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| | TAF4 | TATA-box binding protein associated factor 4. (905 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1215 aa) |
| | RPS27A-2 | Ubiquitin-like domain-containing protein. (156 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (583 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1199 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (321 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (350 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2620 aa) |
| | LOC100587940 | Uncharacterized protein. (704 aa) |
| | ENSNLEP00000026316 | Uncharacterized protein. (233 aa) |
| | ENSNLEP00000028102 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (638 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (333 aa) |
| | AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1142 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (311 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | TAF12 | TFIID_20kDa domain-containing protein. (213 aa) |
| | ENSNLEP00000034619 | Ubiquitin-like domain-containing protein. (77 aa) |
| | ENSNLEP00000035465 | Uncharacterized protein. (86 aa) |
| | ENSNLEP00000035860 | TAFII28 domain-containing protein. (179 aa) |
| | ENSNLEP00000036861 | Uncharacterized protein. (119 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (535 aa) |
| | ENSNLEP00000037583 | Ubiquitin-like domain-containing protein. (79 aa) |
| | MDM2 | MDM2 proto-oncogene. (501 aa) |
| | AURKB | Uncharacterized protein. (123 aa) |
| | ENSNLEP00000038579 | Ubiquitin-like domain-containing protein. (104 aa) |
| | ENSNLEP00000038869 | Ubiquitin-like domain-containing protein. (156 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (423 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (250 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | TAF1 | TATA-box binding protein associated factor 1. (1767 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1229 aa) |
| | RFC5 | Replication factor C subunit 5. (354 aa) |
| | TBP | TATA-box binding protein. (328 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (276 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (471 aa) |
| | NOC2L | Uncharacterized protein. (707 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | CHEK1 | Checkpoint kinase 1. (492 aa) |
| | ENSNLEP00000041823 | TAFII28 domain-containing protein. (197 aa) |
| | LOC100595123 | Uncharacterized protein. (262 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (783 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1884 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | LOC100580418 | Uncharacterized protein. (112 aa) |
| | RFC2 | Replication factor C subunit 2. (322 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1059 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (161 aa) |
| | WRN | WRN RecQ like helicase. (1433 aa) |
| | ENSNLEP00000046515 | Uncharacterized protein. (117 aa) |
| | TP53RK | TP53 regulating kinase. (253 aa) |
| | TAF15 | TATA-box binding protein associated factor 15. (601 aa) |
| | ENSNLEP00000048301 | Peptidyl-prolyl cis-trans isomerase. (144 aa) |
| | DNA2 | Uncharacterized protein. (97 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (604 aa) |
| | ENSNLEP00000039422 | Ubiquitin-like domain-containing protein. (136 aa) |
| | NUAK1 | NUAK family kinase 1. (667 aa) |
| | PLK5 | Polo like kinase 5. (324 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (270 aa) |
| | TAF13 | TATA-box binding protein associated factor 13. (124 aa) |
| | CHEK2 | Checkpoint kinase 2. (487 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (240 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (429 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (520 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (320 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) |
| | RMI1 | RecQ mediated genome instability 1. (625 aa) |
| | EXO1 | Exonuclease 1. (840 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (666 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (289 aa) |
| | TAF1L | TATA-box binding protein associated factor 1 like. (1779 aa) |
| | KXD1 | KxDL motif containing 1. (195 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (227 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa) |
| | ATRIP | ATR interacting protein. (791 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (867 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | RBBP8 | Uncharacterized protein. (896 aa) |
| | ANKRD12 | Ankyrin repeat domain 12. (2002 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (403 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (777 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3055 aa) |
| | TAF7L | TAFII55_N domain-containing protein. (424 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (211 aa) |
| | MEIOB | Meiosis specific with OB-fold. (471 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (431 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (361 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) |
| | RMI2 | RecQ mediated genome instability 2. (147 aa) |
| | RECQL4 | RecQ like helicase 4. (1137 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (649 aa) |
| | G1RMB2_NOMLE | Dna2 domain-containing protein. (678 aa) |
| | TAF3 | PHD-type domain-containing protein. (768 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | BLM | BLM RecQ like helicase. (1399 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1313 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (564 aa) |
| | PLK3 | Polo like kinase 3. (641 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (283 aa) |
| | NUAK2 | NUAK family kinase 2. (672 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (800 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
