STRINGSTRING
ENSNLEP00000027740 ENSNLEP00000027740 LOC100600196 LOC100600196 HSP90AB1 HSP90AB1 NRIP1 NRIP1 MAPK1 MAPK1 HIST1H2BO HIST1H2BO ENSNLEP00000026915 ENSNLEP00000026915 ENSNLEP00000026679 ENSNLEP00000026679 GNG4 GNG4 GNG13 GNG13 HIST1H2BK HIST1H2BK RAD21 RAD21 TRPS1 TRPS1 G1QWQ9_NOMLE G1QWQ9_NOMLE CBFB CBFB MOV10 MOV10 SRF SRF STAG1 STAG1 GNG3 GNG3 H2AZ2 H2AZ2 NOS3 NOS3 WDR64 WDR64 ELK1 ELK1 H2BC15 H2BC15 H2BU1 H2BU1 POLR2C POLR2C PRMT8 PRMT8 GNGT2 GNGT2 FKBP4 FKBP4 STRN4 STRN4 GNG8 GNG8 PPP5D1 PPP5D1 PPP5C PPP5C HDAC1 HDAC1 SPHK1 SPHK1 GTF2F2 GTF2F2 FOSB FOSB MAPK3 MAPK3 KPNA2 KPNA2 KANK3 KANK3 AGO2 AGO2 ENSNLEP00000025948 ENSNLEP00000025948 HSP90AA1 HSP90AA1 KAT2B KAT2B POLR2D POLR2D LOC100597637 LOC100597637 CDKN1B CDKN1B AKT3 AKT3 MYB MYB FOXO3 FOXO3 SMC3 SMC3 USF1 USF1 UHMK1 UHMK1 H2BC1 H2BC1 ERAS ERAS G1SA94_NOMLE G1SA94_NOMLE LOC100596300 LOC100596300 H2AC20 H2AC20 CITED1 CITED1 NR5A2 NR5A2 CCNT1 CCNT1 SP1 SP1 ZDHHC21 ZDHHC21 CDK9 CDK9 EGF EGF STRN STRN GTF2F1 GTF2F1 GPAM GPAM GNG11 GNG11 GNGT1 GNGT1 ESR1 ESR1 ZC3H12D ZC3H12D KANK4 KANK4 JUN JUN GNAT3 GNAT3 TBPL1 TBPL1 TFF3 TFF3 CHD1 CHD1 GREB1 GREB1 ESR2 ESR2 LOC100599068 LOC100599068 ENSNLEP00000049320 ENSNLEP00000049320 ENSNLEP00000049149 ENSNLEP00000049149 AXIN1 AXIN1 SRC SRC POLR2F POLR2F STRN3 STRN3 LOC100593825 LOC100593825 PTGES3 PTGES3 EPGN EPGN ENSNLEP00000047693 ENSNLEP00000047693 NCOA1 NCOA1 FOS FOS SMC1A SMC1A ENSNLEP00000047217 ENSNLEP00000047217 ENSNLEP00000047148 ENSNLEP00000047148 ENSNLEP00000046925 ENSNLEP00000046925 ENSNLEP00000046563 ENSNLEP00000046563 POLR2J POLR2J PIK3R3 PIK3R3 POU2F1 POU2F1 H2BC13 H2BC13 ENSNLEP00000045034 ENSNLEP00000045034 ENSNLEP00000044921 ENSNLEP00000044921 ENSNLEP00000044869 ENSNLEP00000044869 ENSNLEP00000044724 ENSNLEP00000044724 ENSNLEP00000044711 ENSNLEP00000044711 IGF1R IGF1R DDX5 DDX5 ENSNLEP00000044037 ENSNLEP00000044037 STAG2 STAG2 ENSNLEP00000043756 ENSNLEP00000043756 ENSNLEP00000043421 ENSNLEP00000043421 KCTD6 KCTD6 H2BC3 H2BC3 H2AC6 H2AC6 ENSNLEP00000043021 ENSNLEP00000043021 ENSNLEP00000043017 ENSNLEP00000043017 H2AZ1 H2AZ1 GTF2A2 GTF2A2 ENSNLEP00000042529 ENSNLEP00000042529 LOC100591180 LOC100591180 AKT2 AKT2 LOC100587665 LOC100587665 GNAI3 GNAI3 ENSNLEP00000041604 ENSNLEP00000041604 RUNX1 RUNX1 H3C13 H3C13 ENSNLEP00000040983 ENSNLEP00000040983 LOC100583243 LOC100583243 FOXA1 FOXA1 LOC100593010 LOC100593010 NRAS NRAS AREG AREG H2BC5 H2BC5 H2BC7 H2BC7 POLR2K POLR2K GNG7 GNG7 GNG12 GNG12 ENSNLEP00000039370 ENSNLEP00000039370 ENSNLEP00000039234 ENSNLEP00000039234 ENSNLEP00000039191 ENSNLEP00000039191 ENSNLEP00000039110 ENSNLEP00000039110 CXCL12 CXCL12 H2AX H2AX ENSNLEP00000038319 ENSNLEP00000038319 CSDE1 CSDE1 CTSD CTSD EBAG9 EBAG9 ENSNLEP00000037453 ENSNLEP00000037453 ENSNLEP00000037385 ENSNLEP00000037385 H2BC11 H2BC11 KAT5 KAT5 ENSNLEP00000037007 ENSNLEP00000037007 BCL2 BCL2 ENSNLEP00000036326 ENSNLEP00000036326 EP300 EP300 ENSNLEP00000035926 ENSNLEP00000035926 ENSNLEP00000035849 ENSNLEP00000035849 EGFR EGFR H2BC14 H2BC14 ENSNLEP00000035379 ENSNLEP00000035379 TNRC6B TNRC6B ENSNLEP00000034625 ENSNLEP00000034625 LOC105740194 LOC105740194 PTK2 PTK2 ENSNLEP00000034374 ENSNLEP00000034374 GREB1L GREB1L LOC100595614 LOC100595614 ENSNLEP00000034023 ENSNLEP00000034023 ZC3H12C ZC3H12C ATF2 ATF2 LOC100593400 LOC100593400 GTF2A1 GTF2A1 ENSNLEP00000033669 ENSNLEP00000033669 POLR2G POLR2G H2BW1 H2BW1 H2AC7 H2AC7 ENSNLEP00000032399 ENSNLEP00000032399 CAV1 CAV1 PIK3R1 PIK3R1 CCND1 CCND1 HIST2H2BE HIST2H2BE KDM1A KDM1A YY1 YY1 TLE3 TLE3 GNB5 GNB5 C11orf88 C11orf88 LOC100583914 LOC100583914 ENSNLEP00000030863 ENSNLEP00000030863 GNG2 GNG2 LOC100592963 LOC100592963 ENSNLEP00000030482 ENSNLEP00000030482 H2BC9 H2BC9 GNB3 GNB3 LOC100593203 LOC100593203 POLR2H POLR2H ENSNLEP00000029165 ENSNLEP00000029165 ENSNLEP00000028868 ENSNLEP00000028868 KDM4B KDM4B KANK2 KANK2 CARM1 CARM1 GATA3 GATA3 GNB2 GNB2 AARSD1 AARSD1 POLR2I POLR2I ZC3H12A ZC3H12A SHC1 SHC1 CAV2 CAV2 NCOA2 NCOA2 ZDHHC7 ZDHHC7 AGO1 AGO1 AGO3 AGO3 AGO4 AGO4 USF2 USF2 TGFA TGFA GNG5 GNG5 CREBBP CREBBP XPO1 XPO1 GNAI1 GNAI1 POLR2A POLR2A LOC100592336 