STRINGSTRING
AP2S1 AP2S1 CACNG3 CACNG3 AP2A2 AP2A2 TMEM35A TMEM35A TSPAN6 TSPAN6 GRIA4 GRIA4 GRIA2 GRIA2 CACNG8 CACNG8 PRKCG PRKCG AP2M1 AP2M1 AP2A1 AP2A1 GRIP2 GRIP2 NSF NSF CAMK2B CAMK2B PRKCA PRKCA DLG4 DLG4 ENSNLEP00000030293 ENSNLEP00000030293 GRIP1 GRIP1 DLG1 DLG1 AP2B1 AP2B1 LOC105738539 LOC105738539 CACNG4 CACNG4 TSPAN7 TSPAN7 CAMK2D CAMK2D CAMK2A CAMK2A PRKCB PRKCB ENSNLEP00000031226 ENSNLEP00000031226 MYO6 MYO6 CACNG2 CACNG2 PICK1 PICK1 GRIA3 GRIA3 CAMK2G CAMK2G AKAP5 AKAP5 GRIA1 GRIA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (923 aa)
TMEM35ATransmembrane protein 35A. (167 aa)
TSPAN6Tetraspanin. (245 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (424 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (906 aa)
GRIP2Glutamate receptor interacting protein 2. (1142 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (748 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (607 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (746 aa)
ENSNLEP00000030293Uncharacterized protein. (912 aa)
GRIP1Glutamate receptor interacting protein 1. (1128 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa)
AP2B1AP complex subunit beta. (951 aa)
LOC105738539Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (134 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
TSPAN7Tetraspanin. (266 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ENSNLEP00000031226AP complex subunit beta. (907 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
PICK1Protein interacting with PRKCA 1. (415 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (900 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (524 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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