STRINGSTRING
HCLS1 HCLS1 GOLGB1 GOLGB1 KDELR1 KDELR1 ARL5C ARL5C CD55 CD55 TMED2 TMED2 COG2 COG2 PRR15L PRR15L COPZ2 COPZ2 COG3 COG3 SPAG5 SPAG5 YKT6 YKT6 GOSR1 GOSR1 DYNC1LI2 DYNC1LI2 DYNC1LI1 DYNC1LI1 COPB2 COPB2 NSF NSF ANKDD1B ANKDD1B G1R0B6_NOMLE G1R0B6_NOMLE GORASP1 GORASP1 SMIM7 SMIM7 RAB1B RAB1B COPE COPE LOC105738356 LOC105738356 CAPZB CAPZB TUBA8 TUBA8 USO1 USO1 COG5 COG5 TUBB6 TUBB6 LOC100592418 LOC100592418 LOC100600563 LOC100600563 TUBA4A TUBA4A TUBB1 TUBB1 RAB1A RAB1A TUBA3E TUBA3E LOC100585215 LOC100585215 GOLGA6B GOLGA6B ARL5A ARL5A TUBB2B TUBB2B TUBAL3 TUBAL3 CAPZA2 CAPZA2 DCTN6 DCTN6 DCTN5 DCTN5 COG7 COG7 ANK3 ANK3 ANK1 ANK1 FAM193B FAM193B TSGA13 TSGA13 TUBE1 TUBE1 ACTR10 ACTR10 SPTA1 SPTA1 INS-IGF2 INS-IGF2 SPTBN4 SPTBN4 ARF1 ARF1 SPTB SPTB COPG1 COPG1 GBF1 GBF1 ACTR1A ACTR1A LOC100594805 LOC100594805 KDELR2 KDELR2 DYNC1H1 DYNC1H1 DYNC1I1 DYNC1I1 LOC100581245 LOC100581245 COG4 COG4 ANK2 ANK2 FKBP15 FKBP15 COPB1 COPB1 TUBA1C TUBA1C LOC100585634 LOC100585634 CCDC70 CCDC70 CAPZA3 CAPZA3 DYNLL1 DYNLL1 TMED3 TMED3 CD59 CD59 LOC100587604 LOC100587604 COPA COPA DYNC1I2 DYNC1I2 ENSNLEP00000024815 ENSNLEP00000024815 ARL11 ARL11 ENSNLEP00000026172 ENSNLEP00000026172 TUBB8 TUBB8 ARFGAP3 ARFGAP3 BET1L BET1L TUBB2A TUBB2A ARF3 ARF3 FOLR1 FOLR1 COG1 COG1 LOC100604350 LOC100604350 ENSNLEP00000032432 ENSNLEP00000032432 NAPB NAPB ARCN1 ARCN1 NAPG NAPG GOSR2 GOSR2 NAPA NAPA SPTBN5 SPTBN5 ENSNLEP00000034538 ENSNLEP00000034538 ARFGAP1 ARFGAP1 DCTN3 DCTN3 CAPZA1 CAPZA1 COPZ1 COPZ1 ENSNLEP00000035433 ENSNLEP00000035433 TMED10 TMED10 ENSNLEP00000035532 ENSNLEP00000035532 ENSNLEP00000035761 ENSNLEP00000035761 ENSNLEP00000035887 ENSNLEP00000035887 ENSNLEP00000036252 ENSNLEP00000036252 TUBB4B TUBB4B LOC100587264 LOC100587264 COPG2 COPG2 ENSNLEP00000037698 ENSNLEP00000037698 ENSNLEP00000038580 ENSNLEP00000038580 GOLGA2 GOLGA2 SPTBN1 SPTBN1 ENSNLEP00000039759 ENSNLEP00000039759 ENSNLEP00000039881 ENSNLEP00000039881 SPTBN2 SPTBN2 ARF4 ARF4 ARL5B ARL5B LOC100592597 LOC100592597 ARL14 ARL14 SPTAN1 SPTAN1 TMED7 TMED7 LOC100580376 LOC100580376 STX5 STX5 ENSNLEP00000042480 ENSNLEP00000042480 ENSNLEP00000043363 ENSNLEP00000043363 ENSNLEP00000043511 ENSNLEP00000043511 TUBA4B TUBA4B ARFGAP2 ARFGAP2 TUBB4A TUBB4A COG6 COG6 TMEM115 TMEM115 ENSNLEP00000046761 ENSNLEP00000046761 LOC100594254 LOC100594254 DYNLL2 DYNLL2 ENSNLEP00000047427 ENSNLEP00000047427 BET1 BET1 DCTN1 DCTN1 TMED4 TMED4 ENSNLEP00000048831 ENSNLEP00000048831 KDELR3 KDELR3 TMED9 TMED9 DCTN4 DCTN4 DCTN2 DCTN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCLS1Hematopoietic cell-specific Lyn substrate 1. (476 aa)
GOLGB1Golgin B1. (3269 aa)
KDELR1ER lumen protein-retaining receptor. (95 aa)
ARL5CADP ribosylation factor like GTPase 5C; Belongs to the small GTPase superfamily. Arf family. (163 aa)
CD55Uncharacterized protein. (550 aa)
TMED2Transmembrane p24 trafficking protein 2. (199 aa)
COG2Component of oligomeric golgi complex 2. (679 aa)
PRR15LProline rich 15 like. (103 aa)
COPZ2Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (157 aa)
COG3Component of oligomeric golgi complex 3. (828 aa)
SPAG5Sperm associated antigen 5. (1200 aa)
YKT6YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (198 aa)
GOSR1Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (248 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (457 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
COPB2Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (900 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (748 aa)