LOC100592336 HBEGF HBEGF LOC100586578 LOC100586578 CXXC5 CXXC5 POLR2B POLR2B FKBP5 FKBP5 POLR2L POLR2L S1PR3 S1PR3 KANK1 KANK1 HRAS HRAS BTC BTC EREG EREG ERBB4 ERBB4 MMP3 MMP3 MMP7 MMP7 PGR PGR CREB1 CREB1 MMP2 MMP2 POLR2E POLR2E MED1 MED1 ZC3H12B ZC3H12B TBP TBP PRKCZ PRKCZ GNB1 GNB1 ZNF217 ZNF217 GNAI2 GNAI2 NCOA3 NCOA3 MMP9 MMP9 PPID PPID PIK3R2 PIK3R2 GNB4 GNB4 PIK3CA PIK3CA MYC MYC PRMT1 PRMT1 KRAS KRAS ENSNLEP00000028499 ENSNLEP00000028499 ENSNLEP00000028300 ENSNLEP00000028300 ENSNLEP00000028201 ENSNLEP00000028201 AKT1 AKT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ENSNLEP00000027740Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (91 aa)
LOC100600196Histone domain-containing protein; Belongs to the histone H2B family. (125 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (665 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSNLEP00000026915annotation not available (136 aa)
ENSNLEP00000026679annotation not available (136 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (116 aa)
GNG13G protein subunit gamma 13. (67 aa)
HIST1H2BKHistone H2B; Belongs to the histone H2B family. (126 aa)
RAD21RAD21 cohesin complex component. (631 aa)
TRPS1Transcriptional repressor GATA binding 1. (1294 aa)
G1QWQ9_NOMLEHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
CBFBCore-binding factor subunit beta. (182 aa)
MOV10Mov10 RISC complex RNA helicase. (976 aa)
SRFSerum response factor. (508 aa)
STAG1Stromal antigen 1. (1258 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
WDR64WD repeat domain 64. (1052 aa)
ELK1ETS transcription factor ELK1. (390 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR2CRNA polymerase II subunit C. (248 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (366 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
FKBP4Peptidylprolyl isomerase. (424 aa)
STRN4Striatin 4. (713 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PPP5D1PPP5 tetratricopeptide repeat domain containing 1. (171 aa)
PPP5CSerine/threonine-protein phosphatase. (499 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
SPHK1DAGKc domain-containing protein. (398 aa)
GTF2F2General transcription factor IIF subunit 2. (239 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (499 aa)
KANK3KN motif and ankyrin repeat domains 3. (840 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (847 aa)
ENSNLEP00000025948annotation not available (103 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (853 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (799 aa)
POLR2DRNA polymerase II subunit D. (154 aa)
LOC100597637Histone H3; Belongs to the histone H3 family. (136 aa)
CDKN1BUncharacterized protein. (204 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MYBMYB proto-oncogene, transcription factor. (744 aa)
FOXO3Forkhead box O3. (672 aa)
SMC3Structural maintenance of chromosomes protein. (1191 aa)
USF1Upstream transcription factor 1. (310 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
ERASES cell expressed Ras. (233 aa)
G1SA94_NOMLEUncharacterized protein. (55 aa)
LOC100596300Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (540 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (726 aa)
SP1Sp1 transcription factor. (786 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
CDK9Cyclin dependent kinase 9. (372 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
STRNStriatin. (702 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (511 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
ZC3H12DC3H1-type domain-containing protein. (430 aa)
KANK4KN motif and ankyrin repeat domains 4. (995 aa)
JUNBZIP domain-containing protein; Belongs to the bZIP family. (305 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
TFF3Trefoil factor 3. (94 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1709 aa)
GREB1Growth regulating estrogen receptor binding 1. (1911 aa)
ESR2Estrogen receptor 2. (530 aa)
LOC100599068Histone H3; Belongs to the histone H3 family. (136 aa)
ENSNLEP00000049320annotation not available (130 aa)
ENSNLEP00000049149annotation not available (103 aa)
AXIN1Axin 1. (837 aa)
