STRINGSTRING
NEDD4L NEDD4L ENSNLEP00000043312 ENSNLEP00000043312 ENSNLEP00000043421 ENSNLEP00000043421 RPS27A RPS27A SKIL SKIL SMAD7 SMAD7 SMURF2 SMURF2 NCOR1 NCOR1 PARP1 PARP1 PPM1A PPM1A UBE2D1 UBE2D1 SMAD4 SMAD4 RNF111 RNF111 TGIF2 TGIF2 TRIM33 TRIM33 WWTR1 WWTR1 HDAC1 HDAC1 NCOR2 NCOR2 MAPK3 MAPK3 ATP1B4 ATP1B4 RPS27A-2 RPS27A-2 SMAD2 SMAD2 USP9X USP9X ENSNLEP00000027025 ENSNLEP00000027025 MAPK1 MAPK1 SNW1 SNW1 TGIF1 TGIF1 STAT1 STAT1 ENSNLEP00000034619 ENSNLEP00000034619 ENSNLEP00000036789 ENSNLEP00000036789 ENSNLEP00000037583 ENSNLEP00000037583 ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038869 ENSNLEP00000038869 SMAD3 SMAD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEDD4LUncharacterized protein. (1236 aa)
ENSNLEP00000043312Homeobox domain-containing protein. (242 aa)
ENSNLEP00000043421Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (393 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
SKILSKI like proto-oncogene. (683 aa)
SMAD7Mothers against decapentaplegic homolog. (376 aa)
SMURF2E3 ubiquitin-protein ligase. (745 aa)
NCOR1Nuclear receptor corepressor 1. (2442 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (948 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
RNF111Ring finger protein 111. (995 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
TRIM33Tripartite motif containing 33. (1002 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
NCOR2Nuclear receptor corepressor 2. (2373 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2507 aa)
ENSNLEP00000027025PPM-type phosphatase domain-containing protein. (340 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
SNW1SNW domain containing 1. (571 aa)
TGIF1TGFB induced factor homeobox 1. (400 aa)
STAT1Signal transducer and activator of transcription. (780 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
ENSNLEP00000036789SKIP_SNW domain-containing protein. (443 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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