60 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK12	Mitogen-activated protein kinase. (368 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	SLIT2	Slit guidance ligand 2. (1389 aa)
	ENSNLEP00000047852	Laminin N-terminal domain-containing protein. (447 aa)
	NTN4	Netrin 4. (623 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	EZR	Ezrin. (586 aa)
	LOC100584787	Uncharacterized protein. (672 aa)
	ENSNLEP00000043688	Uncharacterized protein. (273 aa)
	ENSNLEP00000042609	Uncharacterized protein. (168 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	CDC42	Cell division cycle 42. (191 aa)
	AGAP1	Uncharacterized protein. (1008 aa)
	DSCAM	DS cell adhesion molecule. (1827 aa)
	PAK1	Non-specific serine/threonine protein kinase. (545 aa)
	ROBO1	Roundabout guidance receptor 1. (1651 aa)
	ENSNLEP00000035864	Uncharacterized protein. (693 aa)
	LOC100605369	Uncharacterized protein. (571 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
	AGAP4	Uncharacterized protein. (684 aa)
	SIAH1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
	UNC5A	Unc-5 netrin receptor A. (932 aa)
	ENSNLEP00000027935	Uncharacterized protein. (181 aa)
	UNC5D	Unc-5 netrin receptor D. (958 aa)
	ENSNLEP00000027584	SH2 domain-containing protein. (188 aa)
	MAPK10	Mitogen-activated protein kinase. (550 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (3026 aa)
	MAPK11	Mitogen-activated protein kinase. (350 aa)
	ENSNLEP00000024736	Uncharacterized protein. (489 aa)
	MAPK14	Mitogen-activated protein kinase. (321 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1186 aa)
	ABLIM1	Actin binding LIM protein 1. (778 aa)
	UNC5B	Unc-5 netrin receptor B. (914 aa)
	RAC1	Rac family small GTPase 1. (187 aa)
	TRPC5	Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
	RGMB	Repulsive guidance molecule BMP co-receptor b. (479 aa)
	NEO1	Neogenin 1. (1461 aa)
	UNC5C	Unc-5 netrin receptor C. (876 aa)
	SLIT1	Slit guidance ligand 1. (1534 aa)
	IGDCC4	Immunoglobulin superfamily DCC subclass member 4. (1258 aa)
	WASL	WASP like actin nucleation promoting factor. (505 aa)
	MYO10	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2031 aa)
	DCC	DCC netrin 1 receptor. (1322 aa)
	ABLIM2	Actin binding LIM protein family member 2. (602 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	ABLIM3	Actin binding LIM protein family member 3. (699 aa)
	TRPC3	Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	TRPC7	Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (864 aa)
	DSCAML1	DS cell adhesion molecule like 1. (1921 aa)
	TRPC6	Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
	HJV	Hemojuvelin BMP co-receptor. (427 aa)
	SLIT3	Slit guidance ligand 3. (1385 aa)
	TRPC1	Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (881 aa)
	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (742 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	SIAH2	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
	TRPC4	Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
	DOCK1	Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABLIM3	CDC42	ENSNLEP00000012361	ENSNLEP00000040816	Actin binding LIM protein family member 3.	Cell division cycle 42.	0.908
AGAP1	UNC5B	ENSNLEP00000040287	ENSNLEP00000019756	Uncharacterized protein.	Unc-5 netrin receptor B.	0.405
AGAP2	UNC5B	ENSNLEP00000020916	ENSNLEP00000019756	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Unc-5 netrin receptor B.	0.913
AGAP3	UNC5B	ENSNLEP00000005181	ENSNLEP00000019756	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3.	Unc-5 netrin receptor B.	0.405
AGAP4	UNC5B	ENSNLEP00000032693	ENSNLEP00000019756	Uncharacterized protein.	Unc-5 netrin receptor B.	0.405
CDC42	ABLIM3	ENSNLEP00000040816	ENSNLEP00000012361	Cell division cycle 42.	Actin binding LIM protein family member 3.	0.908
CDC42	DCC	ENSNLEP00000040816	ENSNLEP00000014442	Cell division cycle 42.	DCC netrin 1 receptor.	0.420
CDC42	DOCK1	ENSNLEP00000040816	ENSNLEP00000000652	Cell division cycle 42.	Dedicator of cytokinesis 1; Belongs to the DOCK family.	0.810
CDC42	ENSNLEP00000027935	ENSNLEP00000040816	ENSNLEP00000027935	Cell division cycle 42.	Uncharacterized protein.	0.583
CDC42	ENSNLEP00000042609	ENSNLEP00000040816	ENSNLEP00000042609	Cell division cycle 42.	Uncharacterized protein.	0.585
CDC42	ENSNLEP00000047852	ENSNLEP00000040816	ENSNLEP00000047852	Cell division cycle 42.	Laminin N-terminal domain-containing protein.	0.596
CDC42	EZR	ENSNLEP00000040816	ENSNLEP00000045659	Cell division cycle 42.	Ezrin.	0.661
CDC42	FYN	ENSNLEP00000040816	ENSNLEP00000041056	Cell division cycle 42.	Tyrosine-protein kinase.	0.972
CDC42	MAPK10	ENSNLEP00000040816	ENSNLEP00000026226	Cell division cycle 42.	Mitogen-activated protein kinase.	0.952
CDC42	MAPK11	ENSNLEP00000040816	ENSNLEP00000025364	Cell division cycle 42.	Mitogen-activated protein kinase.	0.583
CDC42	MAPK12	ENSNLEP00000040816	ENSNLEP00000000724	Cell division cycle 42.	Mitogen-activated protein kinase.	0.962
CDC42	MAPK13	ENSNLEP00000040816	ENSNLEP00000010961	Cell division cycle 42.	Mitogen-activated protein kinase.	0.966
CDC42	MAPK14	ENSNLEP00000040816	ENSNLEP00000024518	Cell division cycle 42.	Mitogen-activated protein kinase.	0.969
CDC42	MAPK8	ENSNLEP00000040816	ENSNLEP00000046032	Cell division cycle 42.	Mitogen-activated protein kinase.	0.976
CDC42	MYO10	ENSNLEP00000040816	ENSNLEP00000014520	Cell division cycle 42.	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.530

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