STRINGSTRING
PTPN11 PTPN11 CD86 CD86 LYN LYN PAK2 PAK2 LCK LCK G1QQJ2_NOMLE G1QQJ2_NOMLE PPP2R5D PPP2R5D CD4 CD4 CD80 CD80 PTPN6 PTPN6 PPP2R5B PPP2R5B FNDC3B FNDC3B PIK3CA PIK3CA PIK3R2 PIK3R2 HLA-DRA HLA-DRA HLA-DQA2 HLA-DQA2 HLA-DPB1 HLA-DPB1 YES1 YES1 PPP4R1 PPP4R1 CD28 CD28 CTLA4 CTLA4 ICOS ICOS CD3D CD3D CD3G CD3G PDCD1 PDCD1 RELCH RELCH CD274 CD274 PDCD1LG2 PDCD1LG2 LOC100592336 LOC100592336 TRIB3 TRIB3 THEM4 THEM4 PPP2CB PPP2CB PPP2R5E PPP2R5E CD276 CD276 CSK CSK CD247 CD247 RAC1 RAC1 RICTOR RICTOR MAP3K8 MAP3K8 PPP4R4 PPP4R4 AKT3 AKT3 ENSNLEP00000024590 ENSNLEP00000024590 ENSNLEP00000024736 ENSNLEP00000024736 PPP2R5C PPP2R5C VAV1 VAV1 ENSNLEP00000027584 ENSNLEP00000027584 ENSNLEP00000027935 ENSNLEP00000027935 AKT1 AKT1 HLA-DPA1 HLA-DPA1 PIK3R1 PIK3R1 MAP3K14 MAP3K14 PPP2R1B PPP2R1B ENSNLEP00000032399 ENSNLEP00000032399 MTOR MTOR LOC100605369 LOC100605369 PPP2R5A PPP2R5A GRAP2 GRAP2 PPP2R1A PPP2R1A MLST8 MLST8 PAK3 PAK3 FNDC3A FNDC3A PAK1 PAK1 FNBP4 FNBP4 PRR5 PRR5 TNFRSF14 TNFRSF14 LOC100593010 LOC100593010 GRB2 GRB2 CDC42 CDC42 ENSNLEP00000040897 ENSNLEP00000040897 FYN FYN ENSNLEP00000041365 ENSNLEP00000041365 PPP2CA PPP2CA CD3E CD3E AKT2 AKT2 ENSNLEP00000042609 ENSNLEP00000042609 ICOSLG ICOSLG ENSNLEP00000043688 ENSNLEP00000043688 HLA-DQB2 HLA-DQB2 HLA-DQB1 HLA-DQB1 ENSNLEP00000045105 ENSNLEP00000045105 PIK3R3 PIK3R3 ENSNLEP00000045775 ENSNLEP00000045775 BTLA BTLA MAPKAP1 MAPKAP1 SRC SRC ENSNLEP00000048582 ENSNLEP00000048582 ENSNLEP00000048970 ENSNLEP00000048970
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
CD86CD86 molecule. (329 aa)
LYNTyrosine-protein kinase. (512 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
G1QQJ2_NOMLEIg-like domain-containing protein. (128 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (607 aa)
CD4CD4 molecule. (458 aa)
CD80CD80 molecule. (288 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (627 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (424 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
PIK3R2Uncharacterized protein. (727 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
HLA-DQA2Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
YES1Tyrosine-protein kinase. (519 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (950 aa)
CD28CD28 molecule. (220 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
ICOSInducible T cell costimulator. (199 aa)
CD3DCD3d molecule. (153 aa)
CD3GCD3g molecule. (182 aa)
PDCD1Programmed cell death 1. (288 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1219 aa)
CD274CD274 molecule. (290 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
THEM4Thioesterase superfamily member 4. (240 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa)
CD276Uncharacterized protein. (299 aa)
CSKTyrosine-protein kinase. (274 aa)
CD247CD247 molecule. (163 aa)
RAC1Rac family small GTPase 1. (187 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1709 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (855 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSNLEP00000024590Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (479 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
VAV1Uncharacterized protein. (739 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (939 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (666 aa)
ENSNLEP00000032399Uncharacterized protein. (628 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
LOC100605369Uncharacterized protein. (571 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (588 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
FNBP4Formin binding protein 4. (1022 aa)
PRR5Proline rich 5. (410 aa)
TNFRSF14TNFR-Cys domain-containing protein. (231 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CDC42Cell division cycle 42. (191 aa)
ENSNLEP00000040897Uncharacterized protein. (331 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSNLEP00000041365Ig-like domain-containing protein. (298 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CD3ECD3e molecule. (198 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
ICOSLGUncharacterized protein. (411 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
HLA-DQB2Major histocompatibility complex, class II, DQ beta 2. (264 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
ENSNLEP00000045105Ig-like domain-containing protein. (175 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
ENSNLEP00000045775Uncharacterized protein. (113 aa)
BTLAB and T lymphocyte associated. (289 aa)
MAPKAP1MAPK associated protein 1. (523 aa)
SRCTyrosine-protein kinase. (537 aa)
ENSNLEP00000048582DUF1968 domain-containing protein. (204 aa)
ENSNLEP00000048970Ig-like domain-containing protein. (142 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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