STRINGSTRING
ENSNLEP00000028868 ENSNLEP00000028868 PRKACB PRKACB CACNA1A CACNA1A GNB3 GNB3 ADCY6 ADCY6 GNG2 GNG2 GNB5 GNB5 PRKAR2A PRKAR2A FAP FAP PRKAR2B PRKAR2B STX1A STX1A ITPR2 ITPR2 ENSNLEP00000036455 ENSNLEP00000036455 PRKACG PRKACG ADCY8 ADCY8 CACNA2D2 CACNA2D2 GNG12 GNG12 GNG7 GNG7 ITPR3 ITPR3 ABCC8 ABCC8 PRKAR1A PRKAR1A SYT5 SYT5 CACNB2 CACNB2 KCNC2 KCNC2 KCNJ11 KCNJ11 CACNA1D CACNA1D CD36 CD36 MARCKS MARCKS ENSNLEP00000046477 ENSNLEP00000046477 GNA15 GNA15 ENSNLEP00000047903 ENSNLEP00000047903 ADCY5 ADCY5 THAP6 THAP6 THAP7 THAP7 GNB1 GNB1 PRKCA PRKCA RAPGEFL1 RAPGEFL1 KCNS3 KCNS3 GNA11 GNA11 GCG GCG CACNA1C CACNA1C GNG8 GNG8 PLCB2 PLCB2 GNA14 GNA14 GNAQ GNAQ GNGT2 GNGT2 AHCYL1 AHCYL1 ITPR1 ITPR1 RAP1A RAP1A GNG3 GNG3 PLCB3 PLCB3 SLC2A2 SLC2A2 RAPGEF4 RAPGEF4 GNB4 GNB4 GNAI2 GNAI2 KCNB1 KCNB1 CACNA1F CACNA1F PRKAR1B PRKAR1B GNAS GNAS GNAI1 GNAI1 ACSL3 ACSL3 VAMP2 VAMP2 GNG5 GNG5 GLP1R GLP1R GNB2 GNB2 IQGAP1 IQGAP1 SLC2A1 SLC2A1 PLCB1 PLCB1 ACSL4 ACSL4 SNAP25 SNAP25 CACNA2D1 CACNA2D1 G1RZK2_NOMLE G1RZK2_NOMLE GNGT1 GNGT1 GNG11 GNG11 RAPGEF5 RAPGEF5 STXBP1 STXBP1 CACNB3 CACNB3 RAPGEF3 RAPGEF3 CACNA1E CACNA1E CHRM3 CHRM3 ADRA2C ADRA2C AKAP5 AKAP5 PRKACA PRKACA GNG13 GNG13 GNG4 GNG4 LOC100586578 LOC100586578
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSNLEP00000028868G protein gamma domain-containing protein. (64 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2399 aa)
GNB3G protein subunit beta 3. (335 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
GNB5G protein subunit beta 5. (357 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (343 aa)
STX1At-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (243 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
ENSNLEP00000036455Uncharacterized protein. (127 aa)
PRKACGUncharacterized protein. (290 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1119 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2755 aa)
ABCC8ATP binding cassette subfamily C member 8. (1569 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
SYT5C2 domain-containing protein. (235 aa)
CACNB2GuKc domain-containing protein. (586 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2116 aa)
CD36CD36 molecule; Belongs to the CD36 family. (433 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (328 aa)
ENSNLEP00000046477Uncharacterized protein. (273 aa)
GNA15G protein subunit alpha 15. (322 aa)
ENSNLEP00000047903Uncharacterized protein. (340 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
THAP6THAP domain containing 6. (222 aa)
THAP7THAP domain containing 7. (304 aa)
GNB1G protein subunit beta 1. (340 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
RAPGEFL1Ras-GEF domain-containing protein. (374 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
GNA11Uncharacterized protein. (217 aa)
GCGGlucagon. (180 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1985 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1083 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNAQG protein subunit alpha q. (358 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (529 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (925 aa)
GNB4G protein subunit beta 4. (340 aa)
GNAI2G protein subunit alpha i2. (355 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1967 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (320 aa)
GNASGNAS complex locus. (1038 aa)
GNAI1G protein subunit alpha i1. (353 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
GNB2G protein subunit beta 2. (325 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (462 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1071 aa)
G1RZK2_NOMLECyclic nucleotide-binding domain-containing protein. (82 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (604 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (444 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (853 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2230 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
ADRA2CG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
PRKACAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (116 aa)
LOC100586578Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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