70 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACTL7A	Actin like 7A; Belongs to the actin family. (435 aa)
	MSN	Moesin. (566 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
	KIF4A	Kinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1212 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (738 aa)
	NUMB	NUMB endocytic adaptor protein. (650 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (906 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1204 aa)
	VSIG10L	V-set and immunoglobulin domain containing 10 like. (863 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa)
	RDX	Radixin. (604 aa)
	ACTL8	Actin like 8; Belongs to the actin family. (366 aa)
	TUBA8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (923 aa)
	TUBB6	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (418 aa)
	LOC100592418	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (430 aa)
	CLHC1	Clathrin heavy chain linker domain-containing protein 1. (586 aa)
	LOC100600563	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	TUBA4A	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	TUBB1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (732 aa)
	TUBA3E	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
	LOC100585215	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	TUBB2B	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	TUBAL3	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
	RPS6KA2	Non-specific serine/threonine protein kinase. (692 aa)
	L1CAM	L1 cell adhesion molecule. (1174 aa)
	DNM3	Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
	LOC100594805	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	DPYSL2	Dihydropyrimidinase like 2. (572 aa)
	SHTN1	Shootin 1. (631 aa)
	KIF4B	Kinesin family member 4B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1171 aa)
	TUBA1C	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (518 aa)
	LOC100585634	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (351 aa)
	ACTL7B	Actin like 7B; Belongs to the actin family. (415 aa)
	ACTL9	Actin like 9; Belongs to the actin family. (416 aa)
	ACTG1	Actin gamma 1. (378 aa)
	LOC100587604	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	HMCN1	Hemicentin 1. (5494 aa)
	TUBB8	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (376 aa)
	ENSNLEP00000026528	Uncharacterized protein. (337 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
	RPS6KA5	Ribosomal protein S6 kinase. (797 aa)
	AP2B1	AP complex subunit beta. (951 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (770 aa)
	TUBB2A	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	ENSNLEP00000030293	Uncharacterized protein. (912 aa)
	VSIG10L2	V-set and immunoglobulin domain containing 10 like 2. (767 aa)
	ENSNLEP00000031226	AP complex subunit beta. (907 aa)
	LOC100604350	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
	ENSNLEP00000032432	Tubulin domain-containing protein. (95 aa)
	ENSNLEP00000033007	Uncharacterized protein; Belongs to the actin family. (312 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
	RPS6KA4	Ribosomal protein S6 kinase. (743 aa)
	ENSNLEP00000036252	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa)
	TUBB4B	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (428 aa)
	ACTB	Uncharacterized protein. (363 aa)
	DNM1	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (827 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	ENSNLEP00000039881	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (387 aa)
	HMCN2	Hemicentin 2. (4924 aa)
	LOC100580376	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	TUBA4B	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (237 aa)
	ACTRT2	Actin related protein T2; Belongs to the actin family. (369 aa)
	TUBB4A	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (372 aa)
	EZR	Ezrin. (586 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
	SRC	Tyrosine-protein kinase. (537 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTG1	ENSNLEP00000038010	ENSNLEP00000023255	Uncharacterized protein.	Actin gamma 1.	0.888
ACTB	CLTC	ENSNLEP00000038010	ENSNLEP00000001008	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.455
ACTB	ENSNLEP00000036252	ENSNLEP00000038010	ENSNLEP00000036252	Uncharacterized protein.	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.455
ACTB	EZR	ENSNLEP00000038010	ENSNLEP00000045659	Uncharacterized protein.	Ezrin.	0.521
ACTB	LOC100585215	ENSNLEP00000038010	ENSNLEP00000012834	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.461
ACTB	LOC100585634	ENSNLEP00000038010	ENSNLEP00000021664	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.483
ACTB	LOC100587604	ENSNLEP00000038010	ENSNLEP00000024125	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.461
ACTB	LOC100604350	ENSNLEP00000038010	ENSNLEP00000032122	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.480
ACTB	MAPK1	ENSNLEP00000038010	ENSNLEP00000027273	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.505
ACTB	MSN	ENSNLEP00000038010	ENSNLEP00000000536	Uncharacterized protein.	Moesin.	0.473
ACTB	SRC	ENSNLEP00000038010	ENSNLEP00000048569	Uncharacterized protein.	Tyrosine-protein kinase.	0.537
ACTB	TUBA1C	ENSNLEP00000038010	ENSNLEP00000021663	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.593
ACTB	TUBA3E	ENSNLEP00000038010	ENSNLEP00000012638	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.462
ACTB	TUBA4A	ENSNLEP00000038010	ENSNLEP00000011349	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.633
ACTB	TUBA4B	ENSNLEP00000038010	ENSNLEP00000044521	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.500
ACTB	TUBA8	ENSNLEP00000038010	ENSNLEP00000009611	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.520
ACTB	TUBAL3	ENSNLEP00000038010	ENSNLEP00000013810	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.541
ACTB	TUBB2A	ENSNLEP00000038010	ENSNLEP00000029354	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.566
ACTB	TUBB4A	ENSNLEP00000038010	ENSNLEP00000045484	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.520
ACTB	TUBB6	ENSNLEP00000038010	ENSNLEP00000010911	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.460

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