STRINGSTRING
SRMS SRMS KHDRBS3 KHDRBS3 STAT3 STAT3 LPXN LPXN ELMO2 ELMO2 RASA1 RASA1 GPNMB GPNMB RAC1 RAC1 TGFB1I1 TGFB1I1 EGF EGF EPAS1 EPAS1 CDK4 CDK4 LRRK2 LRRK2 RNF222 RNF222 ERAS ERAS RPS27A-2 RPS27A-2 NR3C1 NR3C1 CDKN1B CDKN1B ELMOD1 ELMOD1 ENSNLEP00000026972 ENSNLEP00000026972 ENSNLEP00000027935 ENSNLEP00000027935 AKT1 AKT1 ARAP1 ARAP1 PTK6 PTK6 CCND1 CCND1 CDK2 CDK2 STAP2 STAP2 DOCK1 DOCK1 CRK CRK PSPC1 PSPC1 ELMOD3 ELMOD3 KHDRBS1 KHDRBS1 ELMO1 ELMO1 ARHGAP35 ARHGAP35 ELMO3 ELMO3 ELMOD2 ELMOD2 KRAS KRAS KXD1 KXD1 RHOA RHOA ERBB4 ERBB4 CBL CBL CCNE1 CCNE1 EREG EREG BTC BTC HRAS HRAS NRG2 NRG2 HBEGF HBEGF ERBB2 ERBB2 HIF1A HIF1A PXN PXN ERBB3 ERBB3 NRG3 NRG3 NRG1 NRG1 RPS27A RPS27A NRG4 NRG4 DOK1 DOK1 ENSNLEP00000042609 ENSNLEP00000042609 PELP1 PELP1 BCAR1 BCAR1 NONO NONO NRAS NRAS ENSNLEP00000039422 ENSNLEP00000039422 ENSNLEP00000038869 ENSNLEP00000038869 KHDRBS2 KHDRBS2 ENSNLEP00000038579 ENSNLEP00000038579 CSDE1 CSDE1 ENSNLEP00000037881 ENSNLEP00000037881 ENSNLEP00000037583 ENSNLEP00000037583 ENSNLEP00000036737 ENSNLEP00000036737 EGFR EGFR SFPQ SFPQ ENSNLEP00000034619 ENSNLEP00000034619
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRMSTyrosine-protein kinase. (486 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (346 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (387 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
GPNMBGlycoprotein nmb. (575 aa)
RAC1Rac family small GTPase 1. (187 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (460 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
RNF222Ring finger protein 222. (220 aa)
ERASES cell expressed Ras. (233 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (778 aa)
CDKN1BUncharacterized protein. (204 aa)
ELMOD1ELMO domain containing 1. (334 aa)
ENSNLEP00000026972RRM domain-containing protein. (153 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1384 aa)
PTK6Tyrosine-protein kinase. (451 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (311 aa)
STAP2SH2 domain-containing protein. (301 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
CRKUncharacterized protein. (252 aa)
PSPC1Paraspeckle component 1. (522 aa)
ELMOD3ELMO domain-containing protein. (391 aa)
KHDRBS1KH domain-containing protein. (390 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
ELMO3Engulfment and cell motility 3. (694 aa)
ELMOD2ELMO domain containing 2. (293 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
KXD1KxDL motif containing 1. (195 aa)
RHOARas homolog family member A. (193 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
CBLCbl proto-oncogene. (905 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (402 aa)
EREGEpiregulin. (169 aa)
BTCBetacellulin. (178 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
NRG2Uncharacterized protein. (597 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ERBB2Receptor protein-tyrosine kinase. (1247 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
PXNUncharacterized protein. (1078 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1343 aa)
NRG3Neuregulin 3. (720 aa)
NRG1Neuregulin 1. (713 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
NRG4Neuregulin 4. (117 aa)
DOK1Docking protein 1. (481 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1186 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (827 aa)
NONONon-POU domain containing octamer binding. (463 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
KHDRBS2Uncharacterized protein. (273 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ENSNLEP00000037881IRS-type PTB domain-containing protein. (227 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
SFPQRRM domain-containing protein. (351 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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