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HSD17B3 HSD17B3 HACD4 HACD4 SLC27A3 SLC27A3 ACSL3 ACSL3 TECRL TECRL SCD5 SCD5 ACSBG1 ACSBG1 HSD17B8 HSD17B8 PPT2 PPT2 SLC27A2 SLC27A2 MORC2 MORC2 MORC1 MORC1 ACACA ACACA LOC100596750 LOC100596750 ELOVL2 ELOVL2 ARMC7 ARMC7 HSD17B12 HSD17B12 ENSNLEP00000034323 ENSNLEP00000034323 ENSNLEP00000034358 ENSNLEP00000034358 HACD2 HACD2 ACSL6 ACSL6 ELOVL7 ELOVL7 HACD1 HACD1 OLAH OLAH CBR4 CBR4 TECR TECR SLC25A1 SLC25A1 HSDL1 HSDL1 ELOVL5 ELOVL5 ACSL1 ACSL1 ACLY ACLY PPT1 PPT1 ELOVL4 ELOVL4 HACD3 HACD3 MORC4 MORC4 FASN FASN ACSL4 ACSL4 SCD SCD ELOVL3 ELOVL3 G1S0L2_NOMLE G1S0L2_NOMLE ACSL5 ACSL5 ACSBG2 ACSBG2 ELOVL6 ELOVL6 HTD2 HTD2 ELOVL1 ELOVL1 MORC3 MORC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HSD17B3Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa)
SLC27A3AMP-binding domain-containing protein. (656 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
TECRLTrans-2,3-enoyl-CoA reductase like. (363 aa)
SCD5FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (257 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (665 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (261 aa)
PPT2Palmitoyl-protein thioesterase 2. (308 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
MORC2MORC family CW-type zinc finger 2. (1032 aa)
MORC1MORC family CW-type zinc finger 1. (984 aa)
ACACAAcetyl-CoA carboxylase alpha. (2338 aa)
LOC100596750Carrier domain-containing protein. (2303 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (295 aa)
ARMC7Armadillo repeat containing 7. (198 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa)
ENSNLEP00000034323S5A_REDUCTASE domain-containing protein. (264 aa)
ENSNLEP00000034358Uncharacterized protein. (268 aa)
HACD2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (231 aa)
ACSL6AMP-binding domain-containing protein. (700 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa)
OLAHOleoyl-ACP hydrolase. (318 aa)
CBR4Carbonyl reductase 4. (237 aa)
TECRS5A_REDUCTASE domain-containing protein. (319 aa)
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (259 aa)
HSDL1Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
ELOVL5Elongation of very long chain fatty acids protein. (326 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1103 aa)
PPT1Palmitoyl-protein thioesterase 1. (326 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (404 aa)
MORC4MORC family CW-type zinc finger 4. (826 aa)
FASNCarrier domain-containing protein. (2417 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (356 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
G1S0L2_NOMLEUncharacterized protein. (532 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (739 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (616 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (164 aa)
ELOVL1Elongation of very long chain fatty acids protein. (286 aa)
MORC3MORC family CW-type zinc finger 3. (915 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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