SRCTyrosine-protein kinase. (537 aa)
POLR2FUncharacterized protein. (177 aa)
STRN3Striatin 3. (797 aa)
LOC100593825Histone H3; Belongs to the histone H3 family. (136 aa)
PTGES3Prostaglandin E synthase 3. (164 aa)
EPGNEpithelial mitogen. (154 aa)
ENSNLEP00000047693annotation not available (136 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
SMC1AStructural maintenance of chromosomes protein. (1230 aa)
ENSNLEP00000047217Uncharacterized protein. (67 aa)
ENSNLEP00000047148annotation not available (136 aa)
ENSNLEP00000046925annotation not available (103 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
POLR2JUncharacterized protein. (56 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
POU2F1POU domain protein. (755 aa)
H2BC13Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSNLEP00000045034annotation not available (103 aa)
ENSNLEP00000044921annotation not available (103 aa)
ENSNLEP00000044869Histone H2B; Belongs to the histone H2B family. (132 aa)
ENSNLEP00000044724Histone H2A; Belongs to the histone H2A family. (109 aa)
ENSNLEP00000044711annotation not available (136 aa)
IGF1RTyrosine-protein kinase receptor. (1199 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
ENSNLEP00000044037Histone H2A; Belongs to the histone H2A family. (115 aa)
STAG2Stromal antigen 2. (1268 aa)
ENSNLEP00000043756Importin subunit alpha; Functions in nuclear protein import. (474 aa)
ENSNLEP00000043421Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (393 aa)
KCTD6Potassium channel tetramerization domain containing 6. (237 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSNLEP00000043021annotation not available (136 aa)
ENSNLEP00000043017HATPase_c domain-containing protein. (648 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
ENSNLEP00000042529CARM1 domain-containing protein. (165 aa)
LOC100591180Histone domain-containing protein. (136 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
LOC100587665Histone H2B; Belongs to the histone H2B family. (126 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ENSNLEP00000041604annotation not available (126 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (485 aa)
H3C13Histone H3; Belongs to the histone H3 family. (136 aa)
ENSNLEP00000040983annotation not available (103 aa)
LOC100583243Histone H3; Belongs to the histone H3 family. (136 aa)
FOXA1Uncharacterized protein. (346 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
AREGEGF-like domain-containing protein. (274 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC7H2B clustered histone 7. (126 aa)
POLR2KUncharacterized protein. (77 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
ENSNLEP00000039234Uncharacterized protein. (193 aa)
ENSNLEP00000039191annotation not available (136 aa)
ENSNLEP00000039110annotation not available (103 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (142 aa)
ENSNLEP00000038319annotation not available (126 aa)
CSDE1Cold shock domain containing E1. (844 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (595 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (258 aa)
ENSNLEP00000037453annotation not available (103 aa)
ENSNLEP00000037385Uncharacterized protein. (437 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (535 aa)
ENSNLEP00000037007Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (786 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSNLEP00000036326Uncharacterized protein. (321 aa)
EP300E1A binding protein p300. (2306 aa)
ENSNLEP00000035926Histone H2A; Belongs to the histone H2A family. (118 aa)
ENSNLEP00000035849CS domain-containing protein. (173 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSNLEP00000035379HATPase_c domain-containing protein. (297 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1727 aa)
ENSNLEP00000034625annotation not available (103 aa)
LOC105740194Histone H2B; Belongs to the histone H2B family. (128 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
ENSNLEP00000034374Uncharacterized protein. (160 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1865 aa)