ANKDD1BAnkyrin repeat and death domain containing 1B. (528 aa)
G1R0B6_NOMLEConserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family. (511 aa)
GORASP1Golgi reassembly stacking protein 1. (440 aa)
SMIM7Small integral membrane protein 7. (102 aa)
RAB1BRAB1B, member RAS oncogene family. (201 aa)
COPECoatomer protein complex subunit epsilon. (345 aa)
LOC105738356Uncharacterized protein. (196 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (262 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
USO1USO1 vesicle transport factor. (940 aa)
COG5Component of oligomeric golgi complex 5. (830 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (418 aa)
LOC100592418Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (430 aa)
LOC100600563Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
RAB1ARAB1A, member RAS oncogene family. (185 aa)
TUBA3ETubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
LOC100585215Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
GOLGA6BUncharacterized protein. (625 aa)
ARL5AADP ribosylation factor like GTPase 5A; Belongs to the small GTPase superfamily. Arf family. (179 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (232 aa)
DCTN6Dynactin subunit 6. (176 aa)
DCTN5Uncharacterized protein. (152 aa)
COG7Component of oligomeric golgi complex 7. (736 aa)
ANK3Ankyrin 3. (4058 aa)
ANK1Ankyrin 1. (1778 aa)
FAM193BFamily with sequence similarity 193 member B. (752 aa)
TSGA13Testis specific 13. (275 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (475 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (417 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2387 aa)
INS-IGF2INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (203 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2474 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2266 aa)
COPG1Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (872 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
ACTR1AActin related protein 1A. (376 aa)
LOC100594805Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
KDELR2ER lumen protein-retaining receptor. (181 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4646 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
LOC100581245G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the tubulin family. (768 aa)
COG4Component of oligomeric golgi complex 4. (715 aa)
ANK2Ankyrin 2. (3957 aa)
FKBP15Peptidylprolyl isomerase. (1267 aa)
COPB1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (518 aa)
LOC100585634Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (351 aa)
CCDC70Coiled-coil domain containing 70. (233 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
DYNLL1Dynein light chain. (89 aa)
TMED3GOLD domain-containing protein. (251 aa)
CD59UPAR/Ly6 domain-containing protein. (130 aa)
LOC100587604Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
COPACoatomer protein complex subunit alpha. (1070 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
ENSNLEP00000024815Tubulin domain-containing protein. (117 aa)
ARL11ADP ribosylation factor like GTPase 11; Belongs to the small GTPase superfamily. Arf family. (196 aa)
ENSNLEP00000026172Uncharacterized protein. (178 aa)
TUBB8Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (376 aa)
ARFGAP3ADP ribosylation factor GTPase activating protein 3. (516 aa)
BET1LBet1 golgi vesicular membrane trafficking protein like. (111 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ARF3Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
