STRINGSTRING
HRAS HRAS LPXN LPXN RHOA RHOA BCAR1 BCAR1 CSDE1 CSDE1 KRAS KRAS ELMOD2 ELMOD2 ELMO3 ELMO3 ARHGAP35 ARHGAP35 PXN PXN ELMO1 ELMO1 ELMOD3 ELMOD3 CRK CRK ENSNLEP00000042609 ENSNLEP00000042609 ENSNLEP00000036737 ENSNLEP00000036737 DOCK1 DOCK1 ELMO2 ELMO2 PTK6 PTK6 ENSNLEP00000027935 ENSNLEP00000027935 ELMOD1 ELMOD1 ERAS ERAS RNF222 RNF222 TGFB1I1 TGFB1I1 NRAS NRAS RAC1 RAC1 RASA1 RASA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HRASHRas proto-oncogene, GTPase. (189 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (387 aa)
RHOARas homolog family member A. (193 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (827 aa)
CSDE1Cold shock domain containing E1. (844 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ELMOD2ELMO domain containing 2. (293 aa)
ELMO3Engulfment and cell motility 3. (694 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
PXNUncharacterized protein. (1078 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ELMOD3ELMO domain-containing protein. (391 aa)
CRKUncharacterized protein. (252 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
PTK6Tyrosine-protein kinase. (451 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
ELMOD1ELMO domain containing 1. (334 aa)
ERASES cell expressed Ras. (233 aa)
RNF222Ring finger protein 222. (220 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (460 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RAC1Rac family small GTPase 1. (187 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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