STRINGSTRING
MAP3K14 MAP3K14 ENSNLEP00000031906 ENSNLEP00000031906 PSMD10 PSMD10 PPP3CA PPP3CA ENSNLEP00000029825 ENSNLEP00000029825 SYK SYK PSMB3 PSMB3 PSMD9 PSMD9 PSMD3 PSMD3 RELB RELB UBA3 UBA3 PSMA2 PSMA2 AHCYL1 AHCYL1 CUL1 CUL1 ITPR1 ITPR1 NFKBIA NFKBIA PSMC5 PSMC5 PSMB10 PSMB10 NFAT5 NFAT5 UBE2N UBE2N PSMD11 PSMD11 KXD1 KXD1 PSMA8 PSMA8 PSMB8 PSMB8 PSMB9 PSMB9 PRKCD PRKCD SKP1 SKP1 CARD9 CARD9 MALT1 MALT1 PSMC2 PSMC2 LOC100592336 LOC100592336 PSMD4 PSMD4 PSMB4 PSMB4 CARD11 CARD11 PLCG2 PLCG2 UBE2M UBE2M PSMC6 PSMC6 IKBKB IKBKB PSMA3 PSMA3 NFKB1 NFKB1 MAP3K7 MAP3K7 PSMC4 PSMC4 IKBKG IKBKG PSMC3 PSMC3 BTRC BTRC NFKB2 NFKB2 TAB1 TAB1 TAB2 TAB2 PSMA7 PSMA7 PYCARD PYCARD PSMD8 PSMD8 PSMC1 PSMC1 PSMD5 PSMD5 TRAF6 TRAF6 RPS27A-2 RPS27A-2 PSMA1 PSMA1 MAP3K20 MAP3K20 ENSNLEP00000049245 ENSNLEP00000049245 ENSNLEP00000049227 ENSNLEP00000049227 SRC SRC ENSNLEP00000048393 ENSNLEP00000048393 LOC100606243 LOC100606243 PSMD13 PSMD13 PSMB7 PSMB7 ENSNLEP00000046239 ENSNLEP00000046239 NFATC3 NFATC3 PSMD6 PSMD6 IL1B IL1B TAB3 TAB3 PSME4 PSME4 RPS27A RPS27A PSMB2 PSMB2 PSMD2 PSMD2 CHUK CHUK ENSNLEP00000026115 ENSNLEP00000026115 PPP3R1 PPP3R1 CCDC71L CCDC71L LOC100591996 LOC100591996 PPP3CB PPP3CB ENSNLEP00000027432 ENSNLEP00000027432 PSMD12 PSMD12 PSMA5 PSMA5 PSMA6 PSMA6 PSMA4 PSMA4 ENSNLEP00000029611 ENSNLEP00000029611 FBXW11 FBXW11 ENSNLEP00000042742 ENSNLEP00000042742 WDR92 WDR92 ENSNLEP00000042252 ENSNLEP00000042252 ENSNLEP00000042204 ENSNLEP00000042204 ENSNLEP00000041707 ENSNLEP00000041707 PSMD1 PSMD1 ENSNLEP00000041226 ENSNLEP00000041226 PSMB5 PSMB5 BCL10 BCL10 LOC100593010 LOC100593010 CASP8 CASP8 ENSNLEP00000040208 ENSNLEP00000040208 ITPR3 ITPR3 NFATC1 NFATC1 PSME3 PSME3 ENSNLEP00000039422 ENSNLEP00000039422 ENSNLEP00000039192 ENSNLEP00000039192 ENSNLEP00000039157 ENSNLEP00000039157 ENSNLEP00000038869 ENSNLEP00000038869 ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038401 ENSNLEP00000038401 ENSNLEP00000037880 ENSNLEP00000037880 ENSNLEP00000037583 ENSNLEP00000037583 PSMB6 PSMB6 ENSNLEP00000029811 ENSNLEP00000029811 PSMF1 PSMF1 RELA RELA PSME2 PSME2 NFATC2 NFATC2 CLEC7A CLEC7A ENSNLEP00000034619 ENSNLEP00000034619 ITPR2 ITPR2 PSMB1 PSMB1 PSMD7 PSMD7 PSME1 PSME1 PSMD14 PSMD14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (939 aa)
ENSNLEP00000031906Uncharacterized protein. (406 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ENSNLEP00000029825Uncharacterized protein. (351 aa)
SYKTyrosine-protein kinase. (532 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD9PDZ domain-containing protein. (222 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (528 aa)
RELBRELB proto-oncogene, NF-kB subunit. (586 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (422 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (529 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
NFKBIANFKB inhibitor alpha. (305 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (272 aa)
NFAT5Nuclear factor of activated T cells 5. (1547 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
KXD1KxDL motif containing 1. (195 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (219 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
MALT1MALT1 paracaspase. (824 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
UBE2MUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (86 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
IKBKGNEMO domain-containing protein. (173 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
PSMA7Proteasome subunit alpha type. (265 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (509 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
PSMA1Proteasome subunit alpha type. (268 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
ENSNLEP00000049245AAA domain-containing protein. (394 aa)
ENSNLEP00000049227Uncharacterized protein. (122 aa)
SRCTyrosine-protein kinase. (537 aa)
ENSNLEP00000048393VWFA domain-containing protein. (326 aa)
LOC100606243UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (188 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (397 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSNLEP00000046239Prot_ATP_ID_OB domain-containing protein. (183 aa)
NFATC3Nuclear factor of activated T cells 3. (1045 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
PSME4Proteasome activator subunit 4. (1821 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
ENSNLEP00000026115AAA domain-containing protein. (339 aa)
PPP3R1Uncharacterized protein. (189 aa)
CCDC71LUncharacterized protein. (293 aa)
LOC100591996Proteasome endopeptidase complex. (164 aa)
PPP3CBSerine/threonine-protein phosphatase. (408 aa)
ENSNLEP00000027432TNF receptor-associated factor. (488 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (488 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMA6Proteasome subunit alpha type. (206 aa)
PSMA4Proteasome subunit alpha type. (241 aa)
ENSNLEP00000029611Proteasome subunit beta. (202 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
ENSNLEP00000042742Proteasome subunit alpha type. (233 aa)
WDR92WD repeat domain 92. (357 aa)
ENSNLEP00000042252Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
ENSNLEP00000042204UBIQUITIN_CONJUGAT_2 domain-containing protein. (131 aa)
ENSNLEP00000041707UBIQUITIN_CONJUGAT_2 domain-containing protein. (77 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
ENSNLEP00000041226ATPase_AAA_core domain-containing protein. (461 aa)
PSMB5Proteasome subunit beta. (263 aa)
BCL10CARD domain-containing protein. (319 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
ENSNLEP00000040208AAA domain-containing protein. (406 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2755 aa)
NFATC1Nuclear factor of activated T cells 1. (968 aa)
PSME3Proteasome activator subunit 3. (239 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
ENSNLEP00000039192Uncharacterized protein. (179 aa)
ENSNLEP00000039157CSN8_PSD8_EIF3K domain-containing protein. (225 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038401ANK_REP_REGION domain-containing protein. (141 aa)
ENSNLEP00000037880Uncharacterized protein. (341 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
PSMB6Proteasome subunit beta. (244 aa)
ENSNLEP00000029811Uncharacterized protein; Belongs to the SKP1 family. (146 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
PSME2Proteasome activator subunit 2. (256 aa)
NFATC2Nuclear factor of activated T cells 2. (905 aa)
CLEC7AC-type lectin domain containing 7A. (247 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSME1Proteasome activator subunit 1. (250 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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