STRINGSTRING
UCMA UCMA SMAD4 SMAD4 MAF MAF HDAC3 HDAC3 SATB2 SATB2 YES1 YES1 ZNF521 ZNF521 SMAD1 SMAD1 CBFB CBFB RB1 RB1 GLI3 GLI3 WWTR1 WWTR1 MAPK3 MAPK3 ZNF423 ZNF423 GLI2 GLI2 AR AR SMAD6 SMAD6 SRC SRC HEY1 HEY1 ENSNLEP00000032543 ENSNLEP00000032543 YAP1 YAP1 LOC100588616 LOC100588616 BGLAP BGLAP MAPK1 MAPK1 HDAC6 HDAC6 SP7 SP7 SP8 SP8 HEY2 HEY2 HDAC4 HDAC4 ABL1 ABL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UCMAUpper zone of growth plate and cartilage matrix associated. (138 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (401 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
SATB2DNA-binding protein SATB. (733 aa)
YES1Tyrosine-protein kinase. (519 aa)
ZNF521Zinc finger protein 521. (1311 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CBFBCore-binding factor subunit beta. (182 aa)
RB1RB transcriptional corepressor 1. (919 aa)
GLI3GLI family zinc finger 3. (1502 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
ZNF423Zinc finger protein 423. (1284 aa)
GLI2GLI family zinc finger 2. (1589 aa)
ARUncharacterized protein. (392 aa)
SMAD6Mothers against decapentaplegic homolog. (465 aa)
SRCTyrosine-protein kinase. (537 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
ENSNLEP00000032543Uncharacterized protein. (168 aa)
YAP1Uncharacterized protein. (418 aa)
LOC100588616Runt domain-containing protein. (504 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (100 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
HDAC6Uncharacterized protein. (146 aa)
SP7Sp7 transcription factor. (431 aa)
SP8Sp8 transcription factor. (506 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1051 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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