ENSNLEP00000033384Ig-like domain-containing protein. (161 aa)
ENSNLEP00000032876Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa)
THBDThrombomodulin. (568 aa)
ENSNLEP00000032399Uncharacterized protein. (628 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
ENSNLEP00000032147Uncharacterized protein. (3186 aa)
ENSNLEP00000032114Ig-like domain-containing protein. (161 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa; Belongs to the peptidase S1 family. (457 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
JAM3Junctional adhesion molecule 3. (275 aa)
GPC1Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (465 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LOC100581919Uncharacterized protein. (96 aa)
TNFRSF10DUncharacterized protein. (226 aa)
EPCAMEpithelial cell adhesion molecule. (320 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
CEACAM6Carcinoembryonic antigen related cell adhesion molecule 6. (310 aa)
IGLV3-1Immunoglobulin lambda variable 3-1. (116 aa)
CSMD2CUB and Sushi multiple domains 2. (3507 aa)
GYPAGlycophorin. (118 aa)
CD177Uncharacterized protein. (140 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
FCER1GUncharacterized protein. (112 aa)
CD99L2CD99 molecule like 2. (258 aa)
ENSNLEP00000025216Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (256 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
SLC7A6Solute carrier family 7 member 6. (467 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
CD48CD48 molecule. (252 aa)
DOK2Docking protein 2. (412 aa)
F11RF11 receptor. (299 aa)
LENG9Leukocyte receptor cluster member 9. (445 aa)
ERASES cell expressed Ras. (233 aa)
G1SAA2_NOMLEIg-like domain-containing protein. (111 aa)
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)
CD44CD44 molecule (Indian blood group). (742 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1038 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
G1S356_NOMLEIg-like domain-containing protein. (130 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1153 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (992 aa)
TNFRSF10ATNF receptor superfamily member 10a. (471 aa)
G1S167_NOMLEUncharacterized protein. (410 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1142 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
G1RZR5_NOMLEIg-like domain-containing protein. (144 aa)
G1RZR1_NOMLEIg-like domain-containing protein. (148 aa)
VPREB1V-set pre-B cell surrogate light chain 1. (145 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (721 aa)
SLC16A8Solute carrier family 16 member 8. (504 aa)
PICK1Protein interacting with PRKCA 1. (415 aa)
SELPSelectin P. (830 aa)
SLC7A8Solute carrier family 7 member 8. (540 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ANGPT2Angiopoietin 2. (496 aa)
SLC7A7Solute carrier family 7 member 7. (511 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (613 aa)
SLC16A3Solute carrier family 16 member 3. (465 aa)
SLC7A11Solute carrier family 7 member 11. (500 aa)
CD244CD244 molecule. (370 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CD84CD84 molecule. (339 aa)
L1CAML1 cell adhesion molecule. (1174 aa)
G1RT88_NOMLEIGv domain-containing protein. (232 aa)
CEACAM5Carcinoembryonic antigen related cell adhesion molecule 5. (691 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1142 aa)
SLAMF8SLAM family member 8. (249 aa)
SHC1SHC adaptor protein 1. (542 aa)
MAGUncharacterized protein. (58 aa)
CEACAM8Carcinoembryonic antigen related cell adhesion molecule 8. (300 aa)
CEACAM1Uncharacterized protein. (493 aa)
GP6Ig-like domain-containing protein. (222 aa)
GAS6Growth arrest specific 6. (679 aa)
CD74CD74 molecule. (296 aa)
PROCRProtein C receptor. (233 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ANGPTL7Angiopoietin like 7. (343 aa)
ANGPT4Angiopoietin 4. (480 aa)
SIRPDSignal regulatory protein delta. (197 aa)
SIRPGSignal regulatory protein gamma. (354 aa)
SIRPAUncharacterized protein. (486 aa)
COL1A1Collagen type I alpha 1 chain. (1386 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1050 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1209 aa)
GLG1Golgi glycoprotein 1. (1104 aa)
PF4V1C-X-C motif chemokine. (101 aa)
JCHAINJoining chain of multimeric IgA and IgM. (159 aa)
SLC7A9Solute carrier family 7 member 9. (521 aa)
VSIG2V-set and immunoglobulin domain containing 2. (327 aa)
JAMLJunction adhesion molecule like. (394 aa)
FN1Fibronectin 1. (2477 aa)
MMP1Matrix metallopeptidase 1. (470 aa)
CEACAM16Carcinoembryonic antigen related cell adhesion molecule 16. (440 aa)
YES1Tyrosine-protein kinase. (519 aa)
SELPLGSelectin P ligand. (428 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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