42 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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protein homology

Your Input:
	LYN	Tyrosine-protein kinase. (512 aa)
	CD86	CD86 molecule. (329 aa)
	YES1	Tyrosine-protein kinase. (519 aa)
	THEM4	Thioesterase superfamily member 4. (240 aa)
	CD276	Uncharacterized protein. (299 aa)
	RAC1	Rac family small GTPase 1. (187 aa)
	RICTOR	RPTOR independent companion of MTOR complex 2. (1709 aa)
	MAP3K8	Mitogen-activated protein kinase kinase kinase 8. (467 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	VAV1	Uncharacterized protein. (739 aa)
	ENSNLEP00000027935	Uncharacterized protein. (181 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
	CD28	CD28 molecule. (220 aa)
	PAK3	P21 (RAC1) activated kinase 3. (580 aa)
	MLST8	MTOR associated protein, LST8 homolog. (326 aa)
	GRAP2	GRB2 related adaptor protein 2. (330 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (939 aa)
	LOC100592336	PH_3 domain-containing protein. (247 aa)
	TRIB3	Tribbles pseudokinase 3. (385 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	ENSNLEP00000032399	Uncharacterized protein. (628 aa)
	ENSNLEP00000040897	Uncharacterized protein. (331 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1204 aa)
	CD80	CD80 molecule. (288 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	MAPKAP1	MAPK associated protein 1. (523 aa)
	ENSNLEP00000045775	Uncharacterized protein. (113 aa)
	LCK	LCK proto-oncogene, Src family tyrosine kinase. (448 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
	ENSNLEP00000042609	Uncharacterized protein. (168 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	PAK1	Non-specific serine/threonine protein kinase. (545 aa)
	PRR5	Proline rich 5. (410 aa)
	LOC100593010	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	CDC42	Cell division cycle 42. (191 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSNLEP00000028045	ENSNLEP00000042041	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.891
AKT1	AKT3	ENSNLEP00000028045	ENSNLEP00000023896	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.950
AKT1	CD28	ENSNLEP00000028045	ENSNLEP00000008599	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD28 molecule.	0.641
AKT1	CD80	ENSNLEP00000028045	ENSNLEP00000006009	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD80 molecule.	0.605
AKT1	CD86	ENSNLEP00000028045	ENSNLEP00000000328	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD86 molecule.	0.621
AKT1	CDC42	ENSNLEP00000028045	ENSNLEP00000040816	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cell division cycle 42.	0.961
AKT1	ENSNLEP00000027935	ENSNLEP00000028045	ENSNLEP00000027935	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.494
AKT1	ENSNLEP00000032399	ENSNLEP00000028045	ENSNLEP00000032399	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.514
AKT1	ENSNLEP00000042609	ENSNLEP00000028045	ENSNLEP00000042609	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.494
AKT1	ENSNLEP00000045775	ENSNLEP00000028045	ENSNLEP00000045775	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.628
AKT1	FYN	ENSNLEP00000028045	ENSNLEP00000041056	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.706
AKT1	GRB2	ENSNLEP00000028045	ENSNLEP00000040743	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor bound protein 2.	0.749
AKT1	LCK	ENSNLEP00000028045	ENSNLEP00000002978	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	LCK proto-oncogene, Src family tyrosine kinase.	0.741
AKT1	LOC100592336	ENSNLEP00000028045	ENSNLEP00000011475	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	PH_3 domain-containing protein.	0.982
AKT1	LOC100593010	ENSNLEP00000028045	ENSNLEP00000040615	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.985
AKT1	LYN	ENSNLEP00000028045	ENSNLEP00000001435	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.703
AKT1	MAP3K14	ENSNLEP00000028045	ENSNLEP00000031961	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 14.	0.446
AKT1	MAP3K8	ENSNLEP00000028045	ENSNLEP00000020726	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 8.	0.954
AKT1	MAPKAP1	ENSNLEP00000028045	ENSNLEP00000047528	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK associated protein 1.	0.937
AKT1	MLST8	ENSNLEP00000028045	ENSNLEP00000036779	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MTOR associated protein, LST8 homolog.	0.837

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