STRINGSTRING
PIK3CA PIK3CA KRAS KRAS TREM2 TREM2 PIK3CB PIK3CB FYN FYN LCK LCK VAV3 VAV3 SYK SYK KLRC1 KLRC1 GRB2 GRB2 TYROBP TYROBP NRAS NRAS ENSNLEP00000039370 ENSNLEP00000039370 SPNS3 SPNS3 CSDE1 CSDE1 B2M B2M GRAP2 GRAP2 SPNS1 SPNS1 ENSNLEP00000032399 ENSNLEP00000032399 PIK3R1 PIK3R1 ENSNLEP00000027935 ENSNLEP00000027935 KLRK1 KLRK1 ERAS ERAS SOS1 SOS1 LAT LAT ENSNLEP00000042609 ENSNLEP00000042609 ENSNLEP00000046563 ENSNLEP00000046563 LCP2 LCP2 VAV2 VAV2 RAC1 RAC1 SHC1 SHC1 PLCG2 PLCG2 HRAS HRAS BTK BTK PLCG1 PLCG1 PIK3R2 PIK3R2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
TREM2Ig-like domain-containing protein. (222 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
FYNTyrosine-protein kinase. (537 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
VAV3Vav guanine nucleotide exchange factor 3. (799 aa)
SYKTyrosine-protein kinase. (532 aa)
KLRC1Killer cell lectin like receptor C1. (233 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
TYROBPUncharacterized protein. (144 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
SPNS3Sphingolipid transporter 3 (putative). (460 aa)
CSDE1Cold shock domain containing E1. (844 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
SPNS1Sphingolipid transporter 1 (putative). (476 aa)
ENSNLEP00000032399Uncharacterized protein. (628 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
KLRK1Killer cell lectin like receptor K1. (216 aa)
ERASES cell expressed Ras. (233 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
LATLinker for activation of T cells. (264 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
VAV2Vav guanine nucleotide exchange factor 2. (788 aa)
RAC1Rac family small GTPase 1. (187 aa)
SHC1SHC adaptor protein 1. (542 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
BTKTyrosine-protein kinase. (659 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
PIK3R2Uncharacterized protein. (727 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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