STRINGSTRING
E2F5 E2F5 MAPK3 MAPK3 LOC100602359 LOC100602359 TFDP1 TFDP1 CCNK CCNK ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000037583 ENSNLEP00000037583 EP300 EP300 JUNB JUNB ENSNLEP00000034619 ENSNLEP00000034619 TGIF1 TGIF1 CCNT2 CCNT2 MAPK1 MAPK1 ENSNLEP00000025225 ENSNLEP00000025225 SMAD2 SMAD2 RPS27A-2 RPS27A-2 SMAD7 SMAD7 CDKN2B CDKN2B ENSNLEP00000046336 ENSNLEP00000046336 RPS27A RPS27A ENSNLEP00000044256 ENSNLEP00000044256 ENSNLEP00000044164 ENSNLEP00000044164 ENSNLEP00000043660 ENSNLEP00000043660 ENSNLEP00000043421 ENSNLEP00000043421 ENSNLEP00000043312 ENSNLEP00000043312 TFDP2 TFDP2 SMAD3 SMAD3 CCNC CCNC ENSNLEP00000039422 ENSNLEP00000039422 ENSNLEP00000038869 ENSNLEP00000038869 CCNT1 CCNT1 SP1 SP1 CDK9 CDK9 COL1A2 COL1A2 CDK8 CDK8 CCNQ CCNQ YBX1 YBX1 FURIN FURIN SMAD4 SMAD4 RNF111 RNF111 SERPINE1 SERPINE1 RBL1 RBL1 TGIF2 TGIF2 KXD1 KXD1 MYC MYC MEN1 MEN1 E2F4 E2F4 WWTR1 WWTR1 HDAC1 HDAC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E2F5E2F transcription factor 5. (346 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
LOC100602359Uncharacterized protein. (479 aa)
TFDP1Transcription factor. (395 aa)
CCNKCyclin K; Belongs to the cyclin family. (545 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
EP300E1A binding protein p300. (2306 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (327 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
TGIF1TGFB induced factor homeobox 1. (400 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
ENSNLEP00000025225CYCLIN domain-containing protein; Belongs to the cyclin family. (228 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
SMAD7Mothers against decapentaplegic homolog. (376 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
ENSNLEP00000046336Transcription factor. (371 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
ENSNLEP00000044256CSP domain-containing protein. (264 aa)
ENSNLEP00000044164CYCLIN domain-containing protein; Belongs to the cyclin family. (248 aa)
ENSNLEP00000043660CSP domain-containing protein. (328 aa)
ENSNLEP00000043421Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (393 aa)
ENSNLEP00000043312Homeobox domain-containing protein. (242 aa)
TFDP2Transcription factor. (403 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CCNCCyclin C; Belongs to the cyclin family. (282 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (726 aa)
SP1Sp1 transcription factor. (786 aa)
CDK9Cyclin dependent kinase 9. (372 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
CDK8Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
CCNQCYCLIN domain-containing protein; Belongs to the cyclin family. (248 aa)
YBX1Y-box binding protein 1. (324 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (785 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
RNF111Ring finger protein 111. (995 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
RBL1RB transcriptional corepressor like 1. (1068 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
KXD1KxDL motif containing 1. (195 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
MEN1Menin 1. (614 aa)
E2F4E2F transcription factor 4. (397 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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