FOLR1Folate receptor alpha. (228 aa)
COG1Component of oligomeric golgi complex 1. (980 aa)
LOC100604350Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
ENSNLEP00000032432Tubulin domain-containing protein. (95 aa)
NAPBNSF attachment protein beta. (280 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (492 aa)
NAPGNSF attachment protein gamma. (312 aa)
GOSR2Uncharacterized protein. (257 aa)
NAPAUncharacterized protein. (72 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3637 aa)
ENSNLEP00000034538Tubulin domain-containing protein; Belongs to the tubulin family. (327 aa)
ARFGAP1ADP ribosylation factor GTPase activating protein 1. (414 aa)
DCTN3Uncharacterized protein. (176 aa)
CAPZA1F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa)
COPZ1Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (192 aa)
ENSNLEP00000035433ANK_REP_REGION domain-containing protein. (517 aa)
TMED10Transmembrane p24 trafficking protein 10. (219 aa)
ENSNLEP00000035532ANK_REP_REGION domain-containing protein. (277 aa)
ENSNLEP00000035761Uncharacterized protein. (122 aa)
ENSNLEP00000035887Uncharacterized protein. (69 aa)
ENSNLEP00000036252Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (428 aa)
LOC100587264Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
COPG2Adaptin_N domain-containing protein. (103 aa)
ENSNLEP00000037698Uncharacterized protein. (134 aa)
ENSNLEP00000038580GOLD domain-containing protein; Belongs to the EMP24/GP25L family. (100 aa)
GOLGA2Golgin A2. (1005 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2289 aa)
ENSNLEP00000039759GOLD domain-containing protein. (183 aa)
ENSNLEP00000039881Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (387 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2353 aa)
ARF4ADP ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
ARL5BADP ribosylation factor like GTPase 5B; Belongs to the small GTPase superfamily. Arf family. (180 aa)
LOC100592597Uncharacterized protein. (642 aa)
ARL14ADP ribosylation factor like GTPase 14; Belongs to the small GTPase superfamily. Arf family. (192 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2410 aa)
TMED7GOLD domain-containing protein. (203 aa)
LOC100580376Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (359 aa)
ENSNLEP00000042480GOLD domain-containing protein. (215 aa)
ENSNLEP00000043363Uncharacterized protein. (174 aa)
ENSNLEP00000043511Uncharacterized protein. (163 aa)
TUBA4BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (237 aa)
ARFGAP2ADP ribosylation factor GTPase activating protein 2. (522 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (372 aa)
COG6Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (657 aa)
TMEM115Transmembrane protein 115. (351 aa)
ENSNLEP00000046761Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (151 aa)
LOC100594254K-box domain-containing protein. (466 aa)
DYNLL2Dynein light chain. (89 aa)
ENSNLEP00000047427Uncharacterized protein; Belongs to the tubulin family. (397 aa)
BET1Bet1 golgi vesicular membrane trafficking protein. (118 aa)
DCTN1CAP-Gly domain-containing protein. (1280 aa)
TMED4GOLD domain-containing protein. (168 aa)
ENSNLEP00000048831F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (255 aa)
KDELR3ER lumen protein-retaining receptor. (186 aa)
TMED9Transmembrane p24 trafficking protein 9. (235 aa)
DCTN4Dynactin subunit 4. (467 aa)
DCTN2Dynactin subunit 2. (377 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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