34 items (Nomascus leucogenys) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	NEDD4L	Uncharacterized protein. (1236 aa)
	ENSNLEP00000043312	Homeobox domain-containing protein. (242 aa)
	ENSNLEP00000043421	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (393 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (161 aa)
	SKIL	SKI like proto-oncogene. (683 aa)
	SMAD7	Mothers against decapentaplegic homolog. (376 aa)
	SMURF2	E3 ubiquitin-protein ligase. (745 aa)
	NCOR1	Nuclear receptor corepressor 1. (2442 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (948 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	UBE2D1	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	RNF111	Ring finger protein 111. (995 aa)
	TGIF2	TGFB induced factor homeobox 2. (237 aa)
	TRIM33	Tripartite motif containing 33. (1002 aa)
	WWTR1	WW domain containing transcription regulator 1. (400 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	NCOR2	Nuclear receptor corepressor 2. (2373 aa)
	MAPK3	Mitogen-activated protein kinase. (278 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
	RPS27A-2	Ubiquitin-like domain-containing protein. (156 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	USP9X	Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2507 aa)
	ENSNLEP00000027025	PPM-type phosphatase domain-containing protein. (340 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
	SNW1	SNW domain containing 1. (571 aa)
	TGIF1	TGFB induced factor homeobox 1. (400 aa)
	STAT1	Signal transducer and activator of transcription. (780 aa)
	ENSNLEP00000034619	Ubiquitin-like domain-containing protein. (77 aa)
	ENSNLEP00000036789	SKIP_SNW domain-containing protein. (443 aa)
	ENSNLEP00000037583	Ubiquitin-like domain-containing protein. (79 aa)
	ENSNLEP00000038579	Ubiquitin-like domain-containing protein. (104 aa)
	ENSNLEP00000038869	Ubiquitin-like domain-containing protein. (156 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1B4	ENSNLEP00000036789	ENSNLEP00000018196	ENSNLEP00000036789	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SKIP_SNW domain-containing protein.	0.600
ATP1B4	MAPK1	ENSNLEP00000018196	ENSNLEP00000027273	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.900
ATP1B4	SMAD7	ENSNLEP00000018196	ENSNLEP00000048725	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mothers against decapentaplegic homolog.	0.628
ATP1B4	SNW1	ENSNLEP00000018196	ENSNLEP00000029083	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SNW domain containing 1.	0.600
ENSNLEP00000027025	ENSNLEP00000034619	ENSNLEP00000027025	ENSNLEP00000034619	PPM-type phosphatase domain-containing protein.	Ubiquitin-like domain-containing protein.	0.446
ENSNLEP00000027025	SMAD2	ENSNLEP00000027025	ENSNLEP00000023604	PPM-type phosphatase domain-containing protein.	Mothers against decapentaplegic homolog.	0.719
ENSNLEP00000027025	SMAD3	ENSNLEP00000027025	ENSNLEP00000041430	PPM-type phosphatase domain-containing protein.	Mothers against decapentaplegic homolog.	0.688
ENSNLEP00000027025	SMAD4	ENSNLEP00000027025	ENSNLEP00000014415	PPM-type phosphatase domain-containing protein.	Mothers against decapentaplegic homolog.	0.583
ENSNLEP00000027025	SMAD7	ENSNLEP00000027025	ENSNLEP00000048725	PPM-type phosphatase domain-containing protein.	Mothers against decapentaplegic homolog.	0.437
ENSNLEP00000034619	ENSNLEP00000027025	ENSNLEP00000034619	ENSNLEP00000027025	Ubiquitin-like domain-containing protein.	PPM-type phosphatase domain-containing protein.	0.446
ENSNLEP00000034619	ENSNLEP00000037583	ENSNLEP00000034619	ENSNLEP00000037583	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.927
ENSNLEP00000034619	ENSNLEP00000038579	ENSNLEP00000034619	ENSNLEP00000038579	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.927
ENSNLEP00000034619	ENSNLEP00000038869	ENSNLEP00000034619	ENSNLEP00000038869	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.845
ENSNLEP00000034619	NCOR1	ENSNLEP00000034619	ENSNLEP00000017988	Ubiquitin-like domain-containing protein.	Nuclear receptor corepressor 1.	0.484
ENSNLEP00000034619	NCOR2	ENSNLEP00000034619	ENSNLEP00000002872	Ubiquitin-like domain-containing protein.	Nuclear receptor corepressor 2.	0.484
ENSNLEP00000034619	NEDD4L	ENSNLEP00000034619	ENSNLEP00000043221	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.860
ENSNLEP00000034619	PARP1	ENSNLEP00000034619	ENSNLEP00000016881	Ubiquitin-like domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.592
ENSNLEP00000034619	PPM1A	ENSNLEP00000034619	ENSNLEP00000016647	Ubiquitin-like domain-containing protein.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.446
ENSNLEP00000034619	RNF111	ENSNLEP00000034619	ENSNLEP00000014030	Ubiquitin-like domain-containing protein.	Ring finger protein 111.	0.709
ENSNLEP00000034619	RPS27A	ENSNLEP00000034619	ENSNLEP00000044522	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.846

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