STRINGSTRING
SRC SRC ENSNLEP00000035684 ENSNLEP00000035684 LIMK1 LIMK1 ENSNLEP00000036737 ENSNLEP00000036737 GRIN1 GRIN1 ACTB ACTB ENSNLEP00000038443 ENSNLEP00000038443 ROCK2 ROCK2 ENSNLEP00000035534 ENSNLEP00000035534 FMN1 FMN1 ENSNLEP00000034648 ENSNLEP00000034648 PTK2 PTK2 ENSNLEP00000033007 ENSNLEP00000033007 ENSNLEP00000032002 ENSNLEP00000032002 ENSNLEP00000030621 ENSNLEP00000030621 DSTN DSTN ENSNLEP00000024646 ENSNLEP00000024646 FNDC3A FNDC3A PAK1 PAK1 CDC42 CDC42 FYN FYN ENSNLEP00000041102 ENSNLEP00000041102 EFNB2 EFNB2 EPHB2 EPHB2 ENSNLEP00000042609 ENSNLEP00000042609 ROCK1 ROCK1 LIMK2 LIMK2 ARPC2 ARPC2 ACTRT2 ACTRT2 ARPC4 ARPC4 LOC100593698 LOC100593698 ENSNLEP00000048240 ENSNLEP00000048240 ITSN1 ITSN1 ACTG1 ACTG1 ACTL9 ACTL9 SDC2 SDC2 ACTR2 ACTR2 ENSNLEP00000027935 ENSNLEP00000027935 ENSNLEP00000026528 ENSNLEP00000026528 CFL1 CFL1 ACTL7A ACTL7A ACTL7B ACTL7B ARPC5 ARPC5 ARPC5L ARPC5L RAC1 RAC1 ACTR3B ACTR3B RASA1 RASA1 WASL WASL EPHB4 EPHB4 ACTR3 ACTR3 ARPC1B ARPC1B ARPC1A ARPC1A EFNB3 EFNB3 HRAS HRAS ACTL8 ACTL8 YES1 YES1 RHOA RHOA EPHB3 EPHB3 FNDC3B FNDC3B ARHGEF28 ARHGEF28 EPHB1 EPHB1 GRIN2B GRIN2B FMN2 FMN2 TIAM1 TIAM1 CFL2 CFL2 ARPC3 ARPC3 EPHB6 EPHB6 LYN LYN EFNB1 EFNB1 KALRN KALRN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRCTyrosine-protein kinase. (537 aa)
ENSNLEP00000035684WD_REPEATS_REGION domain-containing protein. (199 aa)
LIMK1Uncharacterized protein. (614 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (888 aa)
ACTBUncharacterized protein. (363 aa)
ENSNLEP00000038443Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (154 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
ENSNLEP00000035534ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (189 aa)
FMN1Formin 1. (1424 aa)
ENSNLEP00000034648ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (210 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
ENSNLEP00000033007Uncharacterized protein; Belongs to the actin family. (312 aa)
ENSNLEP00000032002ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (116 aa)
ENSNLEP00000030621WD_REPEATS_REGION domain-containing protein. (322 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
ENSNLEP00000024646Uncharacterized protein. (137 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
CDC42Cell division cycle 42. (191 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSNLEP00000041102ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (151 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (299 aa)
EPHB2EPH receptor B2. (1015 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
LIMK2LIM domain kinase 2. (638 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (275 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (369 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (187 aa)
LOC100593698Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (172 aa)
ENSNLEP00000048240ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (164 aa)
ITSN1Intersectin 1. (1675 aa)
ACTG1Actin gamma 1. (378 aa)
ACTL9Actin like 9; Belongs to the actin family. (416 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
ENSNLEP00000026528Uncharacterized protein. (337 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (197 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
RAC1Rac family small GTPase 1. (187 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (303 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
EPHB4EPH receptor B4. (890 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (417 aa)
ARPC1BWD_REPEATS_REGION domain-containing protein. (598 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
EFNB3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (287 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
YES1Tyrosine-protein kinase. (519 aa)
RHOARas homolog family member A. (193 aa)
EPHB3EPH receptor B3. (1053 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1731 aa)
EPHB1EPH receptor B1. (984 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1335 aa)
FMN2Formin 2. (1613 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1561 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (163 aa)
EPHB6EPH receptor B6. (1019 aa)
LYNTyrosine-protein kinase. (512 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
KALRNUncharacterized protein. (2931 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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