STRINGSTRING
THEM4 THEM4 JUP JUP STX7 STX7 RAC1 RAC1 RICTOR RICTOR AKT3 AKT3 HSP90AA1 HSP90AA1 VAV1 VAV1 STX12 STX12 ENSNLEP00000027935 ENSNLEP00000027935 AKT1 AKT1 CAV1 CAV1 CTNNA1 CTNNA1 MTOR MTOR MLST8 MLST8 PAK3 PAK3 PAK1 PAK1 VAV3 VAV3 PRR5 PRR5 ENSNLEP00000040381 ENSNLEP00000040381 LOC100593010 LOC100593010 CTNND1 CTNND1 AKT2 AKT2 ENSNLEP00000042609 ENSNLEP00000042609 ENSNLEP00000045775 ENSNLEP00000045775 MAPKAP1 MAPKAP1 VAV2 VAV2 PAK2 PAK2 CDH5 CDH5 NOS3 NOS3 ARVCF ARVCF CTNNB1 CTNNB1 LOC100592336 LOC100592336 TRIB3 TRIB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THEM4Thioesterase superfamily member 4. (240 aa)
JUPJunction plakoglobin. (730 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
RAC1Rac family small GTPase 1. (187 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1709 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (853 aa)
VAV1Uncharacterized protein. (739 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
CTNNA1Catenin alpha 1. (895 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
VAV3Vav guanine nucleotide exchange factor 3. (799 aa)
PRR5Proline rich 5. (410 aa)
ENSNLEP00000040381Uncharacterized protein. (760 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
CTNND1Catenin delta 1. (968 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
ENSNLEP00000045775Uncharacterized protein. (113 aa)
MAPKAP1MAPK associated protein 1. (523 aa)
VAV2Vav guanine nucleotide exchange factor 2. (788 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (687 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
ARVCFARVCF delta catenin family member. (918 aa)
CTNNB1Catenin beta 1. (781 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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