STRINGSTRING
HNRNPH1 HNRNPH1 ENSNLEP00000046563 ENSNLEP00000046563 ENSNLEP00000047217 ENSNLEP00000047217 SRC SRC PTPN11 PTPN11 G1QHL5_NOMLE G1QHL5_NOMLE FGF22 FGF22 FGF16 FGF16 POLR2E POLR2E NCBP2 NCBP2 HNRNPM HNRNPM MAPK3 MAPK3 MKNK2 MKNK2 GTF2F2 GTF2F2 BRAF BRAF POLR2C POLR2C FGF23 FGF23 FGF6 FGF6 ESRP1 ESRP1 FRS3 FRS3 ESRP2 ESRP2 KRAS KRAS GAB1 GAB1 FNDC3B FNDC3B PIK3CA PIK3CA FGF7 FGF7 PLCG1 PLCG1 CBL CBL HRAS HRAS FGF5 FGF5 POLR2L POLR2L POLR2B POLR2B POLR2A POLR2A FGF1 FGF1 FGF3 FGF3 SHC1 SHC1 POLR2I POLR2I PPP2CB PPP2CB G1RR33_NOMLE G1RR33_NOMLE FGF9 FGF9 FGF8 FGF8 GTF2F1 GTF2F1 SOS1 SOS1 FGFR2 FGFR2 HNRNPA1 HNRNPA1 G1SA94_NOMLE G1SA94_NOMLE ERAS ERAS RPS27A-2 RPS27A-2 HNRNPF HNRNPF ENSNLEP00000024736 ENSNLEP00000024736 POLR2D POLR2D PTBP3 PTBP3 FGF20 FGF20 ENSNLEP00000026771 ENSNLEP00000026771 MAPK1 MAPK1 ENSNLEP00000027584 ENSNLEP00000027584 SPRY2 SPRY2 ENSNLEP00000028437 ENSNLEP00000028437 TIAL1 TIAL1 FGF10 FGF10 POLR2H POLR2H PTBP1 PTBP1 ENSNLEP00000030043 ENSNLEP00000030043 MKNK1 MKNK1 PIK3R1 PIK3R1 NCBP1 NCBP1 POLR2G POLR2G PTBP2 PTBP2 ENSNLEP00000034619 ENSNLEP00000034619 LOC100605369 LOC100605369 ENSNLEP00000036514 ENSNLEP00000036514 FRS2 FRS2 PPP2R1A PPP2R1A LOC100580510 LOC100580510 POLR2F POLR2F RBFOX2 RBFOX2 FGF2 FGF2 ENSNLEP00000037204 ENSNLEP00000037204 ENSNLEP00000037583 ENSNLEP00000037583 CSDE1 CSDE1 ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038869 ENSNLEP00000038869 FNDC3A FNDC3A ENSNLEP00000039234 ENSNLEP00000039234 ENSNLEP00000039370 ENSNLEP00000039370 POLR2K POLR2K FGF17 FGF17 NRAS NRAS GRB2 GRB2 PPP2CA PPP2CA LOC101177069 LOC101177069 ENSNLEP00000043688 ENSNLEP00000043688 RPS27A RPS27A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HNRNPH1Uncharacterized protein. (472 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
ENSNLEP00000047217Uncharacterized protein. (67 aa)
SRCTyrosine-protein kinase. (537 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
G1QHL5_NOMLEUncharacterized protein; Belongs to the heparin-binding growth factors family. (182 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
POLR2ERNA polymerase II subunit E. (211 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (166 aa)
HNRNPMHnRNP_M domain-containing protein. (100 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
MKNK2Uncharacterized protein. (272 aa)
GTF2F2General transcription factor IIF subunit 2. (239 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
POLR2CRNA polymerase II subunit C. (248 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ESRP1Epithelial splicing regulatory protein 1. (684 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
ESRP2Epithelial splicing regulatory protein 2. (717 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
CBLCbl proto-oncogene. (905 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (267 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1164 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
SHC1SHC adaptor protein 1. (542 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
G1RR33_NOMLERRM domain-containing protein. (290 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (511 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
HNRNPA1Uncharacterized protein. (372 aa)
G1SA94_NOMLEUncharacterized protein. (55 aa)
ERASES cell expressed Ras. (233 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
HNRNPFHeterogeneous nuclear ribonucleoprotein F. (415 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
POLR2DRNA polymerase II subunit D. (154 aa)
PTBP3Polypyrimidine tract binding protein 3. (554 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
ENSNLEP00000026771Uncharacterized protein. (348 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
ENSNLEP00000028437RRM domain-containing protein. (317 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (337 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
POLR2HRNA polymerase II subunit H. (174 aa)
PTBP1Polypyrimidine tract binding protein 1. (584 aa)
ENSNLEP00000030043RRM domain-containing protein. (273 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (463 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
POLR2GS1 domain-containing protein. (189 aa)
PTBP2Polypyrimidine tract binding protein 2. (537 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
LOC100605369Uncharacterized protein. (571 aa)
ENSNLEP00000036514Uncharacterized protein. (353 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (588 aa)
LOC100580510zf-RNPHF domain-containing protein. (350 aa)
POLR2FUncharacterized protein. (177 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (407 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (287 aa)
ENSNLEP00000037204Uncharacterized protein. (303 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSNLEP00000039234Uncharacterized protein. (193 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
POLR2KUncharacterized protein. (77 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LOC101177069Uncharacterized protein. (304 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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