STRINGSTRING
M3ZAQ1_NOMLE M3ZAQ1_NOMLE ENSNLEP00000024646 ENSNLEP00000024646 DSTN DSTN CFL1 CFL1 HSP90AA1 HSP90AA1 MYO1C MYO1C ENSNLEP00000026528 ENSNLEP00000026528 VAV1 VAV1 MAPK1 MAPK1 HSP90AB1 HSP90AB1 ENSNLEP00000027935 ENSNLEP00000027935 IGLV3-1 IGLV3-1 ACTR2 ACTR2 CYFIP2 CYFIP2 SYK SYK CYFIP1 CYFIP1 ENSNLEP00000030621 ENSNLEP00000030621 ENSNLEP00000030682 ENSNLEP00000030682 PIK3R1 PIK3R1 ENSNLEP00000032002 ENSNLEP00000032002 ENSNLEP00000032114 ENSNLEP00000032114 ENSNLEP00000032399 ENSNLEP00000032399 ENSNLEP00000033007 ENSNLEP00000033007 ENSNLEP00000033384 ENSNLEP00000033384 BAIAP2 BAIAP2 FGR FGR NCKAP1L NCKAP1L ITPR2 ITPR2 ENSNLEP00000034215 ENSNLEP00000034215 ELMO2 ELMO2 PTK2 PTK2 ENSNLEP00000034648 ENSNLEP00000034648 NCKAP1 NCKAP1 WASHC1 WASHC1 FMN1 FMN1 ENSNLEP00000035379 ENSNLEP00000035379 ENSNLEP00000035534 ENSNLEP00000035534 ENSNLEP00000035684 ENSNLEP00000035684 ENSNLEP00000035730 ENSNLEP00000035730 LIMK1 LIMK1 LOC100603674 LOC100603674 ENSNLEP00000036209 ENSNLEP00000036209 ENSNLEP00000036326 ENSNLEP00000036326 SRC SRC ENSNLEP00000048482 ENSNLEP00000048482 ENSNLEP00000048240 ENSNLEP00000048240 VAV2 VAV2 LOC100593698 LOC100593698 MYO5A MYO5A ENSNLEP00000046990 ENSNLEP00000046990 ENSNLEP00000046669 ENSNLEP00000046669 ARPC4 ARPC4 ENSNLEP00000045542 ENSNLEP00000045542 MYO1D MYO1D ACTRT2 ACTRT2 ARPC2 ARPC2 ENSNLEP00000044579 ENSNLEP00000044579 ENSNLEP00000044081 ENSNLEP00000044081 ENSNLEP00000043131 ENSNLEP00000043131 ENSNLEP00000043017 ENSNLEP00000043017 ENSNLEP00000042785 ENSNLEP00000042785 ENSNLEP00000042609 ENSNLEP00000042609 PLD1 PLD1 ABI1 ABI1 PLPP5 PLPP5 ENSNLEP00000041102 ENSNLEP00000041102 FYN FYN CDC42 CDC42 GRB2 GRB2 PLPP4 PLPP4 IGLV9-49 IGLV9-49 ITPR3 ITPR3 MYO1A MYO1A PAK1 PAK1 ENSNLEP00000038443 ENSNLEP00000038443 ACTB ACTB ENSNLEP00000037391 ENSNLEP00000037391 ENSNLEP00000037385 ENSNLEP00000037385 PLA2G6 PLA2G6 DOCK1 DOCK1 CRK CRK LYN LYN VAV3 VAV3 MYO1H MYO1H WIPF2 WIPF2 MAPK3 MAPK3 ELMO1 ELMO1 ARPC3 ARPC3 NF2 NF2 CFL2 CFL2 AHCYL1 AHCYL1 FMN2 FMN2 ITPR1 ITPR1 PLD5 PLD5 MYO1G MYO1G NCK1 NCK1 PIK3CB PIK3CB ELMO3 ELMO3 MYO9B MYO9B PIK3CA PIK3CA WIPF1 WIPF1 PIK3R2 PIK3R2 PLCG1 PLCG1 MYO5C MYO5C NCKIPSD NCKIPSD MYO1B MYO1B YES1 YES1 ABI2 ABI2 PRKCD PRKCD CD3G CD3G BTK BTK ACTL8 ACTL8 WAS WAS WASF2 WASF2 HCK HCK MYH2 MYH2 PLCG2 PLCG2 ARPC1A ARPC1A ARPC1B ARPC1B ACTR3 ACTR3 MYO10 MYO10 WASL WASL ABL1 ABL1 WASF1 WASF1 WASF3 WASF3 PLD3 PLD3 FCGR2A FCGR2A MYH9 MYH9 CD247 CD247 G1RYM0_NOMLE G1RYM0_NOMLE G1RZR1_NOMLE G1RZR1_NOMLE G1RZR5_NOMLE G1RZR5_NOMLE ACTR3B ACTR3B RAC1 RAC1 G1S356_NOMLE G1S356_NOMLE PRKCE PRKCE ARPC5L ARPC5L PLD2 PLD2 ARPC5 ARPC5 G1SAA2_NOMLE G1SAA2_NOMLE ACTL7B ACTL7B ACTL7A ACTL7A ACTL9 ACTL9 ACTG1 ACTG1 M3Z9E6_NOMLE M3Z9E6_NOMLE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3ZAQ1_NOMLEIg-like domain-containing protein. (204 aa)
ENSNLEP00000024646Uncharacterized protein. (137 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (197 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (853 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1023 aa)
ENSNLEP00000026528Uncharacterized protein. (337 aa)
VAV1Uncharacterized protein. (739 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (665 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
IGLV3-1Immunoglobulin lambda variable 3-1. (116 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
SYKTyrosine-protein kinase. (532 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1228 aa)
ENSNLEP00000030621WD_REPEATS_REGION domain-containing protein. (322 aa)
ENSNLEP00000030682Ig-like domain-containing protein. (159 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ENSNLEP00000032002ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (116 aa)
ENSNLEP00000032114Ig-like domain-containing protein. (161 aa)
ENSNLEP00000032399Uncharacterized protein. (628 aa)
ENSNLEP00000033007Uncharacterized protein; Belongs to the actin family. (312 aa)
ENSNLEP00000033384Ig-like domain-containing protein. (161 aa)
BAIAP2BAI1 associated protein 2. (561 aa)
FGRTyrosine-protein kinase. (476 aa)
NCKAP1LNCK associated protein 1 like. (1109 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
ENSNLEP00000034215Ig-like domain-containing protein. (168 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
ENSNLEP00000034648ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (210 aa)
NCKAP1NCK associated protein 1. (1134 aa)
WASHC1WASH complex subunit 1. (498 aa)
FMN1Formin 1. (1424 aa)
ENSNLEP00000035379HATPase_c domain-containing protein. (297 aa)
ENSNLEP00000035534ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (189 aa)
ENSNLEP00000035684WD_REPEATS_REGION domain-containing protein. (199 aa)
ENSNLEP00000035730Ig-like domain-containing protein. (178 aa)
LIMK1Uncharacterized protein. (614 aa)
LOC100603674Uncharacterized protein. (371 aa)
