44 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	TREM2	Ig-like domain-containing protein. (222 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	LOC100597906	Uncharacterized protein. (263 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
	BTK	Tyrosine-protein kinase. (659 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
	SIGLEC15	Sialic acid binding Ig like lectin 15. (328 aa)
	ENSNLEP00000042609	Uncharacterized protein. (168 aa)
	LAT	Linker for activation of T cells. (264 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	TYROBP	Uncharacterized protein. (144 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	ENSNLEP00000039370	SH2 domain-containing protein. (299 aa)
	SHC1	SHC adaptor protein 1. (542 aa)
	RAC1	Rac family small GTPase 1. (187 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
	ERAS	ES cell expressed Ras. (233 aa)
	KLRK1	Killer cell lectin like receptor K1. (216 aa)
	ENSNLEP00000027935	Uncharacterized protein. (181 aa)
	LOC100595088	Uncharacterized protein. (398 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
	ENSNLEP00000032399	Uncharacterized protein. (628 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (460 aa)
	CSDE1	Cold shock domain containing E1. (844 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
	GRAP2	GRB2 related adaptor protein 2. (330 aa)
	SPNS1	Sphingolipid transporter 1 (putative). (476 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (788 aa)
	LCP2	Lymphocyte cytosolic protein 2. (533 aa)
	NCR2	Natural cytotoxicity triggering receptor 2. (277 aa)
	ENSNLEP00000046563	Uncharacterized protein. (498 aa)
	CD300E	IG domain-containing protein. (135 aa)
	SYK	Tyrosine-protein kinase. (532 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (799 aa)
	CD300LB	Uncharacterized protein. (159 aa)
	CLEC5A	C-type lectin domain containing 5A. (188 aa)
	LCK	LCK proto-oncogene, Src family tyrosine kinase. (448 aa)
	KLRC1	Killer cell lectin like receptor C1. (233 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
	TREM1	Triggering receptor expressed on myeloid cells 1. (234 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	TYROBP	ENSNLEP00000037660	ENSNLEP00000040666	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein.	0.492
BTK	ENSNLEP00000039370	ENSNLEP00000009167	ENSNLEP00000039370	Tyrosine-protein kinase.	SH2 domain-containing protein.	0.527
BTK	ENSNLEP00000046563	ENSNLEP00000009167	ENSNLEP00000046563	Tyrosine-protein kinase.	Uncharacterized protein.	0.527
BTK	FYN	ENSNLEP00000009167	ENSNLEP00000041056	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.673
BTK	GRAP2	ENSNLEP00000009167	ENSNLEP00000036468	Tyrosine-protein kinase.	GRB2 related adaptor protein 2.	0.824
BTK	GRB2	ENSNLEP00000009167	ENSNLEP00000040743	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.874
BTK	HRAS	ENSNLEP00000009167	ENSNLEP00000010109	Tyrosine-protein kinase.	HRas proto-oncogene, GTPase.	0.471
BTK	KLRK1	ENSNLEP00000009167	ENSNLEP00000025971	Tyrosine-protein kinase.	Killer cell lectin like receptor K1.	0.411
BTK	LAT	ENSNLEP00000009167	ENSNLEP00000041111	Tyrosine-protein kinase.	Linker for activation of T cells.	0.576
BTK	LCK	ENSNLEP00000009167	ENSNLEP00000002978	Tyrosine-protein kinase.	LCK proto-oncogene, Src family tyrosine kinase.	0.581
BTK	LCP2	ENSNLEP00000009167	ENSNLEP00000047802	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.925
BTK	PIK3CA	ENSNLEP00000009167	ENSNLEP00000006936	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.549
BTK	PIK3CB	ENSNLEP00000009167	ENSNLEP00000005291	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.526
BTK	PIK3R1	ENSNLEP00000009167	ENSNLEP00000031935	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.563
BTK	PIK3R2	ENSNLEP00000009167	ENSNLEP00000007175	Tyrosine-protein kinase.	Uncharacterized protein.	0.419
BTK	PLCG1	ENSNLEP00000009167	ENSNLEP00000007890	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.686
BTK	PLCG2	ENSNLEP00000009167	ENSNLEP00000012984	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.961
BTK	SHC1	ENSNLEP00000009167	ENSNLEP00000014019	Tyrosine-protein kinase.	SHC adaptor protein 1.	0.527
BTK	SOS1	ENSNLEP00000009167	ENSNLEP00000019976	Tyrosine-protein kinase.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.492
BTK	SYK	ENSNLEP00000009167	ENSNLEP00000000530	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.917

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