STRINGSTRING
ITGA2B ITGA2B SYK SYK CRK CRK RAPGEFL1 RAPGEFL1 VWF VWF RAP1A RAP1A FNDC3B FNDC3B RAPGEF4 RAPGEF4 FGB FGB FGA FGA THPO THPO CASS4 CASS4 FN1 FN1 LRRC15 LRRC15 COL1A1 COL1A1 LOC100592336 LOC100592336 RASGRP1 RASGRP1 SHC1 SHC1 TLN2 TLN2 MPL MPL F2 F2 CSK CSK EFS EFS COL1A2 COL1A2 SOS1 SOS1 RAPGEF5 RAPGEF5 APBB1IP APBB1IP GP1BA GP1BA RAPGEF3 RAPGEF3 ADRA2C ADRA2C LOC100588496 LOC100588496 GP1BB GP1BB AKT1 AKT1 RAP1B RAP1B ITGB3 ITGB3 TLN1 TLN1 PTK2 PTK2 ENSNLEP00000036455 ENSNLEP00000036455 RASGRP2 RASGRP2 ADRA2B ADRA2B FNDC3A FNDC3A ENSNLEP00000039370 ENSNLEP00000039370 NEDD9 NEDD9 LOC100593010 LOC100593010 GRB2 GRB2 FGG FGG BCAR1 BCAR1 MFSD8 MFSD8 RAPH1 RAPH1 ENSNLEP00000046563 ENSNLEP00000046563 ENSNLEP00000048405 ENSNLEP00000048405 SRC SRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1040 aa)
SYKTyrosine-protein kinase. (532 aa)
CRKUncharacterized protein. (252 aa)
RAPGEFL1Ras-GEF domain-containing protein. (374 aa)
VWFVon Willebrand factor. (2790 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (925 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (863 aa)
THPOThrombopoietin. (353 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
FN1Fibronectin 1. (2477 aa)
LRRC15Leucine rich repeat containing 15. (587 aa)
COL1A1Collagen type I alpha 1 chain. (1386 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
RASGRP1RAS guanyl releasing protein 1. (785 aa)
SHC1SHC adaptor protein 1. (542 aa)
TLN2Uncharacterized protein. (2289 aa)
MPLFibronectin type-III domain-containing protein. (544 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (613 aa)
CSKTyrosine-protein kinase. (274 aa)
EFSEmbryonal Fyn-associated substrate. (561 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (667 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (679 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (853 aa)
ADRA2CG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
LOC100588496FERM domain-containing protein. (263 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (206 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
RAP1BRAP1B, member of RAS oncogene family. (165 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
TLN1Talin 1. (2542 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
ENSNLEP00000036455Uncharacterized protein. (127 aa)
RASGRP2RAS guanyl releasing protein 2. (610 aa)
ADRA2BG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (838 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FGGFibrinogen gamma chain. (463 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (827 aa)
MFSD8Major facilitator superfamily domain containing 8. (521 aa)
RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (1266 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
ENSNLEP00000048405Uncharacterized protein. (167 aa)
SRCTyrosine-protein kinase. (537 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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