ENSNLEP00000036209Ig-like domain-containing protein. (151 aa)
ENSNLEP00000036326Uncharacterized protein. (321 aa)
SRCTyrosine-protein kinase. (537 aa)
ENSNLEP00000048482Zf-piccolo domain-containing protein. (615 aa)
ENSNLEP00000048240ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (164 aa)
VAV2Vav guanine nucleotide exchange factor 2. (788 aa)
LOC100593698Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (172 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1867 aa)
ENSNLEP00000046990Ig-like domain-containing protein. (137 aa)
ENSNLEP00000046669Ig-like domain-containing protein. (169 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (187 aa)
ENSNLEP00000045542Ig-like domain-containing protein. (115 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (369 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (275 aa)
ENSNLEP00000044579Ig-like domain-containing protein. (148 aa)
ENSNLEP00000044081Ig-like domain-containing protein. (147 aa)
ENSNLEP00000043131Ig-like domain-containing protein. (186 aa)
ENSNLEP00000043017HATPase_c domain-containing protein. (648 aa)
ENSNLEP00000042785Ig-like domain-containing protein. (180 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
PLD1Phospholipase. (1074 aa)
ABI1Abl interactor 1. (508 aa)
PLPP5Phospholipid phosphatase 5. (267 aa)
ENSNLEP00000041102ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (151 aa)
FYNTyrosine-protein kinase. (537 aa)
CDC42Cell division cycle 42. (191 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PLPP4Phospholipid phosphatase 4. (279 aa)
IGLV9-49Immunoglobulin lambda variable 9-49. (122 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2755 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (900 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ENSNLEP00000038443Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (154 aa)
ACTBUncharacterized protein. (363 aa)
ENSNLEP00000037391Uncharacterized protein. (52 aa)
ENSNLEP00000037385Uncharacterized protein. (437 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
CRKUncharacterized protein. (252 aa)
LYNTyrosine-protein kinase. (512 aa)
VAV3Vav guanine nucleotide exchange factor 3. (799 aa)
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1029 aa)
WIPF2WH2 domain-containing protein. (182 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (163 aa)
NF2Neurofibromin 2. (595 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (529 aa)
FMN2Formin 2. (1613 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
PLD5Phospholipase D family member 5. (489 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
NCK1Cytoplasmic protein. (377 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
ELMO3Engulfment and cell motility 3. (694 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2151 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
WIPF1WAS/WASL interacting protein family member 1. (510 aa)
PIK3R2Uncharacterized protein. (727 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
MYO5CMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1712 aa)
NCKIPSDNCK interacting protein with SH3 domain. (657 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1117 aa)
YES1Tyrosine-protein kinase. (519 aa)
ABI2Abl interactor 2. (462 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CD3GCD3g molecule. (182 aa)
BTKTyrosine-protein kinase. (659 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
WASWASP actin nucleation promoting factor. (502 aa)
WASF2WH2 domain-containing protein. (401 aa)
HCKTyrosine-protein kinase. (525 aa)
MYH2Myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BWD_REPEATS_REGION domain-containing protein. (598 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (417 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2031 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
WASF1WASP family member 1. (547 aa)
WASF3WASP family member 3. (502 aa)
PLD3Phospholipase D family member 3. (512 aa)
FCGR2AFc fragment of IgG receptor IIa. (317 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
CD247CD247 molecule. (163 aa)
G1RYM0_NOMLEWH2 domain-containing protein. (421 aa)
G1RZR1_NOMLEIg-like domain-containing protein. (148 aa)
G1RZR5_NOMLEIg-like domain-containing protein. (144 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (303 aa)
RAC1Rac family small GTPase 1. (187 aa)
G1S356_NOMLEIg-like domain-containing protein. (130 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
PLD2Phospholipase. (933 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
G1SAA2_NOMLEIg-like domain-containing protein. (111 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTL9Actin like 9; Belongs to the actin family. (416 aa)
ACTG1Actin gamma 1. (378 aa)
M3Z9E6_NOMLEIg-like domain-containing protein. (148 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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