STRINGSTRING
BIRC3 BIRC3 UBE2D3 UBE2D3 TNF TNF BIRC8 BIRC8 ENSNLEP00000046839 ENSNLEP00000046839 RACK1 RACK1 ENSNLEP00000046237 ENSNLEP00000046237 MIB2 MIB2 RPS27A RPS27A OTUD1 OTUD1 NFATC4 NFATC4 CASP8 CASP8 ENSNLEP00000039422 ENSNLEP00000039422 ENSNLEP00000038869 ENSNLEP00000038869 OPTN OPTN ENSNLEP00000038579 ENSNLEP00000038579 BIRC2 BIRC2 ENSNLEP00000037583 ENSNLEP00000037583 ULK2 ULK2 ENSNLEP00000034619 ENSNLEP00000034619 ENSNLEP00000033776 ENSNLEP00000033776 CYLD CYLD UBE2D2 UBE2D2 LOC100589118 LOC100589118 TNFRSF1A TNFRSF1A ENSNLEP00000028940 ENSNLEP00000028940 ENSNLEP00000027887 ENSNLEP00000027887 ENSNLEP00000026722 ENSNLEP00000026722 SPATA2 SPATA2 LOC100591412 LOC100591412 CHUK CHUK TAX1BP1 TAX1BP1 RPS27A-2 RPS27A-2 UBE2L5 UBE2L5 G1SAA8_NOMLE G1SAA8_NOMLE TRAF1 TRAF1 TBK1 TBK1 WDR31 WDR31 CLIP4 CLIP4 RNF31 RNF31 XIAP XIAP TNFAIP3 TNFAIP3 MADD MADD IKBKG IKBKG USP21 USP21 IKBKB IKBKB UBE2D1 UBE2D1 OTULIN OTULIN OTULINL OTULINL LOC100606443 LOC100606443 CLIP3 CLIP3 RIPK1 RIPK1 SHARPIN SHARPIN FADD FADD BIRC7 BIRC7 OTUD7B OTUD7B TMEM198 TMEM198 RBCK1 RBCK1 TRAF2 TRAF2 ULK1 ULK1 STUB1 STUB1 USP2 USP2 CFLAR CFLAR USP4 USP4 SPPL2A SPPL2A KXD1 KXD1 NAIP NAIP TRADD TRADD MAPKAPK2 MAPKAPK2 IKBKE IKBKE LOC100598782 LOC100598782
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BIRC3Baculoviral IAP repeat containing 3. (603 aa)
UBE2D3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
BIRC8Uncharacterized protein. (221 aa)
ENSNLEP00000046839DUF4203 domain-containing protein. (93 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (320 aa)
ENSNLEP00000046237UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (136 aa)
MIB2Uncharacterized protein. (929 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
OTUD1OTU domain-containing protein. (492 aa)
NFATC4Nuclear factor of activated T cells 4. (844 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
OPTNOptineurin. (577 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
BIRC2Baculoviral IAP repeat containing 2. (615 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1023 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
ENSNLEP00000033776UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC100589118Uncharacterized protein. (84 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ENSNLEP00000028940UBIQUITIN_CONJUGAT_2 domain-containing protein. (110 aa)
ENSNLEP00000027887DUF4203 domain-containing protein. (101 aa)
ENSNLEP00000026722UBIQUITIN_CONJUGAT_2 domain-containing protein. (128 aa)
SPATA2Spermatogenesis associated 2. (519 aa)
LOC100591412UBIQUITIN_CONJUGAT_2 domain-containing protein. (134 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
TAX1BP1Tax1 binding protein 1. (813 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
UBE2L5Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
G1SAA8_NOMLEUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
TRAF1TNF receptor-associated factor. (416 aa)
TBK1TANK binding kinase 1. (729 aa)
WDR31WD repeat domain 31. (367 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (689 aa)
RNF31Uncharacterized protein. (1072 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
MADDMAP kinase activating death domain. (1459 aa)
IKBKGNEMO domain-containing protein. (173 aa)
USP21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (566 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (345 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (357 aa)
LOC100606443Uncharacterized protein. (476 aa)
CLIP3CAP-Gly domain containing linker protein 3. (504 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
SHARPINSHANK associated RH domain interactor. (340 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
OTUD7BOTU deubiquitinase 7B. (849 aa)
TMEM198Transmembrane protein 198. (360 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (509 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
STUB1Uncharacterized protein. (231 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (577 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
SPPL2ASignal peptide peptidase like 2A. (520 aa)
KXD1KxDL motif containing 1. (195 aa)
NAIPNLR family apoptosis inhibitory protein. (1257 aa)
TRADDTNFRSF1A associated via death domain. (311 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (676 aa)
LOC100598782UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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