STRINGSTRING
ENSNLEP00000029811 ENSNLEP00000029811 PSMB7 PSMB7 ENSNLEP00000049245 ENSNLEP00000049245 ENSNLEP00000048393 ENSNLEP00000048393 PSMD13 PSMD13 PSMA5 PSMA5 PSMA6 PSMA6 PSMA4 PSMA4 AKT1 AKT1 ENSNLEP00000029611 ENSNLEP00000029611 PSMD12 PSMD12 ENSNLEP00000027951 ENSNLEP00000027951 LOC100593129 LOC100593129 LOC100591996 LOC100591996 LOC100584595 LOC100584595 ENSNLEP00000026115 ENSNLEP00000026115 PSMA1 PSMA1 CDKN1B CDKN1B AKT3 AKT3 RPS27A-2 RPS27A-2 CDK4 CDK4 PSMD5 PSMD5 PSMC1 PSMC1 PSMD8 PSMD8 LIN52 LIN52 SKP2 SKP2 PSMA7 PSMA7 CCNA1 CCNA1 PSMC3 PSMC3 MAX MAX PSMC4 PSMC4 MNAT1 MNAT1 PSMA3 PSMA3 PSMC6 PSMC6 CKS1B CKS1B LIN37 LIN37 PSMB4 PSMB4 PSMD4 PSMD4 E2F1 E2F1 CCNA2 CCNA2 PSMC2 PSMC2 SKP1 SKP1 CCNE1 CCNE1 KIAA2012 KIAA2012 CABLES1 CABLES1 PSMB9 PSMB9 PSMB8 PSMB8 CDC25A CDC25A KXD1 KXD1 PSMD11 PSMD11 MYC MYC PSMB10 PSMB10 E2F4 E2F4 PSMC5 PSMC5 CUL1 CUL1 CCNE2 CCNE2 RB1 RB1 PSMA2 PSMA2 E2F5 E2F5 FZR1 FZR1 WEE2 WEE2 CDK3 CDK3 PSMD3 PSMD3 PSMD9 PSMD9 RBL2 RBL2 TFDP1 TFDP1 PSMB3 PSMB3 ENSNLEP00000029825 ENSNLEP00000029825 ENSNLEP00000029829 ENSNLEP00000029829 PTK6 PTK6 PSMD10 PSMD10 CCND1 CCND1 ENSNLEP00000031906 ENSNLEP00000031906 ENSNLEP00000032143 ENSNLEP00000032143 PSMD14 PSMD14 PSME1 PSME1 ENSNLEP00000033138 ENSNLEP00000033138 CDK2 CDK2 PSMD7 PSMD7 PSMB1 PSMB1 ENSNLEP00000033819 ENSNLEP00000033819 ENSNLEP00000034619 ENSNLEP00000034619 CDC25B CDC25B ENSNLEP00000035546 ENSNLEP00000035546 LIN9 LIN9 PSME2 PSME2 PSMF1 PSMF1 PSMB6 PSMB6 ENSNLEP00000037083 ENSNLEP00000037083 ENSNLEP00000037583 ENSNLEP00000037583 ENSNLEP00000037880 ENSNLEP00000037880 ENSNLEP00000038401 ENSNLEP00000038401 ENSNLEP00000038579 ENSNLEP00000038579 CDK7 CDK7 CKS2 CKS2 ENSNLEP00000038869 ENSNLEP00000038869 ENSNLEP00000039157 ENSNLEP00000039157 ENSNLEP00000039192 ENSNLEP00000039192 ENSNLEP00000039422 ENSNLEP00000039422 PSME3 PSME3 ENSNLEP00000040208 ENSNLEP00000040208 PSMB5 PSMB5 ENSNLEP00000041226 ENSNLEP00000041226 PSMD1 PSMD1 AKT2 AKT2 ENSNLEP00000042252 ENSNLEP00000042252 CCNH CCNH ENSNLEP00000042742 ENSNLEP00000042742 LIN54 LIN54 PSMD2 PSMD2 PSMB2 PSMB2 RPS27A RPS27A WEE1 WEE1 PSMD6 PSMD6 ENSNLEP00000046239 ENSNLEP00000046239 ENSNLEP00000046336 ENSNLEP00000046336
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSNLEP00000029811Uncharacterized protein; Belongs to the SKP1 family. (146 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSNLEP00000049245AAA domain-containing protein. (394 aa)
ENSNLEP00000048393VWFA domain-containing protein. (326 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (397 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMA6Proteasome subunit alpha type. (206 aa)
PSMA4Proteasome subunit alpha type. (241 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
ENSNLEP00000029611Proteasome subunit beta. (202 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (488 aa)
ENSNLEP00000027951CAF1C_H4-bd domain-containing protein. (97 aa)
LOC100593129Rhodanese domain-containing protein. (501 aa)
LOC100591996Proteasome endopeptidase complex. (164 aa)
LOC100584595WD_REPEATS_REGION domain-containing protein. (408 aa)
ENSNLEP00000026115AAA domain-containing protein. (339 aa)
PSMA1Proteasome subunit alpha type. (268 aa)
CDKN1BUncharacterized protein. (204 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (509 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
LIN52Lin-52 DREAM MuvB core complex component. (116 aa)
SKP2S-phase kinase associated protein 2. (425 aa)
PSMA7Proteasome subunit alpha type. (265 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
MAXMYC associated factor X. (160 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
