STRINGSTRING
MMP2 MMP2 LYN LYN SRC SRC VAV2 VAV2 ACTRT2 ACTRT2 ENSNLEP00000042609 ENSNLEP00000042609 EPHA4 EPHA4 EFNA4 EFNA4 EPHB2 EPHB2 EFNB2 EFNB2 FYN FYN EPHA7 EPHA7 FNDC3A FNDC3A EFNA2 EFNA2 DNM1 DNM1 ACTB ACTB PSENEN PSENEN CLTA CLTA ENSNLEP00000033007 ENSNLEP00000033007 ENSNLEP00000031226 ENSNLEP00000031226 PSEN1 PSEN1 ENSNLEP00000030293 ENSNLEP00000030293 EPHA8 EPHA8 AP2B1 AP2B1 ENSNLEP00000027935 ENSNLEP00000027935 ENSNLEP00000026528 ENSNLEP00000026528 EFNA1 EFNA1 ADAM10 ADAM10 AP2S1 AP2S1 EFNA3 EFNA3 ACTG1 ACTG1 ACTL9 ACTL9 ACTL7A ACTL7A ACTL7B ACTL7B RAC1 RAC1 PSEN2 PSEN2 NCSTN NCSTN CLTB CLTB APH1B APH1B EPHB4 EPHB4 EPHA3 EPHA3 EPHA10 EPHA10 EFNA5 EFNA5 APH1A APH1A EFNB3 EFNB3 EPHA5 EPHA5 AP2A2 AP2A2 EPHA2 EPHA2 MMP9 MMP9 YES1 YES1 EPHB3 EPHB3 AP2M1 AP2M1 FNDC3B FNDC3B AP2A1 AP2A1 CLTCL1 CLTCL1 EPHB1 EPHB1 EFNB1 EFNB1 CLTC CLTC TIAM1 TIAM1 EPHA1 EPHA1 EPHB6 EPHB6 EPHA6 EPHA6 VAV3 VAV3 LOC100588056 LOC100588056
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP2Matrix metallopeptidase 2. (647 aa)
LYNTyrosine-protein kinase. (512 aa)
SRCTyrosine-protein kinase. (537 aa)
VAV2Vav guanine nucleotide exchange factor 2. (788 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (369 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
EPHA4EPH receptor A4. (967 aa)
EFNA4Ephrin RBD domain-containing protein; Belongs to the ephrin family. (201 aa)
EPHB2EPH receptor B2. (1015 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (299 aa)
FYNTyrosine-protein kinase. (537 aa)
EPHA7EPH receptor A7. (972 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
EFNA2Ephrin RBD domain-containing protein; Belongs to the ephrin family. (195 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (827 aa)
ACTBUncharacterized protein. (363 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
ENSNLEP00000033007Uncharacterized protein; Belongs to the actin family. (312 aa)
ENSNLEP00000031226AP complex subunit beta. (907 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ENSNLEP00000030293Uncharacterized protein. (912 aa)
EPHA8EPH receptor A8. (987 aa)
AP2B1AP complex subunit beta. (951 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
ENSNLEP00000026528Uncharacterized protein. (337 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (204 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
EFNA3Ephrin A3; Belongs to the ephrin family. (238 aa)
ACTG1Actin gamma 1. (378 aa)
ACTL9Actin like 9; Belongs to the actin family. (416 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
RAC1Rac family small GTPase 1. (187 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
NCSTNNicastrin. (702 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (186 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
EPHB4EPH receptor B4. (890 aa)
EPHA3EPH receptor A3. (983 aa)
EPHA10EPH receptor A10. (1080 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
EFNB3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (287 aa)
EPHA5EPH receptor A5. (1038 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (923 aa)
EPHA2EPH receptor A2. (976 aa)
MMP9Matrix metallopeptidase 9. (692 aa)
YES1Tyrosine-protein kinase. (519 aa)
EPHB3EPH receptor B3. (1053 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (906 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1638 aa)
EPHB1EPH receptor B1. (984 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1561 aa)
EPHA1EPH receptor A1. (975 aa)
EPHB6EPH receptor B6. (1019 aa)
EPHA6EPH receptor A6. (1130 aa)
VAV3Vav guanine nucleotide exchange factor 3. (799 aa)
LOC100588056Fibronectin type-II domain-containing protein. (75 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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