LOC100595614Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSNLEP00000034023Histone H3; Belongs to the histone H3 family. (129 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (884 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
LOC100593400Histone H3; Belongs to the histone H3 family. (136 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
ENSNLEP00000033669annotation not available (103 aa)
POLR2GS1 domain-containing protein. (189 aa)
H2BW1H2B histone family member W, testis specific; Belongs to the histone H2B family. (176 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSNLEP00000032399Uncharacterized protein. (628 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
HIST2H2BEHistone H2B; Belongs to the histone H2B family. (126 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (759 aa)
YY1Uncharacterized protein. (311 aa)
TLE3TLE family member 3, transcriptional corepressor. (782 aa)
GNB5G protein subunit beta 5. (357 aa)
C11orf88Chromosome 11 open reading frame 88. (195 aa)
LOC100583914Uncharacterized protein. (322 aa)
ENSNLEP00000030863CS domain-containing protein. (186 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
LOC100592963annotation not available (136 aa)
ENSNLEP00000030482annotation not available (103 aa)
H2BC9Histone H2B; Belongs to the histone H2B family. (126 aa)
GNB3G protein subunit beta 3. (335 aa)
LOC100593203Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR2HRNA polymerase II subunit H. (174 aa)
ENSNLEP00000029165Histone H2A; Belongs to the histone H2A family. (89 aa)
ENSNLEP00000028868G protein gamma domain-containing protein. (64 aa)
KDM4BLysine demethylase 4B. (1135 aa)
KANK2KN motif and ankyrin repeat domains 2. (788 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (563 aa)
GATA3GATA binding protein 3. (444 aa)
GNB2G protein subunit beta 2. (325 aa)
AARSD1Uncharacterized protein. (560 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (560 aa)
SHC1SHC adaptor protein 1. (542 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (86 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (345 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
AGO3Argonaute RISC catalytic component 3; Belongs to the argonaute family. (845 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (854 aa)
USF2BHLH domain-containing protein. (224 aa)
TGFATransforming growth factor alpha. (166 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CREBBPCREB binding protein. (2442 aa)
XPO1Exportin 1. (1091 aa)
GNAI1G protein subunit alpha i1. (353 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
LOC100586578Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CXXC5CXXC finger protein 5. (287 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1164 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
KANK1KN motif and ankyrin repeat domains 1. (1352 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
BTCBetacellulin. (178 aa)
EREGEpiregulin. (169 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
MMP7Matrix metallopeptidase 7. (267 aa)
PGRUncharacterized protein. (339 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MMP2Matrix metallopeptidase 2. (647 aa)
POLR2ERNA polymerase II subunit E. (211 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1558 aa)
ZC3H12BZinc finger CCCH-type containing 12B. (836 aa)
TBPTATA-box binding protein. (328 aa)
PRKCZProtein kinase C zeta. (507 aa)
GNB1G protein subunit beta 1. (340 aa)
ZNF217Zinc finger protein 217. (1048 aa)
GNAI2G protein subunit alpha i2. (355 aa)
NCOA3Nuclear receptor coactivator. (1419 aa)
MMP9Matrix metallopeptidase 9. (692 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
PIK3R2Uncharacterized protein. (727 aa)
GNB4G protein subunit beta 4. (340 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (323 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSNLEP00000028499annotation not available (136 aa)
ENSNLEP00000028300TFIIA_gamma_N domain-containing protein. (56 aa)
ENSNLEP00000028201annotation not available (136 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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