LIN37Lin-37 DREAM MuvB core complex component. (246 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
E2F1E2F transcription factor 1. (391 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (431 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (402 aa)
KIAA2012KIAA2012. (1116 aa)
CABLES1Cyclin N-terminal domain-containing protein. (368 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (276 aa)
CDC25ACell division cycle 25A. (524 aa)
KXD1KxDL motif containing 1. (195 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
PSMB10Proteasome subunit beta. (272 aa)
E2F4E2F transcription factor 4. (397 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
RB1RB transcriptional corepressor 1. (919 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
E2F5E2F transcription factor 5. (346 aa)
FZR1Fizzy and cell division cycle 20 related 1. (556 aa)
WEE2Wee1-like protein kinase. (552 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (270 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (528 aa)
PSMD9PDZ domain-containing protein. (222 aa)
RBL2RB transcriptional corepressor like 2. (1138 aa)
TFDP1Transcription factor. (395 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSNLEP00000029825Uncharacterized protein. (351 aa)
ENSNLEP00000029829Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (66 aa)
PTK6Tyrosine-protein kinase. (451 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ENSNLEP00000031906Uncharacterized protein. (406 aa)
ENSNLEP00000032143Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (108 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
PSME1Proteasome activator subunit 1. (250 aa)
ENSNLEP00000033138Protein kinase domain-containing protein. (310 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (311 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMB1Proteasome subunit beta. (241 aa)
ENSNLEP00000033819Uncharacterized protein. (375 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
CDC25BRhodanese domain-containing protein. (485 aa)
ENSNLEP00000035546Uncharacterized protein. (50 aa)
LIN9Lin-9 DREAM MuvB core complex component. (615 aa)
PSME2Proteasome activator subunit 2. (256 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB6Proteasome subunit beta. (244 aa)
ENSNLEP00000037083WD_REPEATS_REGION domain-containing protein. (413 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
ENSNLEP00000037880Uncharacterized protein. (341 aa)
ENSNLEP00000038401ANK_REP_REGION domain-containing protein. (141 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (341 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
ENSNLEP00000039157CSN8_PSD8_EIF3K domain-containing protein. (225 aa)
ENSNLEP00000039192Uncharacterized protein. (179 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
PSME3Proteasome activator subunit 3. (239 aa)
ENSNLEP00000040208AAA domain-containing protein. (406 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSNLEP00000041226ATPase_AAA_core domain-containing protein. (461 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
ENSNLEP00000042252Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
ENSNLEP00000042742Proteasome subunit alpha type. (233 aa)
LIN54Lin-54 DREAM MuvB core complex component. (749 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB2Proteasome subunit beta. (201 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
WEE1Wee1-like protein kinase. (645 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSNLEP00000046239Prot_ATP_ID_OB domain-containing protein. (183 aa)
ENSNLEP00000046336Transcription factor. (371 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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