STRINGSTRING
INPP5D INPP5D PLCG1 PLCG1 FNDC3B FNDC3B PTPN6 PTPN6 LCK LCK LYN LYN PTPN11 PTPN11 ENSNLEP00000024736 ENSNLEP00000024736 ENSNLEP00000027584 ENSNLEP00000027584 ITGB3 ITGB3 LOC100605369 LOC100605369 ITGAV ITGAV FNDC3A FNDC3A FYN FYN ENSNLEP00000043688 ENSNLEP00000043688 SRC SRC PECAM1 PECAM1 YES1 YES1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INPP5DInositol polyphosphate-5-phosphatase D. (1209 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (627 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
LYNTyrosine-protein kinase. (512 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
LOC100605369Uncharacterized protein. (571 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1008 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
SRCTyrosine-protein kinase. (537 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (721 aa)
YES1Tyrosine-protein kinase. (519 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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